IRIS
PIRAS, Sandra
 Distribuzione geografica
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Continente #
NA - Nord America 2.304
EU - Europa 1.206
AS - Asia 505
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 9
SA - Sud America 5
AF - Africa 2
Totale 4.041
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Nazione #
US - Stati Uniti d'America 2.291
UA - Ucraina 469
CN - Cina 438
IT - Italia 231
DE - Germania 174
SE - Svezia 135
FI - Finlandia 66
GB - Regno Unito 38
BE - Belgio 29
FR - Francia 23
IN - India 17
TR - Turchia 17
IR - Iran 15
CA - Canada 12
IE - Irlanda 10
AU - Australia 9
HK - Hong Kong 8
RU - Federazione Russa 7
EU - Europa 6
BG - Bulgaria 4
RO - Romania 4
A2 - ???statistics.table.value.countryCode.A2??? 3
AR - Argentina 2
BR - Brasile 2
CI - Costa d'Avorio 2
IL - Israele 2
LU - Lussemburgo 2
NL - Olanda 2
PL - Polonia 2
VN - Vietnam 2
AT - Austria 1
BA - Bosnia-Erzegovina 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
ES - Italia 1
HR - Croazia 1
HU - Ungheria 1
IQ - Iraq 1
JM - Giamaica 1
KH - Cambogia 1
MD - Moldavia 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PK - Pakistan 1
PY - Paraguay 1
RS - Serbia 1
SG - Singapore 1
SK - Slovacchia (Repubblica Slovacca) 1
UZ - Uzbekistan 1
Totale 4.041
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Città #
Chandler 642
Jacksonville 285
Princeton 178
New York 137
Nanjing 130
Dearborn 107
Ann Arbor 92
Sassari 78
Wilmington 70
Ashburn 54
Nanchang 54
Boardman 39
Beijing 33
Woodbridge 30
Shenyang 28
Changsha 27
Mountain View 26
Brussels 25
Hebei 25
Jinan 22
Tianjin 20
Jiaxing 19
Andover 15
Izmir 13
Rome 13
Haikou 12
San Francisco 12
Augusta 11
Dublin 10
Mumbai 10
West Jordan 10
Cagliari 9
Norwalk 9
San Mateo 9
Ardabil 8
Monmouth Junction 8
Taizhou 8
Toronto 8
Zhengzhou 8
Auburn Hills 7
Guangzhou 7
Kunming 7
Ningbo 7
Frankfurt am Main 6
Lanzhou 6
Albissola Marina 5
Chicago 5
Hangzhou 5
Leawood 5
Milan 5
Washington 5
Central 4
Falls Church 4
Helsinki 4
Naples 4
Paris 4
Santa Clara 4
Avellino 3
London 3
Montreal 3
Pars 3
Seattle 3
Sofia 3
Sydney 3
Turin 3
Abidjan 2
Bochum 2
Bologna 2
Busto Arsizio 2
Castel Gandolfo 2
Changchun 2
Dallas 2
Filottrano 2
Francavilla Fontana 2
Fuzhou 2
Genova 2
Houston 2
Leuven 2
Los Angeles 2
Louvain 2
Melbourne 2
Pune 2
Quartu Sant'elena 2
Ravenna 2
Salerno 2
Secaucus 2
São Paulo 2
Tappahannock 2
Tel Aviv 2
Treviso 2
Asunción 1
Badia 1
Barcelona 1
Belgrade 1
Berlin 1
Bratislava 1
Brisbane 1
Budapest 1
Buenos Aires 1
Canberra 1
Totale 2.472
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Nome #
[1,2,3]triazolo[4,5-H]chinoloni: una nuova classe di promettenti chemioterapici antitubercolari 92
Synthesis, cytotoxicity and antiviral evaluation of new series of imidazo[4,5-g]quinoline and pyrido[2,3-g]quinoxalinone derivatives 88
Nuovi derivati chinossalinici inibitori della Diidrofolato Reduttasi (DHFR) e della Timidilato Sintetasi (TS) dellaLeishmania major: risultati preliminari 87
2-[N-Alkyl(R-phenyl)-aminomethyl]-3-phenyl-7trifluoromethylquinoxalines as anticancer agents Inhibitors of folate enzymes 81
Synthesis and antiviral activity of new phenylimidazopyridines and N-benzylidenequinolinamines derived by molecular simplification of phenylimidazo[4,5-g]quinolines 80
Benzotriazole: an overview on its versatile biological behaviour 73
Enhancement of antimicrobial activity of pump inhibitors associating drugs 69
Design, synthesis and antitubercular activity of 4-alkoxy-triazoloquinolones able to inhibit the M. tuberculosis DNA gyrase 68
E-3-aril-(1H-benzotriazol-1-il)acrilonitrili: una nuova classe di inibitori della tubulina ad attività antitumorale 63
Synthesis of 2-(Quinoxalin-2-ylamino-benzotriazolyl) Pentanedioic Derivatives as Potential Anti-Folate Agents 62
Development of oxygen-bridged pyrazole-based structures as cannabinoid receptor 1 ligands 59
1H,6H-triazolo[4,5-e]benzotriazole-3-oxides and 5,5’-(Z)-diazene-1,2-diylbis(2-methyl-2H-1,2,3-benzotriazole) derived from chloronitrobenzotriazoles and hydrazine 59
Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development 58
A combined in silico/in vitro approach unveils common molecular requirements for efficient BVDV RdRp binding of linear aromatic N-polycyclic systems 57
Antiviral activities of 5-chlorobenzotriazole derivatives 56
Benzotriazolilfenilalchilammidi. Una nuova classe di inibitori delle RNA elicasi di virus a singola catena a RNA a genoma positivo e negativo 56
Quinoxaline chemistry.Part 6 Synthesis and evaluation of antiulcer and gastroproctetive activity of 2-[arylmethylmercapto-,arylmethylsulfinyl-,piperazinyl-3-R-substituted]quinoxalines 56
Novel N-aryl nicotinamide derivatives: tacking stock on 3,6-diazabicyclo[3.3.1]heptanes as ligands for neuronal acetylcholine receptors 56
Anti-BVDV Activity Evaluation of Naphthoimidazole Derivatives Compared with Parental Imidazoquinoline Compounds 54
Quinoline tricyclic derivatives. Design, synthesis and preliminary in vitro and in silico antiviral activity against flaviridae family of three new classes of virus encoded RNA- dependent polymerase(RdRp). In: Book of Abstracts 54
Quinoxaline chemistry. Part 15.4-[2-quinoxalylmethylenimino]-benzoylglutamates and benzoates, 4-[2-quinoxalylmethyl-N-methylamino]-benzoylglutamates as analogues of classical antifolate agents. Synthesis, elucidation of structures and in vitro evaluation of antifolate and anticancer activities 53
Analisi Qualitativa Farmaceutica 53
Dichloro-phenyl -benzotriazoles: a new selective class of human respiratory syncytial virus entry inhibitors 53
Quinoxaline chemistry. Part 6- Synthesis and evaluation of antiulcer and gastroprotective activity of 2 –[arylmethylmercapto- arylmethylsulfinyl- piperazinyl- 3- r- substitute] quinoxalines. 52
Benzoyl-piperazinil chinossaline come potenziali antitumorali 50
2(3)-Aryl-thio(oxy)-methylquinoxaline Derivatives: A New Class of P-Glycoprotein-Mediated Drug Efflux Inhibitors 50
Antiviral Activity of Benzotriazole Based Derivatives 50
Quinoxaline derivatives as new inhibitors of coxsackievirus B5 50
Triazolopyridinyl-acrylonitrile derivatives as antimicrotubule agents: synthesis, in vitro and in silico characterization of antiproliferative activity, inhibition of tubulin polymerization and binding thermodynamics 50
Reaction of 5-aminobenzotriazoles with methyl propiolate. Formation of triazolo[4,5-f]quinolines and related compounds. Unusual products in the Michael addition reaction of 2-methyl-2H-5-aminobenzotriazole 49
Preliminary anti-coxsackie activity of novel 1-[4-(5,6-dimethyl(h)1h(2h)-benzotriazol-1(2)-yl)phenyl]-3-alkyl(aryl)ureas 49
[1,2,3]triazolo[4,5-H]chinoloni: una nuova classe di promettenti chemioterapici antitubercolari 49
Inhibition of RNA Helicase of ssRNA+ virus belonging to Flaviviridae, Coronaviridae and Picornaviridae families 49
quinoxaline chemistry.Part 7. 2-[aminobenzoates]-and2-[aminobenzoylglutamate]-quinoxalines as classical antifolate agents. Sinthesis and evaluation of in vitro anticancer, anti- HIV and antifungal activity 48
Synthesis and anti-mycobacterial activities of triazoloquinolones 48
Synthesis and evaluation of gastroprotective and antiulcer activity of some 2- substituted-1H-imidazo[4,5-b] pyridines and -1H-benzimidazoles 48
Novel 3-benzoyl-2-piperazinylquinoxaline derivatives as potential antitumor agents 48
3-Aryl-2-[1H-benzotriazol-1-yl]acrylonitriles: A novel classo f potent tubulin inhibitors 47
Anti-mycobacterial activity of quinolones. Triazoloquinolones a new class of potent anti mycobacterial agents 47
Inhibition of Enterovirus A71 by a Novel 2-Phenyl-Benzimidazole Derivative 47
Quinoxaline chemistry. Part 14. 4-(2-quinoxalylamino)-phenylacetates and 4-(2-quinoxalylamino)-phenylacetyl-L-glutamates as analogues-homologues of classical antifolate agents. Synthesis and evaluation of in vitro anticancer activity 46
Solid Lipid Nanoparticles as Formulative Strategy to Increase Oral Permeation of a Molecule Active in Multidrug-Resistant Tuberculosis Management 46
Triazolochinoloni. Una nuova classe di agenti antitubercolari attivi su ceppi MDR di M. tuberculosis 46
Systhesis and evaluation of gastroprotective activity of omeprazole imidazo(4,5-b) pyridine and quinoxaline 2- substituted derivatives. 45
Development of folates analogs against folate-dependent enzymes 45
Synthesis and in vitro evaluation of the anti-viral activity of N-[4-(1H(2H)-benzotriazol-1(2)-yl)phenyl]alkylcarboxamides 45
Quinoxaline analogues-homologues of methotrexate 44
Chemistry, biological properties and SAR analysis of quinoxalinones 44
Synthesis and biological evaluation of novel indole-derived thioureas 44
Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells 43
Manuale di analisi farmaceutica. Analisi organica qualitativa non strumentale 42
Quinoxaline Chemistry. Part 17. 4[3,6(7) disubstituted-2-quinoxalinyl-oxa]phenylacetate and phenylacetylglutamate analogues of methotrexate: Synthesis and evaluation of in vitro anticancer activity 42
SAR and Anti-Mycobacterial Activity of Quinolones and Triazoloquinolones: An Update 41
Synthesis and evaluation of gastroprotective and antiulcer of some 2-substituted- 1H- imidazo[4,5-b]pyridines and 1H- benzimidazoles. 41
Ligand-based virtual screening and ADME-tox guided approach to identify triazolo-quinoxalines as folate cycle inhibitors 41
4,7-FENANTROLINE: UNA NUOVA CLASSE DI INIBITORI DELLA POLIMERASI DI RNA-VIRUS 40
5,6-Dichloro-2-phenyl-benzotriazoles: New potent inhibitors of orthohantavirus 39
Synthesis, Antitumor and Antiviral In Vitro Activities of New Benzotriazole-Dicarboxamide Derivatives 39
Synthesis and anti-picornaviridae in vitro activity of a new class of helicase inhibitors the N,N'-bis[4-(1H(2H)-benzotriazol-1(2)-yl)fenyl]alkyldicarboxamides 39
Synthesis and evaluation of gastroprotective activity of omeprazole related benzimidazole, imidazo(4,5-b)pyridine and quinoxaline 2-substituted derivatives 38
Chasing the evaders. Design, Synthesis, Activity, and Molecular Modeling of a New Small Molecule with Activity Against Drug-Resistant HIV-1 mutants 36
Activity and molecular modeling of a new small molecule active against NNRTI-resistant HIV-1 mutants 36
Biological Effects on μ-Receptors Affinity and Selectivity of Arylpropenyl Chain Structural Modification on Diazatricyclodecane Derivatives. . 36
Manuale di analisi qualitativa. Con e-book. EDISES 35
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs) 35
Synthesis and in vitro anticancer evaluatio of variously substituted 3- phenoxymethyl quinoxalin-2-ones and quinoxalines in combination with various drugs against kb mdr tumor cells 34
Quinoline tricyclic derivatives. Design, synthesis and evaluation of the antiviral activity of three new classes of RNA-Dependent RNA Polymerase inhibitors 34
Quinoline triciclic derivatives. Design, synthesis and preliminary in vitro and in silico antiviral activity against flaviviridae family of three new classes of viruses-encoded RNA-dependent RNA polymerase (RdRp) inhibitors 33
Synthesis and in vitro evaluation of the antiviral activity of a series of novel N-[4-(1H(2H)-benzotriazol-1(2)-yl)phenyl]alkylcarboxamides 33
Reactions Of Alkylation Of Biologically Interesting Triazolo[4,5-g]Quinolines And Triazolo[4,5-g]Quinoline-1-Oxides With Electrophilic Reagents 33
Spermidine/spermine N1-acetyltranferase modulation by novel folate cycle inhibitors in cisplatin-sensitive and -resistant human ovarian cancer cell lines 32
Novel quinoxaline analogues as inhibitors of folate enzimes 31
nuovi derivari chinossalinici inibitori della diidrofolato reduttasi (DHFR) e della timidilato sintetasi (TS) della leishmania major: risultati preliminari 31
Quinoline tricyclic derivatives. Design, synthesis and preliminary in vitro and in silico antiviral activity against flaviviridae family of three new classes of virus-encoded RNA-dependent RNA polymerase (RdRp) inhibitors 31
Sintesi di una nuova serie di N-[4-(1H(2H)-benzotriazol-1(2)-il)fenil]alchilcarbossiammidi e N,N'-bis[4-(1H(2H)-benzotriazol-1(2)-il)fenil]alchildicarbossiammidi a potenziale attività antivirale 30
Quinoxaline analogues-homologues of classical antifolates 29
Sintesi ed attività antiulcera di 2-arilmetilmercapto-, 2-solfinilarilchinossaline 29
Synthesis of linear azolo and pyrido quinolines from quinoline derivatives 29
Sintesi di nuove 6,7- diamminochinoline quali intermedi per la preparazione di molecole ad attività biologica 29
Phytochemical compositions and biological activities of essential oils from the leaves, rhizomes and whole plant of hornstedtia bella Škorničk 29
Synthesis and evaluation of antiulcer and gastroprotective activity of 2-[arylmethylmercapto-, arylmethylsulfinyl-, piperazinyl-3-r-substituted] quinoxalines 28
Helicase inhibitors as anti-RNA virus agents 27
Synthesis of variously substituted 3- phenoxymethyl quinoxalin-2-ones and quinoxalines capable to potentiate in vitro the antiproliferative activity of anticancer drugs in multi-drug resistant cell lines 26
Sinthesis and evaluation of gastroproctetive activity of omeprazole related benzimidazole,imidazo[4,5-b]pyridine and quinoxaline 2-substituted derivatives 25
E-3-aril-2-(1H-benzotriazol-1-il)acrilonitrili: una nuova classe di inibitori della tubulina ad attività antitumorale 20
Design, synthesis, and biological screening of a series of 4′-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) 18
Inhibition of RNA helicases of ssRNA+virus belonging toFlaviviridae,CoronaviridaeandPicornaviridaefamilies 18
Improving in vivo oral bioavailability of a poorly soluble drug: a case study on polymeric versus lipid nanoparticles 16
Benzimidazole-2-Phenyl-Carboxamides as Dual-Target Inhibitors of BVDV Entry and Replication 14
Human Enterovirus B: Selective Inhibition by Quinoxaline Derivatives and Bioinformatic RNA-Motif Identification as New Targets 13
Design, synthesis, and biological screening of a series of 4 '-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) 13
Design, Synthesis, and Antiviral Activities of New Benzotriazole-Based Derivatives 12
Sintesi di nuove 6,7-diamminochinoline quali intermedi per la preparazione di molecole ad attività biologica 12
Sintesi di una nuova serie di n-[4-(1H(2H)-benzotriazol-1(2)- il)fenil]alchilcarbossiammidi e n,n'-bis[4-(1H(2H)-benzotriazol- 1(2)-il)fenil]alchildicarbossiammidi a potenziale attività antivirale 12
Antibiotics and Carbohydrate-Containing Drugs Targeting Bacterial Cell Envelopes: An Overview 11
Antiviral activity of benzotriazole based derivatives 10
Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development 10
Analisi Farmaceutica Qualitativa 9
anti-BVDV Activity evaluation of Naphthoimidazole derivatives compared with parentalimidazoquinoline compounds 7
Quinoxaline-based efflux pump inhibitors restore drug susceptibility in drug-resistant nontuberculous mycobacteria 3
Totale 4.117
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Categoria #
all - tutte 17.485
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 17.485
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/201969 0 0 0 0 0 0 0 0 0 0 10 59
2019/2020836 189 2 67 4 75 99 208 8 84 22 76 2
2020/2021695 76 2 104 14 84 28 88 18 97 99 69 16
2021/2022505 67 2 5 12 6 11 16 30 53 52 61 190
2022/20231.266 106 103 31 213 100 197 15 162 205 21 70 43
2023/2024393 56 26 19 12 83 132 10 35 1 19 0 0
Totale 4.117