IRIS
PIRAS, Sandra
 Distribuzione geografica
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Continente #
NA - Nord America 2.275
EU - Europa 1.288
AS - Asia 580
Continente sconosciuto - Info sul continente non disponibili 9
OC - Oceania 9
SA - Sud America 5
AF - Africa 2
Totale 4.168
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Nazione #
US - Stati Uniti d'America 2.262
UA - Ucraina 467
CN - Cina 438
IT - Italia 293
DE - Germania 182
SE - Svezia 134
FI - Finlandia 66
SG - Singapore 56
GB - Regno Unito 38
BE - Belgio 29
FR - Francia 23
KR - Corea 20
IN - India 17
TR - Turchia 17
CZ - Repubblica Ceca 15
IR - Iran 15
CA - Canada 12
IE - Irlanda 10
RU - Federazione Russa 9
AU - Australia 8
HK - Hong Kong 7
EU - Europa 6
BG - Bulgaria 4
RO - Romania 4
A2 - ???statistics.table.value.countryCode.A2??? 3
AR - Argentina 2
BR - Brasile 2
CI - Costa d'Avorio 2
IL - Israele 2
LU - Lussemburgo 2
NL - Olanda 2
PL - Polonia 2
VN - Vietnam 2
AT - Austria 1
BA - Bosnia-Erzegovina 1
DK - Danimarca 1
HR - Croazia 1
HU - Ungheria 1
IQ - Iraq 1
JM - Giamaica 1
JP - Giappone 1
KH - Cambogia 1
MD - Moldavia 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PK - Pakistan 1
PY - Paraguay 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
UZ - Uzbekistan 1
Totale 4.168
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Città #
Chandler 631
Jacksonville 285
Princeton 176
Nanjing 130
New York 125
Dearborn 107
Ann Arbor 92
Sassari 83
Wilmington 69
Nanchang 54
Ashburn 53
Boardman 44
Singapore 39
Beijing 33
Woodbridge 30
Shenyang 28
Changsha 27
Brussels 25
Hebei 25
Mountain View 24
Jinan 22
Seoul 20
Tianjin 20
Jiaxing 19
Andover 15
Brno 14
Izmir 13
Rome 13
Haikou 12
San Francisco 12
Augusta 11
Dallas 10
Dublin 10
Mumbai 10
Munich 10
West Jordan 10
Cagliari 9
Norwalk 9
San Mateo 9
Ardabil 8
Monmouth Junction 8
Taizhou 8
Toronto 8
Zhengzhou 8
Auburn Hills 7
Guangzhou 7
Kunming 7
Ningbo 7
Lanzhou 6
Milan 6
Albissola Marina 5
Chicago 5
Hangzhou 5
Leawood 5
Naples 5
Paris 5
Santa Clara 5
Washington 5
Falls Church 4
Helsinki 4
Palermo 4
Avellino 3
Central 3
Frankfurt am Main 3
London 3
Montreal 3
Pars 3
Sofia 3
Sydney 3
Turin 3
Verona 3
Verrua Savoia 3
Abidjan 2
Bochum 2
Bologna 2
Busto Arsizio 2
Castel Gandolfo 2
Changchun 2
Filottrano 2
Francavilla Fontana 2
Fuzhou 2
Genova 2
Houston 2
Leuven 2
Los Angeles 2
Louvain 2
Nuremberg 2
Padova 2
Pune 2
Quartu Sant'elena 2
Ravenna 2
Salerno 2
Seattle 2
Secaucus 2
São Paulo 2
Tappahannock 2
Tel Aviv 2
Treviso 2
Venice 2
Asunción 1
Totale 2.548
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Nome #
Nuovi derivati chinossalinici inibitori della Diidrofolato Reduttasi (DHFR) e della Timidilato Sintetasi (TS) dellaLeishmania major: risultati preliminari 149
[1,2,3]triazolo[4,5-H]chinoloni: una nuova classe di promettenti chemioterapici antitubercolari 96
Synthesis, cytotoxicity and antiviral evaluation of new series of imidazo[4,5-g]quinoline and pyrido[2,3-g]quinoxalinone derivatives 90
2-[N-Alkyl(R-phenyl)-aminomethyl]-3-phenyl-7trifluoromethylquinoxalines as anticancer agents Inhibitors of folate enzymes 83
Synthesis and antiviral activity of new phenylimidazopyridines and N-benzylidenequinolinamines derived by molecular simplification of phenylimidazo[4,5-g]quinolines 80
Benzotriazole: an overview on its versatile biological behaviour 77
Design, synthesis and antitubercular activity of 4-alkoxy-triazoloquinolones able to inhibit the M. tuberculosis DNA gyrase 71
Enhancement of antimicrobial activity of pump inhibitors associating drugs 69
E-3-aril-(1H-benzotriazol-1-il)acrilonitrili: una nuova classe di inibitori della tubulina ad attività antitumorale 63
Synthesis of 2-(Quinoxalin-2-ylamino-benzotriazolyl) Pentanedioic Derivatives as Potential Anti-Folate Agents 63
1H,6H-triazolo[4,5-e]benzotriazole-3-oxides and 5,5’-(Z)-diazene-1,2-diylbis(2-methyl-2H-1,2,3-benzotriazole) derived from chloronitrobenzotriazoles and hydrazine 63
A combined in silico/in vitro approach unveils common molecular requirements for efficient BVDV RdRp binding of linear aromatic N-polycyclic systems 60
Development of oxygen-bridged pyrazole-based structures as cannabinoid receptor 1 ligands 60
Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development 59
Antiviral activities of 5-chlorobenzotriazole derivatives 58
Anti-BVDV Activity Evaluation of Naphthoimidazole Derivatives Compared with Parental Imidazoquinoline Compounds 58
Benzotriazolilfenilalchilammidi. Una nuova classe di inibitori delle RNA elicasi di virus a singola catena a RNA a genoma positivo e negativo 57
Quinoxaline chemistry.Part 6 Synthesis and evaluation of antiulcer and gastroproctetive activity of 2-[arylmethylmercapto-,arylmethylsulfinyl-,piperazinyl-3-R-substituted]quinoxalines 57
Quinoline tricyclic derivatives. Design, synthesis and preliminary in vitro and in silico antiviral activity against flaviridae family of three new classes of virus encoded RNA- dependent polymerase(RdRp). In: Book of Abstracts 57
Novel N-aryl nicotinamide derivatives: tacking stock on 3,6-diazabicyclo[3.3.1]heptanes as ligands for neuronal acetylcholine receptors 56
Analisi Qualitativa Farmaceutica 55
Dichloro-phenyl -benzotriazoles: a new selective class of human respiratory syncytial virus entry inhibitors 54
Quinoxaline chemistry. Part 15.4-[2-quinoxalylmethylenimino]-benzoylglutamates and benzoates, 4-[2-quinoxalylmethyl-N-methylamino]-benzoylglutamates as analogues of classical antifolate agents. Synthesis, elucidation of structures and in vitro evaluation of antifolate and anticancer activities 53
[1,2,3]triazolo[4,5-H]chinoloni: una nuova classe di promettenti chemioterapici antitubercolari 53
Quinoxaline chemistry. Part 6- Synthesis and evaluation of antiulcer and gastroprotective activity of 2 –[arylmethylmercapto- arylmethylsulfinyl- piperazinyl- 3- r- substitute] quinoxalines. 52
Benzoyl-piperazinil chinossaline come potenziali antitumorali 51
2(3)-Aryl-thio(oxy)-methylquinoxaline Derivatives: A New Class of P-Glycoprotein-Mediated Drug Efflux Inhibitors 51
Quinoxaline derivatives as new inhibitors of coxsackievirus B5 51
Anti-mycobacterial activity of quinolones. Triazoloquinolones a new class of potent anti mycobacterial agents 50
Preliminary anti-coxsackie activity of novel 1-[4-(5,6-dimethyl(h)1h(2h)-benzotriazol-1(2)-yl)phenyl]-3-alkyl(aryl)ureas 50
Triazolopyridinyl-acrylonitrile derivatives as antimicrotubule agents: synthesis, in vitro and in silico characterization of antiproliferative activity, inhibition of tubulin polymerization and binding thermodynamics 50
quinoxaline chemistry.Part 7. 2-[aminobenzoates]-and2-[aminobenzoylglutamate]-quinoxalines as classical antifolate agents. Sinthesis and evaluation of in vitro anticancer, anti- HIV and antifungal activity 49
3-Aryl-2-[1H-benzotriazol-1-yl]acrylonitriles: A novel classo f potent tubulin inhibitors 49
Inhibition of Enterovirus A71 by a Novel 2-Phenyl-Benzimidazole Derivative 49
Reaction of 5-aminobenzotriazoles with methyl propiolate. Formation of triazolo[4,5-f]quinolines and related compounds. Unusual products in the Michael addition reaction of 2-methyl-2H-5-aminobenzotriazole 49
Synthesis and anti-mycobacterial activities of triazoloquinolones 49
Inhibition of RNA Helicase of ssRNA+ virus belonging to Flaviviridae, Coronaviridae and Picornaviridae families 49
Solid Lipid Nanoparticles as Formulative Strategy to Increase Oral Permeation of a Molecule Active in Multidrug-Resistant Tuberculosis Management 48
Synthesis and evaluation of gastroprotective and antiulcer activity of some 2- substituted-1H-imidazo[4,5-b] pyridines and -1H-benzimidazoles 48
Novel 3-benzoyl-2-piperazinylquinoxaline derivatives as potential antitumor agents 48
Quinoxaline chemistry. Part 14. 4-(2-quinoxalylamino)-phenylacetates and 4-(2-quinoxalylamino)-phenylacetyl-L-glutamates as analogues-homologues of classical antifolate agents. Synthesis and evaluation of in vitro anticancer activity 47
Development of folates analogs against folate-dependent enzymes 46
Triazolochinoloni. Una nuova classe di agenti antitubercolari attivi su ceppi MDR di M. tuberculosis 46
Systhesis and evaluation of gastroprotective activity of omeprazole imidazo(4,5-b) pyridine and quinoxaline 2- substituted derivatives. 45
Synthesis and biological evaluation of novel indole-derived thioureas 45
Synthesis and in vitro evaluation of the anti-viral activity of N-[4-(1H(2H)-benzotriazol-1(2)-yl)phenyl]alkylcarboxamides 45
Quinoxaline analogues-homologues of methotrexate 44
Chemistry, biological properties and SAR analysis of quinoxalinones 44
Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells 44
Manuale di analisi farmaceutica. Analisi organica qualitativa non strumentale 43
Quinoxaline Chemistry. Part 17. 4[3,6(7) disubstituted-2-quinoxalinyl-oxa]phenylacetate and phenylacetylglutamate analogues of methotrexate: Synthesis and evaluation of in vitro anticancer activity 43
SAR and Anti-Mycobacterial Activity of Quinolones and Triazoloquinolones: An Update 42
5,6-Dichloro-2-phenyl-benzotriazoles: New potent inhibitors of orthohantavirus 42
4,7-FENANTROLINE: UNA NUOVA CLASSE DI INIBITORI DELLA POLIMERASI DI RNA-VIRUS 41
Synthesis, Antitumor and Antiviral In Vitro Activities of New Benzotriazole-Dicarboxamide Derivatives 41
Synthesis and evaluation of gastroprotective and antiulcer of some 2-substituted- 1H- imidazo[4,5-b]pyridines and 1H- benzimidazoles. 41
Ligand-based virtual screening and ADME-tox guided approach to identify triazolo-quinoxalines as folate cycle inhibitors 41
Synthesis and anti-picornaviridae in vitro activity of a new class of helicase inhibitors the N,N'-bis[4-(1H(2H)-benzotriazol-1(2)-yl)fenyl]alkyldicarboxamides 40
Synthesis and evaluation of gastroprotective activity of omeprazole related benzimidazole, imidazo(4,5-b)pyridine and quinoxaline 2-substituted derivatives 40
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs) 39
Biological Effects on μ-Receptors Affinity and Selectivity of Arylpropenyl Chain Structural Modification on Diazatricyclodecane Derivatives. . 39
Chasing the evaders. Design, Synthesis, Activity, and Molecular Modeling of a New Small Molecule with Activity Against Drug-Resistant HIV-1 mutants 37
Manuale di analisi qualitativa. Con e-book. EDISES 36
Activity and molecular modeling of a new small molecule active against NNRTI-resistant HIV-1 mutants 36
Quinoline tricyclic derivatives. Design, synthesis and evaluation of the antiviral activity of three new classes of RNA-Dependent RNA Polymerase inhibitors 36
Synthesis and in vitro anticancer evaluatio of variously substituted 3- phenoxymethyl quinoxalin-2-ones and quinoxalines in combination with various drugs against kb mdr tumor cells 34
Reactions Of Alkylation Of Biologically Interesting Triazolo[4,5-g]Quinolines And Triazolo[4,5-g]Quinoline-1-Oxides With Electrophilic Reagents 34
Quinoline triciclic derivatives. Design, synthesis and preliminary in vitro and in silico antiviral activity against flaviviridae family of three new classes of viruses-encoded RNA-dependent RNA polymerase (RdRp) inhibitors 33
Synthesis and in vitro evaluation of the antiviral activity of a series of novel N-[4-(1H(2H)-benzotriazol-1(2)-yl)phenyl]alkylcarboxamides 33
Novel quinoxaline analogues as inhibitors of folate enzimes 32
nuovi derivari chinossalinici inibitori della diidrofolato reduttasi (DHFR) e della timidilato sintetasi (TS) della leishmania major: risultati preliminari 32
Quinoline tricyclic derivatives. Design, synthesis and preliminary in vitro and in silico antiviral activity against flaviviridae family of three new classes of virus-encoded RNA-dependent RNA polymerase (RdRp) inhibitors 32
Spermidine/spermine N1-acetyltranferase modulation by novel folate cycle inhibitors in cisplatin-sensitive and -resistant human ovarian cancer cell lines 32
Sintesi di una nuova serie di N-[4-(1H(2H)-benzotriazol-1(2)-il)fenil]alchilcarbossiammidi e N,N'-bis[4-(1H(2H)-benzotriazol-1(2)-il)fenil]alchildicarbossiammidi a potenziale attività antivirale 31
Phytochemical compositions and biological activities of essential oils from the leaves, rhizomes and whole plant of hornstedtia bella Škorničk 31
Sintesi ed attività antiulcera di 2-arilmetilmercapto-, 2-solfinilarilchinossaline 30
Synthesis of linear azolo and pyrido quinolines from quinoline derivatives 30
Quinoxaline analogues-homologues of classical antifolates 29
Synthesis and evaluation of antiulcer and gastroprotective activity of 2-[arylmethylmercapto-, arylmethylsulfinyl-, piperazinyl-3-r-substituted] quinoxalines 29
Sintesi di nuove 6,7- diamminochinoline quali intermedi per la preparazione di molecole ad attività biologica 29
Helicase inhibitors as anti-RNA virus agents 29
Synthesis of variously substituted 3- phenoxymethyl quinoxalin-2-ones and quinoxalines capable to potentiate in vitro the antiproliferative activity of anticancer drugs in multi-drug resistant cell lines 28
Sinthesis and evaluation of gastroproctetive activity of omeprazole related benzimidazole,imidazo[4,5-b]pyridine and quinoxaline 2-substituted derivatives 26
E-3-aril-2-(1H-benzotriazol-1-il)acrilonitrili: una nuova classe di inibitori della tubulina ad attività antitumorale 21
Inhibition of RNA helicases of ssRNA+virus belonging toFlaviviridae,CoronaviridaeandPicornaviridaefamilies 19
Improving in vivo oral bioavailability of a poorly soluble drug: a case study on polymeric versus lipid nanoparticles 17
Antibiotics and Carbohydrate-Containing Drugs Targeting Bacterial Cell Envelopes: An Overview 17
Design, Synthesis, and Antiviral Activities of New Benzotriazole-Based Derivatives 17
Design, synthesis, and biological screening of a series of 4′-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) 17
Benzimidazole-2-Phenyl-Carboxamides as Dual-Target Inhibitors of BVDV Entry and Replication 16
Analisi Farmaceutica Qualitativa 15
Antiviral activity of benzotriazole based derivatives 14
Human Enterovirus B: Selective Inhibition by Quinoxaline Derivatives and Bioinformatic RNA-Motif Identification as New Targets 13
Sintesi di nuove 6,7-diamminochinoline quali intermedi per la preparazione di molecole ad attività biologica 13
Sintesi di una nuova serie di n-[4-(1H(2H)-benzotriazol-1(2)- il)fenil]alchilcarbossiammidi e n,n'-bis[4-(1H(2H)-benzotriazol- 1(2)-il)fenil]alchildicarbossiammidi a potenziale attività antivirale 13
Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development 12
Quinoxaline-based efflux pump inhibitors restore drug susceptibility in drug-resistant nontuberculous mycobacteria 4
Totale 4.239
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Categoria #
all - tutte 21.570
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.570
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020647 0 2 67 4 75 99 208 8 84 22 76 2
2020/2021684 76 2 104 14 80 26 87 16 96 98 69 16
2021/2022501 67 2 5 12 6 11 16 30 51 51 61 189
2022/20231.232 105 101 31 206 98 193 14 157 198 20 66 43
2023/2024510 56 24 17 12 76 122 10 30 1 19 59 84
2024/202554 29 25 0 0 0 0 0 0 0 0 0 0
Totale 4.239