IRIS
SECHI, Mario
 Distribuzione geografica
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Continente #
NA - Nord America 2.897
EU - Europa 1.603
AS - Asia 1.086
OC - Oceania 16
SA - Sud America 16
AF - Africa 14
Continente sconosciuto - Info sul continente non disponibili 8
Totale 5.640
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Nazione #
US - Stati Uniti d'America 2.872
UA - Ucraina 633
CN - Cina 564
SG - Singapore 409
DE - Germania 267
IT - Italia 238
SE - Svezia 174
FI - Finlandia 99
GB - Regno Unito 67
CZ - Repubblica Ceca 37
FR - Francia 33
TR - Turchia 24
CA - Canada 23
SA - Arabia Saudita 23
KR - Corea 22
AU - Australia 15
BE - Belgio 15
HK - Hong Kong 12
BR - Brasile 8
EG - Egitto 8
IN - India 7
ES - Italia 6
NL - Olanda 6
EU - Europa 5
IL - Israele 4
VE - Venezuela 4
A2 - ???statistics.table.value.countryCode.A2??? 3
IR - Iran 3
MA - Marocco 3
MD - Moldavia 3
QA - Qatar 3
RO - Romania 3
RU - Federazione Russa 3
AR - Argentina 2
AT - Austria 2
BD - Bangladesh 2
CH - Svizzera 2
EE - Estonia 2
JP - Giappone 2
LT - Lituania 2
TH - Thailandia 2
AL - Albania 1
AZ - Azerbaigian 1
BG - Bulgaria 1
BO - Bolivia 1
DK - Danimarca 1
EC - Ecuador 1
GH - Ghana 1
GR - Grecia 1
HU - Ungheria 1
IE - Irlanda 1
IQ - Iraq 1
JO - Giordania 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LU - Lussemburgo 1
LV - Lettonia 1
MM - Myanmar 1
MO - Macao, regione amministrativa speciale della Cina 1
MX - Messico 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PA - Panama 1
PK - Pakistan 1
PT - Portogallo 1
RS - Serbia 1
SI - Slovenia 1
TN - Tunisia 1
ZA - Sudafrica 1
Totale 5.640
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Città #
Chandler 716
Jacksonville 389
Singapore 317
Princeton 270
New York 235
Nanjing 164
Ann Arbor 117
Dearborn 111
Wilmington 80
Boardman 66
Beijing 57
Nanchang 51
Mountain View 42
Sassari 42
Santa Clara 36
Shenyang 36
Changsha 33
Munich 33
Hebei 32
Woodbridge 30
Brno 29
Norwalk 25
Tianjin 24
Jiaxing 22
Seoul 22
Izmir 21
Kunming 18
Cagliari 16
Ashburn 15
Brussels 15
Guangzhou 14
Hangzhou 13
San Francisco 13
Ningbo 11
Andover 10
Hong Kong 10
Jinan 10
Shanghai 10
Toronto 9
Washington 9
Los Angeles 8
Olomouc 8
West Jordan 8
Zhengzhou 8
Auburn Hills 7
Dallas 7
Frankfurt am Main 7
Gergei 7
Lanzhou 7
Milan 7
Taizhou 7
Helsinki 6
Paris 6
Tappahannock 6
The Dalles 6
Baton Rouge 5
Canberra 5
London 5
Melbourne 5
Ottawa 5
Redwood City 5
Caracas 4
Changchun 4
Haikou 4
Madrid 4
Porto Torres 4
Romola 4
Borne 3
Cairo 3
Chisinau 3
Edinburgh 3
Houston 3
Mirano 3
Naples 3
Rome 3
Shenzhen 3
Sydney 3
Tel Aviv 3
Wuxi 3
Beauharnois 2
Canelli 2
Carlentini 2
Cedar Knolls 2
Erchin 2
Falls Church 2
Furtei 2
Hanover 2
Hefei 2
Indore 2
Markham 2
Montreal 2
Nürnberg 2
Paternò 2
Piacenza 2
Romainville 2
Tallinn 2
Tokyo 2
Vienna 2
Yiwu 2
Alexandria 1
Totale 3.409
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Nome #
Novel docetaxel-loaded nanoparticles based on poly(lactide-co-caprolactone) and poly(lactideco-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies 85
Polymeric Nanoparticles Encapsulating White Tea Extract for Nutraceutical Application 82
Nanoencapsulation of dietary flavonoid fisetin: Formulation and in vitro antioxidant and α-glucosidase inhibition activities 79
Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors 78
Carbonic Anhydrase Inhibition with Benzenesulfonamides and Tetrafluorobenzenesulfonamides Obtained via Click Chemistry. 74
Design, synthesis, molecular modeling and anti-HIV 1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes 72
Ceftriaxone blocks the polymerization of α-synuclein and exerts neuroprotective effects in vitro 68
YB-1 Expression Promotes Epithelial-To-Mesenchymal Transition in Prostate Cancer that is Inhibited by a Small Molecule Fisetin. 68
Synthesis and dopamine D2-like receptor binding affinity of substituted 5-phenyl-pyrrole-3-carboxamides 68
Design and synthesis of novel dihydroxyindole-2-carboxylic acids as HIV-1 integrase inhibitors 67
Effect of chitosan concentration on PLGA microcapsules for controlled release and stability of resveratrol 66
Design and discovery of novel quinazolinedione-based redox modulators as therapies for pancreatic cancer 66
Carbonic Anhydrase I 65
Nanoencapsulation of natural triterpenoid celastrol for prostate cancer treatment 65
POLYMERIC NANOPARTICLES ENCAPSULATING A COMBINATION OF NATURAL BIO-ACTIVES TRANS-RESVERATROL (RSV) AND CELASTROL (CL), A PROCESS FOR THE PREPARATION AND USE THEREOF IN THE TREATMENT OF PROSTATE CANCER 65
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities 64
A versatile salicyl hydrazonic ligand and its metal complexes as antiviral agents 64
Targeted nanoparticles encapsulating (-)-epigallocatechin-3-gallate for prostate cancer prevention and therapy 64
HIV-1 IN strand transfer inhibitors: a focus on metal binding 64
Single amino acid substitution in HIV-1 integrase catalytic core causes a dramatic shift in inhibitor selectivity 63
Mechanistic Evaluation of Sarkostat in Pancreatic Cancer. 62
Antiretroviral activity of metal-chelating HIV-1 integrase inhibitors. 61
Formulation and characterization of Chitosan/PLGA microspheres for controlled release of nutraceutical resveratrol 61
Design and Synthesis of Novel Indole beta-Diketo Acid Derivatives as HIV-1 Integrase Inhibitors 59
Development of polymeric microbubbles targeted to prostate-specific membrane antigen as prototype of novel ultrasound contrast agents 59
Addition reactions of acetylenic esters to 6,7-dihydrobenzo[b]furan-4-(5H)-one, 6,7-dihydroindol-4(5H)-one, 5,6-dihydrobenzo[b]furan-7(6H)-one and 5,6-dihydroindol-7(6H)-one ketoximes. Formation of reduced furo[g]- and pyrrole[g]indoles 59
Benzoxaborole as a new chemotype for carbonic anhydrase inhibition 59
SMALL MOLECULES INDUCERS OFREACTIVE OXYGEN SPECIES AND INHIBITORS OF MITOCHONDRIAL ACTIVITY 58
Design and discovery of novel small molecule modulators of reactive oxygen species-mediated cell signaling 57
Metal-chelating 2-Hydroxyphenyl Amide Pharmacophore for Inhibition of Influenza Virus Endonuclease. 56
DNA Binders: 1. Evaluation of DNA-Interactive Ability, Design, and Synthesis of Novel Intercalating Agents 55
Graphene-containing thermoresponsive nanocomposite hydrogels of poly(N-isopropylacrylamide) prepared by frontal polymerization 55
Design and synthesis of novel dihydroquinoline-3-carboxylic acids as HIV-1 integrase inhibitors 55
Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells 54
Peptidomimetics as Protein Arginine Deiminase 4 (PAD4) Inhibitors 53
DNA Binders: 2. Molecular Recognition of DNA by 2,3,6,7-tetrahydro-1H-pyrrolo[1,2-a]indole-1,8(5H)-dione bis(4,5-dihydro-1H-imidazol-2-ylhydrazone) as a Prototype of “Two-Armed” Intercalating Agents 53
Targeted therapy using nanotechnology: focus on cancer 52
Natural polyphenols for one pot green synthesis and stabilization of gold nanoparticles with antioxidant and biological activities 52
Single-step green synthesis and characterization of gold-conjugated polyphenol nanoparticles with antioxidant and biological activities 52
Design of novel bioisosteres of beta-diketoacid inhibitors of HIV-1 integrase 52
Design and synthesis of bis-amide and hydrazide-containing derivatives of malonic acid as potential HIV-1 integrase inhibitors 51
Design and Synthesis of Novel Polycycles Based on the 3H-pyrrolo/6,7-dihydropyrido[1,2-a]indole scaffold as Templates for Pharmaceutical Development 51
Hyperbranched Molecular Structures with Potential Antiviral Activity: Derivatives of 5,6-Dihydroxyindole-2-Carboxylic Acid 50
Investigation of the salicylaldehyde thiosemicarbazone scaffold for inhibition of influenza virus PA endonuclease 50
N-acylhydrazone inhibitors of influenza virus PA endonuclease with versatile metal binding modes 50
Targeted Nanoparticles for the Delivery of Novel Bioactive Molecules to Pancreatic Cancer Cells 50
Design and discovery of novel small molecule redox modulators as therapies for pancreatic cancer 50
Investigation of furo[2,3-h]- and pyridazino[3,4-f]cinnolin-3-ol scaffolds as substrates for the development of novel HIV-1 integrase inhibitors 50
Design and Synthesis of Novel Reactive Oxygen Species Inducers for the Treatment of Pancreatic Ductal Adenocarcinoma 49
Inhibition of a-class cytosolic human carbonic anhydrases I, II, IX and XII, and b-class fungal enzymes by carboxylic acids and their derivatives: new isoform-I selective nanomolar inhibitors. 48
An integrated biological approach to guide the development of metal-chelating inhibitors of influenza virus PA endonuclease 48
Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors 48
Bisbenzo[g]indoli: sintesi e attività citostatica 47
Role of metals in HIV-1 integrase inhibitor design. Chapter 20 45
Polimeri Iper-Ramificati A Potenziale Attivita' Biologica 45
From Ligand to Complexes: Inhibition of HIV-1 Integrase by β-Diketo Acid Metal Complexes 45
Dietary flavonoid fisetin binds to β-tubulin and disrupts microtubule dynamics in prostate cancer cells 44
Synthesis and in vitro anticancer activity evaluation of biscarbamic esters of 2,3-bis(hydroxymethyl)-1-methyl-7- and 7,8-substituted- benzo[g]indoles 44
Synthesis and D-2-like binding affinity of 4,5-dihydro-1H-benzo[g]indole-3-carboxamide derivatives as conformationally restricted 5-phenyl-pyrrole-3-carboxamide analogs 43
From Ligand to Complexes. Part 2. Remarks on Human Immunodeficiency Virus Type 1 Integrase inhibition by β-Diketo Acid Metal Complexes 43
Discovery of novel functionalized 1,2,4-triazoles as PARP-1 inhibitors in breast cancer: Design, synthesis and antitumor activity evaluation 43
Oxidative stress and mitochondria damage contribute to silica nanoparticle-induced cytotoxicity in human endothelial cells 43
Mutational analysis of the binding pockets of the diketo acid inhibitor L-742,001 in the influenza virus PA endonuclease. 42
Docetaxel-loaded nanoparticles based on PLA-co-caprolactone and PLGA-co-caprolactone for prostate cancer treatment 42
Inhibition of Human Immunodeficiency Virus-1 Integrase by β-Diketo Acid Coated Gold Nanoparticles 42
Synthesis and Evaluation of Different Fatty Acid Esters Formulated into Precirol (R) ATO-Based Lipid Nanoparticles as Vehicles for Topical Delivery 42
Resveratrol-loaded nanoparticles based on poly(epsilon-caprolactone) and poly(D,L-lactic-co-glycolic acid)-poly(ethylene glycol) blend for prostate cancer treatment. 42
Search for the pharmacophore in prazosin for Transport-P 41
Prostate specific membrane antigen (PSMA) targeting nano-EGCG for prostate cancer prevention and treatment 41
Progettazione, sintesi e valutazione preliminare dall'attività intercalante di nuovi derivati"two armed"del 2,3,6,7-tetrahydro-1H-pirrolo[1,2-a]indolo-1,8(5H)-dione 41
Ruthenium Arene Complexes as HIV-1 Integrase Strand Transfer Inhibitors 41
Targeted nanoparticles for the delivery of novel bioactive molecules to pancreatic cancer cells 40
Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture 40
From ligand to complexes: Part 2: Remarks on human immunodeficiency virus type 1 integrase inhibition by beta-diketo acid metal complexes 40
Role of YB-1, a regulator of epithelial to mesenchymal transition, in prostate cancer: Inhibition by a dietary flavonoid fisetin 40
Viral enzymes containing magnesium: metal binding as a successful strategy in drug design 38
Rheological characterization of high graphene loaded thermoplastic and thermoset matrices 38
Synthesis and D2 binding affinity of 4,5-dihydrobenzo[g]indole-3-carboxamides as conformationally restricted phenylpirrole carboxamide analogues 37
Searching for novel carbonic anhydrase inhibitors: from virtual screening to the lab bench 37
Development of novel cationic chitosan-and anionic alginate–coated poly(d,l-lactide-co-glycolide) nanoparticles for controlled release and light protection of resveratrol 37
Evaluation in vitro of new polymeric contrast microbubbles using Qontrast software 36
Tailoring the physical properties of nanocomposite films by the insertion of graphene and other nanoparticles. 36
Piridazine N-ossidi. III. Sintesi e valutazione microbiologica di benzo[f]cinnolin-N-ossidi 35
Valutazione in vitro della riflettività di nuovi prototipi di microbolle a rivestimento polimerico mediante l’impiego del software Qontrast 35
Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features in Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice 34
Nanoparticle therapeutics for prostate cancer treatment. 34
Attività biologica e studi di docking di derivati bis-ammidici dell'acido 5,6- diidrossiindolo-2-carbossilico come inibitori dell'enzima HIV-1 integrasi 34
Virtual screening and biological validation of novel influenza virus PA endonuclease inhibitors 33
A Novel Redox Modulator Induces a GPX4-Mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species 33
Inhibition of human immunodeficiency virus-1 integrase by beta-diketo acids-coated gold nanoparticles 33
Fisetin inhibits human melanoma cell growth through direct binding to p70S6K and mTOR: findings from 3-D melanoma skin equivalents and computational modeling. 32
Virtual Screening-Driven Identification of Human Carbonic Anhydrase Inhibitors incorporating an Original, New Pharmacophore 31
Analisi strutturale retrospettiva e nuova sintesi di derivati del 2-benzoil-4-benzilidene-5-metil-2,4-diidro-3h-pirazol-3-one 31
Structural Investigation of 3,5-Disubstituted Isoxazoles by 1H-Nuclear Magnetic Resonance 30
Targeting HIV-1 Integrase Zinc Binding Motif. Chapter 37 30
Investigating the Role of Metal Chelation in HIV-1 Integrase Strand Transfer Inhibitors 30
Resveratrol nanoformulation for cancer prevention and therapy 29
Nanoparticle therapeutics for prostate cancer treatment. 29
Oxidative stress and mitochondria damage contribute to silica nanoparticle-induced cytotoxicity in human endothelial cells 29
Structure-based drug design e sintesi di nuovi bioisosteri eterociclici della funzione beta-diketoacida come inibitori dell'enzima HIV-1 integrasi 29
Totale 4.912
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Categoria #
all - tutte 33.857
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 33.857
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020666 0 0 0 0 110 97 181 16 111 24 117 10
2020/2021868 101 10 152 3 113 32 128 20 132 128 27 22
2021/2022581 77 10 1 3 4 7 12 28 52 39 67 281
2022/20231.364 178 115 26 221 124 213 12 167 210 7 60 31
2023/2024656 78 29 11 15 290 9 2 26 2 19 46 129
2024/2025596 41 22 278 94 161 0 0 0 0 0 0 0
Totale 5.759