IRIS
SECHI, Mario
 Distribuzione geografica
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Continente #
NA - Nord America 7.277
AS - Asia 4.147
SA - Sud America 2.663
EU - Europa 2.266
AF - Africa 201
OC - Oceania 19
Continente sconosciuto - Info sul continente non disponibili 16
AN - Antartide 1
Totale 16.590
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Nazione #
US - Stati Uniti d'America 7.109
BR - Brasile 2.380
SG - Singapore 1.691
CN - Cina 1.068
UA - Ucraina 653
VN - Vietnam 402
IT - Italia 342
DE - Germania 327
HK - Hong Kong 312
SE - Svezia 197
FR - Francia 183
GB - Regno Unito 146
FI - Finlandia 129
AR - Argentina 107
TR - Turchia 87
BD - Bangladesh 85
IN - India 81
RU - Federazione Russa 74
IQ - Iraq 71
CA - Canada 68
ZA - Sudafrica 66
MX - Messico 60
UZ - Uzbekistan 49
EC - Ecuador 43
JP - Giappone 41
VE - Venezuela 40
CZ - Repubblica Ceca 38
PK - Pakistan 35
SA - Arabia Saudita 35
MA - Marocco 33
ES - Italia 29
PL - Polonia 29
EG - Egitto 28
KR - Corea 28
CO - Colombia 26
JO - Giordania 23
NL - Olanda 20
ID - Indonesia 19
UY - Uruguay 19
AU - Australia 18
BE - Belgio 18
AT - Austria 17
PY - Paraguay 16
PE - Perù 15
TN - Tunisia 15
AZ - Azerbaigian 14
DZ - Algeria 13
IL - Israele 13
KZ - Kazakistan 13
NP - Nepal 12
PA - Panama 12
CL - Cile 10
KE - Kenya 10
SN - Senegal 10
AL - Albania 9
LT - Lituania 9
AO - Angola 8
DO - Repubblica Dominicana 8
KG - Kirghizistan 8
RO - Romania 8
XK - ???statistics.table.value.countryCode.XK??? 8
BO - Bolivia 7
OM - Oman 7
IE - Irlanda 6
AE - Emirati Arabi Uniti 5
EU - Europa 5
IR - Iran 5
PH - Filippine 5
PS - Palestinian Territory 5
BG - Bulgaria 4
ET - Etiopia 4
GR - Grecia 4
HN - Honduras 4
KW - Kuwait 4
LB - Libano 4
NG - Nigeria 4
RS - Serbia 4
SV - El Salvador 4
A2 - ???statistics.table.value.countryCode.A2??? 3
BH - Bahrain 3
CR - Costa Rica 3
GE - Georgia 3
JM - Giamaica 3
MD - Moldavia 3
NI - Nicaragua 3
QA - Qatar 3
TH - Thailandia 3
AM - Armenia 2
BA - Bosnia-Erzegovina 2
BN - Brunei Darussalam 2
BY - Bielorussia 2
CH - Svizzera 2
CI - Costa d'Avorio 2
DK - Danimarca 2
EE - Estonia 2
HU - Ungheria 2
LY - Libia 2
MN - Mongolia 2
MY - Malesia 2
TT - Trinidad e Tobago 2
Totale 16.571
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Città #
Dallas 2.758
Singapore 837
Chandler 716
San Jose 456
Jacksonville 389
Ashburn 322
Hong Kong 309
New York 278
Beijing 270
Princeton 270
Nanjing 167
São Paulo 157
Ho Chi Minh City 141
Lauterbourg 128
Ann Arbor 117
Dearborn 111
Shanghai 97
Hanoi 95
Los Angeles 94
Wilmington 80
Rio de Janeiro 75
Belo Horizonte 71
Boardman 68
Santa Clara 68
Nanchang 51
Sassari 46
Tashkent 46
Mountain View 41
Johannesburg 40
Curitiba 39
Porto Alegre 39
Brasília 38
Tokyo 38
Munich 37
Shenyang 36
Orem 34
Tianjin 34
Changsha 33
Hebei 32
Helsinki 31
The Dalles 31
Woodbridge 30
Brno 29
Council Bluffs 28
Seoul 28
Cagliari 27
San Francisco 27
Warsaw 27
Denver 26
Columbus 25
Norwalk 25
Baghdad 24
Da Nang 24
Stockholm 24
Frankfurt am Main 23
Izmir 23
Poplar 23
Jiaxing 22
Campinas 21
London 21
Toronto 21
Buffalo 20
Osasco 20
Chennai 19
Goiânia 19
Houston 19
Salvador 19
Brooklyn 18
Brussels 18
Chicago 18
Kunming 18
Montreal 18
Ribeirão Preto 18
Amman 17
Carapicuíba 17
Guangzhou 17
Guarulhos 17
Sorocaba 17
Caracas 16
Fortaleza 16
Istanbul 16
Mexico City 16
Montevideo 16
Santo André 16
Biên Hòa 15
Caxias do Sul 15
Dhaka 15
Quito 15
Abbiategrasso 14
Ankara 14
Betim 14
Hangzhou 14
São José dos Campos 14
Baku 13
Cape Town 13
Guayaquil 13
Haiphong 13
Nuremberg 13
Praia Grande 13
Recife 13
Totale 9.844
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Nome #
null 509
Design, anticancer activity, and mechanistic evaluation of a novel class of selective human carbonic anhydrase IX inhibitors featuring a trifluorodihydroxypropanone pharmacophore 245
RNA Nanoparticles Harboring Radioisotopes or Other Imaging Molecules for Spontaneous Tumor Targeting for Early Cancer Diagnosis 209
Addition reactions of acetylenic esters to 6,7-dihydrobenzo[b]furan-4-(5H)-one, 6,7-dihydroindol-4(5H)-one, 5,6-dihydrobenzo[b]furan-7(6H)-one and 5,6-dihydroindol-7(6H)-one ketoximes. Formation of reduced furo[g]- and pyrrole[g]indoles 201
Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors 192
Design and discovery of novel small molecule redox modulators as therapies for pancreatic cancer 188
SMALL MOLECULES INDUCERS OFREACTIVE OXYGEN SPECIES AND INHIBITORS OF MITOCHONDRIAL ACTIVITY 184
Design and discovery of novel quinazolinedione-based redox modulators as therapies for pancreatic cancer 183
POLYMERIC NANOPARTICLES ENCAPSULATING A COMBINATION OF NATURAL BIO-ACTIVES TRANS-RESVERATROL (RSV) AND CELASTROL (CL), A PROCESS FOR THE PREPARATION AND USE THEREOF IN THE TREATMENT OF PROSTATE CANCER 178
A versatile salicyl hydrazonic ligand and its metal complexes as antiviral agents 178
Benzoxaborole as a new chemotype for carbonic anhydrase inhibition 178
Carbonic Anhydrase I 174
Design and synthesis of novel dihydroxyindole-2-carboxylic acids as HIV-1 integrase inhibitors 172
Ceftriaxone blocks the polymerization of α-synuclein and exerts neuroprotective effects in vitro 170
Carbonic Anhydrase Inhibition with Benzenesulfonamides and Tetrafluorobenzenesulfonamides Obtained via Click Chemistry. 168
Novel docetaxel-loaded nanoparticles based on poly(lactide-co-caprolactone) and poly(lactideco-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies 164
Graphene-containing thermoresponsive nanocomposite hydrogels of poly(N-isopropylacrylamide) prepared by frontal polymerization 163
Design and discovery of novel small molecule modulators of reactive oxygen species-mediated cell signaling 158
Design and synthesis of bis-amide and hydrazide-containing derivatives of malonic acid as potential HIV-1 integrase inhibitors 158
Attività biologica e studi di docking di derivati bis-ammidici dell'acido 5,6- diidrossiindolo-2-carbossilico come inibitori dell'enzima HIV-1 integrasi 155
Design and synthesis of novel dihydroquinoline-3-carboxylic acids as HIV-1 integrase inhibitors 153
Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture 148
Analisi strutturale retrospettiva e nuova sintesi di derivati del 2-benzoil-4-benzilidene-5-metil-2,4-diidro-3h-pirazol-3-one 146
HIV-1 IN strand transfer inhibitors: a focus on metal binding 145
Bisbenzo[g]indoli: sintesi e attività citostatica 141
Single-step green synthesis and characterization of gold-conjugated polyphenol nanoparticles with antioxidant and biological activities 141
Antiretroviral activity of metal-chelating HIV-1 integrase inhibitors. 140
N-acylhydrazone inhibitors of influenza virus PA endonuclease with versatile metal binding modes 140
Progettazione, sintesi e valutazione preliminare dall'attività intercalante di nuovi derivati"two armed"del 2,3,6,7-tetrahydro-1H-pirrolo[1,2-a]indolo-1,8(5H)-dione 140
DNA Binders: 2. Molecular Recognition of DNA by 2,3,6,7-tetrahydro-1H-pyrrolo[1,2-a]indole-1,8(5H)-dione bis(4,5-dihydro-1H-imidazol-2-ylhydrazone) as a Prototype of “Two-Armed” Intercalating Agents 138
Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors 138
Structure-based drug design e sintesi di nuovi bioisosteri eterociclici della funzione beta-diketoacida come inibitori dell'enzima HIV-1 integrasi 136
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities 135
Inhibition of Human Immunodeficiency Virus-1 Integrase by β-Diketo Acid Coated Gold Nanoparticles 135
Design and synthesis of novel DNA binders 135
Small molecule inducers of reactive oxygen species and inhibitors of mitochondrial activity 134
Searching for novel carbonic anhydrase inhibitors: from virtual screening to the lab bench 134
YB-1 Expression Promotes Epithelial-To-Mesenchymal Transition in Prostate Cancer that is Inhibited by a Small Molecule Fisetin. 133
An integrated biological approach to guide the development of metal-chelating inhibitors of influenza virus PA endonuclease 133
Design and Synthesis of Novel Polycycles Based on the 3H-pyrrolo/6,7-dihydropyrido[1,2-a]indole scaffold as Templates for Pharmaceutical Development 133
A Novel Redox Modulator Induces a GPX4-Mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species 132
Ricerca di nuovi inibitori selettivi dell'HIV-1 integrasi 131
Comparative efficacy of epigallocatechin gallate and its nano-formulation in prostate cancer 3D spheroids model 129
Il "Relaxed complex method" nello studio dell'interazione ligando-DNA 128
Nanoencapsulation of dietary flavonoid fisetin: Formulation and in vitro antioxidant and α-glucosidase inhibition activities 128
Development of polymeric microbubbles targeted to prostate-specific membrane antigen as prototype of novel ultrasound contrast agents 127
Investigation of the salicylaldehyde thiosemicarbazone scaffold for inhibition of influenza virus PA endonuclease 127
Design and synthesis of bis-amide and hydrazide-containing derivatives of malonic acid as potential HIV-1 integrase inhibitors 127
Discovery of novel functionalized 1,2,4-triazoles as PARP-1 inhibitors in breast cancer: Design, synthesis and antitumor activity evaluation 125
Single amino acid substitution in HIV-1 integrase catalytic core causes a dramatic shift in inhibitor selectivity 124
Synthesis and Evaluation of Different Fatty Acid Esters Formulated into Precirol (R) ATO-Based Lipid Nanoparticles as Vehicles for Topical Delivery 123
Effect of chitosan concentration on PLGA microcapsules for controlled release and stability of resveratrol 122
Inhibition of a-class cytosolic human carbonic anhydrases I, II, IX and XII, and b-class fungal enzymes by carboxylic acids and their derivatives: new isoform-I selective nanomolar inhibitors. 121
Polymeric Nanoparticles Encapsulating White Tea Extract for Nutraceutical Application 121
Synthesis and in vitro anticancer activity evaluation of biscarbamic esters of 2,3-bis(hydroxymethyl)-1-methyl-7- and 7,8-substituted- benzo[g]indoles 120
Synthesis and dopamine D2-like receptor binding affinity of substituted 5-phenyl-pyrrole-3-carboxamides 119
Investigation of furo[2,3-h]- and pyridazino[3,4-f]cinnolin-3-ol scaffolds as substrates for the development of novel HIV-1 integrase inhibitors 119
Synthesis of pyrrolo[1,2-a]indole-1,8(5H)-diones as new synthons for developing novel tricyclic compounds of pharmaceutical interest 118
Design, synthesis, molecular modeling and anti-HIV 1 integrase activity of a series of photoactivable diketo acid-containing inhibitors as affinity probes 118
Interaction Studies between Carbonic Anhydrase and a Sulfonamide Inhibitor by Experimental and Theoretical Approaches 117
Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells 117
Novel docetaxel-loaded nanoparticles based on poly(lactide-co-caprolactone) and poly(lactide-co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies 117
Docking ligando-DNA e validazione della capacità intercalante di nuovi derivati "two-armed" 116
Formulation and characterization of Chitosan/PLGA microspheres for controlled release of nutraceutical resveratrol 116
Targeted therapy using nanotechnology: focus on cancer 115
Design, synthesis, molecular modeling and anti-HIV 1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes 115
Design and Synthesis of Novel Reactive Oxygen Species Inducers for the Treatment of Pancreatic Ductal Adenocarcinoma 112
Docetaxel-loaded nanoparticles based on PLA-co-caprolactone and PLGA-co-caprolactone for prostate cancer treatment 111
Development of novel cationic chitosan-and anionic alginate–coated poly(d,l-lactide-co-glycolide) nanoparticles for controlled release and light protection of resveratrol 111
Nanoencapsulation of natural triterpenoid celastrol for prostate cancer treatment 109
Rheological characterization of high graphene loaded thermoplastic and thermoset matrices 109
Hyperbranched Molecular Structures with Potential Antiviral Activity: Derivatives of 5,6-Dihydroxyindole-2-Carboxylic Acid 106
Natural polyphenols for one pot green synthesis and stabilization of gold nanoparticles with antioxidant and biological activities 106
Development of (−)-epigallocatechin-3-gallate-loaded folate receptor-targeted nanoparticles for prostate cancer treatment 104
From ligand to complexes: Part 2: Remarks on human immunodeficiency virus type 1 integrase inhibition by beta-diketo acid metal complexes 104
Targeted Nanoparticles for the Delivery of Novel Bioactive Molecules to Pancreatic Cancer Cells 103
DNA Binders: 1. Evaluation of DNA-Interactive Ability, Design, and Synthesis of Novel Intercalating Agents 102
Mechanistic Evaluation of Sarkostat in Pancreatic Cancer. 101
Resveratrol nanoformulation for cancer prevention and therapy 100
Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features in Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice 99
Oxidative stress and mitochondria damage contribute to silica nanoparticle-induced cytotoxicity in human endothelial cells 99
From Ligand to Complexes: Inhibition of HIV-1 Integrase by β-Diketo Acid Metal Complexes 99
Design and Synthesis of Novel Indole beta-Diketo Acid Derivatives as HIV-1 Integrase Inhibitors 98
Evaluation in vitro of new polymeric contrast microbubbles using Qontrast software 98
Ruthenium Arene Complexes as HIV-1 Integrase Strand Transfer Inhibitors 98
Polimeri Iper-Ramificati A Potenziale Attivita' Biologica 98
Prostate specific membrane antigen (PSMA) targeting nano-EGCG for prostate cancer prevention and treatment 96
Nanoparticle therapeutics for prostate cancer treatment. 96
Targeted nanoparticles encapsulating (-)-epigallocatechin-3-gallate for prostate cancer prevention and therapy 96
Targeted nanoparticles for the delivery of novel bioactive molecules to pancreatic cancer cells 95
Design of novel bioisosteres of beta-diketoacid inhibitors of HIV-1 integrase 95
Studi strutturistici di isossazoli 3,5-disostituiti mediante spettroscopia1H-NMR 94
Studi su indoli Beta-dichetoacidi come inibitori dell'HIV-1 integrasi: progettazione, sintesi, studi SAR, cristallografia e docking 94
Viral enzymes containing magnesium: metal binding as a successful strategy in drug design 93
Tailoring the physical properties of nanocomposite films by the insertion of graphene and other nanoparticles. 93
Valutazione in vitro della riflettività di nuovi prototipi di microbolle a rivestimento polimerico mediante l’impiego del software Qontrast 93
Peptidomimetics as Protein Arginine Deiminase 4 (PAD4) Inhibitors 92
The "Click-tail approach" for the design and synthesis of novel carbonic anhydrase inhibitors 92
Natural polyphenols for one pot green synthesis and stabilization of gold nanoparticles with antioxidant activity 92
Identification of new fisetin analogs as kinase inhibitors: Data on synthesis and anti-skin cancer activities evaluation 91
Totale 13.256
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Categoria #
all - tutte 62.636
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 62.636
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021177 0 0 0 0 0 0 0 0 0 128 27 22
2021/2022581 77 10 1 3 4 7 12 28 52 39 67 281
2022/20231.359 178 115 26 221 123 212 12 167 210 7 58 30
2023/2024651 77 29 11 15 289 9 2 26 2 19 45 127
2024/20254.589 41 22 277 94 178 137 240 995 1.682 600 205 118
2025/20266.985 328 1.427 1.779 1.044 600 388 819 182 241 177 0 0
Totale 16.727