IRIS
SECHI, Mario
 Distribuzione geografica
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Continente #
NA - Nord America 2.771
EU - Europa 1.542
AS - Asia 724
OC - Oceania 16
AF - Africa 14
SA - Sud America 9
Continente sconosciuto - Info sul continente non disponibili 8
Totale 5.084
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Nazione #
US - Stati Uniti d'America 2.753
UA - Ucraina 633
CN - Cina 513
DE - Germania 247
IT - Italia 207
SE - Svezia 174
SG - Singapore 103
FI - Finlandia 98
GB - Regno Unito 61
CZ - Repubblica Ceca 37
FR - Francia 33
TR - Turchia 24
SA - Arabia Saudita 23
KR - Corea 22
CA - Canada 16
AU - Australia 15
BE - Belgio 14
HK - Hong Kong 12
EG - Egitto 8
IN - India 7
ES - Italia 6
EU - Europa 5
NL - Olanda 5
IL - Israele 4
VE - Venezuela 4
A2 - ???statistics.table.value.countryCode.A2??? 3
IR - Iran 3
MA - Marocco 3
MD - Moldavia 3
QA - Qatar 3
RO - Romania 3
RU - Federazione Russa 3
AR - Argentina 2
AT - Austria 2
BR - Brasile 2
CH - Svizzera 2
EE - Estonia 2
JP - Giappone 2
TH - Thailandia 2
AL - Albania 1
BD - Bangladesh 1
BG - Bulgaria 1
DK - Danimarca 1
EC - Ecuador 1
GH - Ghana 1
GR - Grecia 1
HU - Ungheria 1
IE - Irlanda 1
IQ - Iraq 1
LA - Repubblica Popolare Democratica del Laos 1
LT - Lituania 1
LU - Lussemburgo 1
LV - Lettonia 1
MM - Myanmar 1
MO - Macao, regione amministrativa speciale della Cina 1
MX - Messico 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PA - Panama 1
PT - Portogallo 1
RS - Serbia 1
SI - Slovenia 1
TN - Tunisia 1
ZA - Sudafrica 1
Totale 5.084
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Città #
Chandler 716
Jacksonville 389
Princeton 270
New York 235
Nanjing 164
Ann Arbor 117
Dearborn 111
Wilmington 80
Boardman 66
Singapore 63
Nanchang 51
Beijing 50
Mountain View 42
Sassari 42
Shenyang 36
Changsha 33
Hebei 32
Woodbridge 30
Brno 29
Norwalk 25
Tianjin 24
Seoul 22
Izmir 21
Jiaxing 21
Kunming 18
Cagliari 16
Munich 16
Ashburn 15
Brussels 14
Hangzhou 13
San Francisco 13
Guangzhou 11
Ningbo 11
Andover 10
Hong Kong 10
Jinan 10
Washington 9
Olomouc 8
West Jordan 8
Auburn Hills 7
Gergei 7
Lanzhou 7
Los Angeles 7
Toronto 7
Zhengzhou 7
Paris 6
Taizhou 6
Tappahannock 6
The Dalles 6
Baton Rouge 5
Canberra 5
Helsinki 5
Melbourne 5
Redwood City 5
Caracas 4
Changchun 4
Frankfurt am Main 4
Haikou 4
Madrid 4
Porto Torres 4
Borne 3
Cairo 3
Chisinau 3
Edinburgh 3
Houston 3
Mirano 3
Naples 3
Rome 3
Sydney 3
Tel Aviv 3
Beauharnois 2
Canelli 2
Carlentini 2
Cedar Knolls 2
Dallas 2
Erchin 2
Falls Church 2
Furtei 2
Hanover 2
Hefei 2
Indore 2
London 2
Markham 2
Montreal 2
Nürnberg 2
Paternò 2
Piacenza 2
Romainville 2
Shanghai 2
Tallinn 2
Tokyo 2
Vienna 2
Alexandria 1
Augusta 1
Baghdad 1
Baotou 1
Belgrade 1
Bologna 1
Borås 1
Botataung 1
Totale 3.048
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Nome #
Novel docetaxel-loaded nanoparticles based on poly(lactide-co-caprolactone) and poly(lactideco-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies 83
Polymeric Nanoparticles Encapsulating White Tea Extract for Nutraceutical Application 78
Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors 74
Carbonic Anhydrase Inhibition with Benzenesulfonamides and Tetrafluorobenzenesulfonamides Obtained via Click Chemistry. 72
Nanoencapsulation of dietary flavonoid fisetin: Formulation and in vitro antioxidant and α-glucosidase inhibition activities 72
Synthesis and dopamine D2-like receptor binding affinity of substituted 5-phenyl-pyrrole-3-carboxamides 67
Effect of chitosan concentration on PLGA microcapsules for controlled release and stability of resveratrol 65
YB-1 Expression Promotes Epithelial-To-Mesenchymal Transition in Prostate Cancer that is Inhibited by a Small Molecule Fisetin. 63
Nanoencapsulation of natural triterpenoid celastrol for prostate cancer treatment 63
HIV-1 IN strand transfer inhibitors: a focus on metal binding 61
Design and synthesis of novel dihydroxyindole-2-carboxylic acids as HIV-1 integrase inhibitors 61
Targeted nanoparticles encapsulating (-)-epigallocatechin-3-gallate for prostate cancer prevention and therapy 60
Ceftriaxone blocks the polymerization of α-synuclein and exerts neuroprotective effects in vitro 59
Single amino acid substitution in HIV-1 integrase catalytic core causes a dramatic shift in inhibitor selectivity 59
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities 59
Mechanistic Evaluation of Sarkostat in Pancreatic Cancer. 58
Carbonic Anhydrase I 57
POLYMERIC NANOPARTICLES ENCAPSULATING A COMBINATION OF NATURAL BIO-ACTIVES TRANS-RESVERATROL (RSV) AND CELASTROL (CL), A PROCESS FOR THE PREPARATION AND USE THEREOF IN THE TREATMENT OF PROSTATE CANCER 57
Design and discovery of novel quinazolinedione-based redox modulators as therapies for pancreatic cancer 57
Formulation and characterization of Chitosan/PLGA microspheres for controlled release of nutraceutical resveratrol 56
Antiretroviral activity of metal-chelating HIV-1 integrase inhibitors. 55
Design and discovery of novel small molecule modulators of reactive oxygen species-mediated cell signaling 55
A versatile salicyl hydrazonic ligand and its metal complexes as antiviral agents 55
Metal-chelating 2-Hydroxyphenyl Amide Pharmacophore for Inhibition of Influenza Virus Endonuclease. 54
Design and Synthesis of Novel Indole beta-Diketo Acid Derivatives as HIV-1 Integrase Inhibitors 54
Development of polymeric microbubbles targeted to prostate-specific membrane antigen as prototype of novel ultrasound contrast agents 54
Benzoxaborole as a new chemotype for carbonic anhydrase inhibition 54
DNA Binders: 1. Evaluation of DNA-Interactive Ability, Design, and Synthesis of Novel Intercalating Agents 53
Design, synthesis, molecular modeling and anti-HIV 1 integrase activity of a series of photoactivatable diketo acid-containing inhibitors as affinity probes 52
SMALL MOLECULES INDUCERS OFREACTIVE OXYGEN SPECIES AND INHIBITORS OF MITOCHONDRIAL ACTIVITY 51
Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells 50
Design of novel bioisosteres of beta-diketoacid inhibitors of HIV-1 integrase 50
Graphene-containing thermoresponsive nanocomposite hydrogels of poly(N-isopropylacrylamide) prepared by frontal polymerization 50
Design and synthesis of novel dihydroquinoline-3-carboxylic acids as HIV-1 integrase inhibitors 50
Single-step green synthesis and characterization of gold-conjugated polyphenol nanoparticles with antioxidant and biological activities 49
Addition reactions of acetylenic esters to 6,7-dihydrobenzo[b]furan-4-(5H)-one, 6,7-dihydroindol-4(5H)-one, 5,6-dihydrobenzo[b]furan-7(6H)-one and 5,6-dihydroindol-7(6H)-one ketoximes. Formation of reduced furo[g]- and pyrrole[g]indoles 49
DNA Binders: 2. Molecular Recognition of DNA by 2,3,6,7-tetrahydro-1H-pyrrolo[1,2-a]indole-1,8(5H)-dione bis(4,5-dihydro-1H-imidazol-2-ylhydrazone) as a Prototype of “Two-Armed” Intercalating Agents 48
Targeted Nanoparticles for the Delivery of Novel Bioactive Molecules to Pancreatic Cancer Cells 48
Hyperbranched Molecular Structures with Potential Antiviral Activity: Derivatives of 5,6-Dihydroxyindole-2-Carboxylic Acid 47
Natural polyphenols for one pot green synthesis and stabilization of gold nanoparticles with antioxidant and biological activities 47
Design and Synthesis of Novel Reactive Oxygen Species Inducers for the Treatment of Pancreatic Ductal Adenocarcinoma 47
Design and synthesis of bis-amide and hydrazide-containing derivatives of malonic acid as potential HIV-1 integrase inhibitors 47
Inhibition of a-class cytosolic human carbonic anhydrases I, II, IX and XII, and b-class fungal enzymes by carboxylic acids and their derivatives: new isoform-I selective nanomolar inhibitors. 46
Investigation of the salicylaldehyde thiosemicarbazone scaffold for inhibition of influenza virus PA endonuclease 46
Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors 46
Design and Synthesis of Novel Polycycles Based on the 3H-pyrrolo/6,7-dihydropyrido[1,2-a]indole scaffold as Templates for Pharmaceutical Development 46
Design and discovery of novel small molecule redox modulators as therapies for pancreatic cancer 46
Investigation of furo[2,3-h]- and pyridazino[3,4-f]cinnolin-3-ol scaffolds as substrates for the development of novel HIV-1 integrase inhibitors 46
Peptidomimetics as Protein Arginine Deiminase 4 (PAD4) Inhibitors 45
N-acylhydrazone inhibitors of influenza virus PA endonuclease with versatile metal binding modes 45
An integrated biological approach to guide the development of metal-chelating inhibitors of influenza virus PA endonuclease 44
Bisbenzo[g]indoli: sintesi e attività citostatica 43
Role of metals in HIV-1 integrase inhibitor design. Chapter 20 42
From Ligand to Complexes: Inhibition of HIV-1 Integrase by β-Diketo Acid Metal Complexes 42
Dietary flavonoid fisetin binds to β-tubulin and disrupts microtubule dynamics in prostate cancer cells 41
From Ligand to Complexes. Part 2. Remarks on Human Immunodeficiency Virus Type 1 Integrase inhibition by β-Diketo Acid Metal Complexes 40
Mutational analysis of the binding pockets of the diketo acid inhibitor L-742,001 in the influenza virus PA endonuclease. 40
Inhibition of Human Immunodeficiency Virus-1 Integrase by β-Diketo Acid Coated Gold Nanoparticles 40
Oxidative stress and mitochondria damage contribute to silica nanoparticle-induced cytotoxicity in human endothelial cells 40
Synthesis and D-2-like binding affinity of 4,5-dihydro-1H-benzo[g]indole-3-carboxamide derivatives as conformationally restricted 5-phenyl-pyrrole-3-carboxamide analogs 39
Prostate specific membrane antigen (PSMA) targeting nano-EGCG for prostate cancer prevention and treatment 39
Progettazione, sintesi e valutazione preliminare dall'attività intercalante di nuovi derivati"two armed"del 2,3,6,7-tetrahydro-1H-pirrolo[1,2-a]indolo-1,8(5H)-dione 39
Resveratrol-loaded nanoparticles based on poly(epsilon-caprolactone) and poly(D,L-lactic-co-glycolic acid)-poly(ethylene glycol) blend for prostate cancer treatment. 39
Docetaxel-loaded nanoparticles based on PLA-co-caprolactone and PLGA-co-caprolactone for prostate cancer treatment 38
Polimeri Iper-Ramificati A Potenziale Attivita' Biologica 38
Synthesis and Evaluation of Different Fatty Acid Esters Formulated into Precirol (R) ATO-Based Lipid Nanoparticles as Vehicles for Topical Delivery 38
From ligand to complexes: Part 2: Remarks on human immunodeficiency virus type 1 integrase inhibition by beta-diketo acid metal complexes 38
Role of YB-1, a regulator of epithelial to mesenchymal transition, in prostate cancer: Inhibition by a dietary flavonoid fisetin 38
Search for the pharmacophore in prazosin for Transport-P 37
Discovery of novel functionalized 1,2,4-triazoles as PARP-1 inhibitors in breast cancer: Design, synthesis and antitumor activity evaluation 37
Synthesis and in vitro anticancer activity evaluation of biscarbamic esters of 2,3-bis(hydroxymethyl)-1-methyl-7- and 7,8-substituted- benzo[g]indoles 37
Ruthenium Arene Complexes as HIV-1 Integrase Strand Transfer Inhibitors 37
Development of a Raltegravir-based Photoaffinity-Labeled Probe for Human Immunodeficiency Virus-1 Integrase Capture 35
Development of novel cationic chitosan-and anionic alginate–coated poly(d,l-lactide-co-glycolide) nanoparticles for controlled release and light protection of resveratrol 35
Targeted therapy using nanotechnology: focus on cancer 34
Synthesis and D2 binding affinity of 4,5-dihydrobenzo[g]indole-3-carboxamides as conformationally restricted phenylpirrole carboxamide analogues 34
Viral enzymes containing magnesium: metal binding as a successful strategy in drug design 33
Tailoring the physical properties of nanocomposite films by the insertion of graphene and other nanoparticles. 33
Searching for novel carbonic anhydrase inhibitors: from virtual screening to the lab bench 33
Rheological characterization of high graphene loaded thermoplastic and thermoset matrices 33
Piridazine N-ossidi. III. Sintesi e valutazione microbiologica di benzo[f]cinnolin-N-ossidi 32
Virtual screening and biological validation of novel influenza virus PA endonuclease inhibitors 32
Valutazione in vitro della riflettività di nuovi prototipi di microbolle a rivestimento polimerico mediante l’impiego del software Qontrast 32
Targeted nanoparticles for the delivery of novel bioactive molecules to pancreatic cancer cells 30
Nanoparticle therapeutics for prostate cancer treatment. 30
Attività biologica e studi di docking di derivati bis-ammidici dell'acido 5,6- diidrossiindolo-2-carbossilico come inibitori dell'enzima HIV-1 integrasi 30
Fisetin inhibits human melanoma cell growth through direct binding to p70S6K and mTOR: findings from 3-D melanoma skin equivalents and computational modeling. 30
Inhibition of human immunodeficiency virus-1 integrase by beta-diketo acids-coated gold nanoparticles 30
Evaluation in vitro of new polymeric contrast microbubbles using Qontrast software 29
Virtual Screening-Driven Identification of Human Carbonic Anhydrase Inhibitors incorporating an Original, New Pharmacophore 29
Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features in Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice 29
Structural Investigation of 3,5-Disubstituted Isoxazoles by 1H-Nuclear Magnetic Resonance 28
Targeting HIV-1 Integrase Zinc Binding Motif. Chapter 37 28
Nanoparticle therapeutics for prostate cancer treatment. 27
Structure-based drug design e sintesi di nuovi bioisosteri eterociclici della funzione beta-diketoacida come inibitori dell'enzima HIV-1 integrasi 27
Docking ligando-DNA e validazione della capacità intercalante di nuovi derivati "two-armed" 27
Investigating the Role of Metal Chelation in HIV-1 Integrase Strand Transfer Inhibitors 27
Resveratrol nanoformulation for cancer prevention and therapy 26
Oxidative stress and mitochondria damage contribute to silica nanoparticle-induced cytotoxicity in human endothelial cells 26
A Novel Redox Modulator Induces a GPX4-Mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species 26
Totale 4.477
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Categoria #
all - tutte 27.469
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 27.469
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.062 273 18 101 4 110 97 181 16 111 24 117 10
2020/2021868 101 10 152 3 113 32 128 20 132 128 27 22
2021/2022581 77 10 1 3 4 7 12 28 52 39 67 281
2022/20231.364 178 115 26 221 124 213 12 167 210 7 60 31
2023/2024656 78 29 11 15 290 9 2 26 2 19 46 129
2024/202539 39 0 0 0 0 0 0 0 0 0 0 0
Totale 5.202