This invention is in the field of medicinal chemistry. In particular, the invention relates to a new classe of small molecules having a quinazolinedione structure with function as reactive oxygen species (ROS) inducers and inhibitors of mitochondrial activity within cancer cells (e.g. pancreatic cancer cells), and their use as therapeutics for the treatment of cancer (e.g. pancreatic cancer) and other diseases.

SMALL MOLECULES INDUCERS OFREACTIVE OXYGEN SPECIES AND INHIBITORS OF MITOCHONDRIAL ACTIVITY / Neamati, Nouri; Sechi, Mario. - (2017).

SMALL MOLECULES INDUCERS OFREACTIVE OXYGEN SPECIES AND INHIBITORS OF MITOCHONDRIAL ACTIVITY

SECHI Mario
2017-01-01

Abstract

This invention is in the field of medicinal chemistry. In particular, the invention relates to a new classe of small molecules having a quinazolinedione structure with function as reactive oxygen species (ROS) inducers and inhibitors of mitochondrial activity within cancer cells (e.g. pancreatic cancer cells), and their use as therapeutics for the treatment of cancer (e.g. pancreatic cancer) and other diseases.
2017
SMALL MOLECULES INDUCERS OFREACTIVE OXYGEN SPECIES AND INHIBITORS OF MITOCHONDRIAL ACTIVITY / Neamati, Nouri; Sechi, Mario. - (2017).
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/240781
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact