In the search of new HIV-1 integrase (IN) inhibitors, we synthesized a series of multimeric 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives. Preliminary results indicate that hyperbranched architectures could represent a peculiar molecular requisite for the development of new antiviral lead compounds

In the search of new HIV-1 integrase (IN) inhibitors, we synthesized a series of multimeric 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives. Preliminary results indicate that hyperbranched architectures could represent a peculiar molecular requisite for the development of new antiviral lead compounds.

Hyperbranched Molecular Structures with Potential Antiviral Activity: Derivatives of 5,6-Dihydroxyindole-2-Carboxylic Acid / Sechi, Mario; Casu, F; Campesi, Ilaria; Fiori, S; Mariani, Alberto. - In: MOLECULES. - ISSN 1420-3049. - 11:12(2006), pp. 968-977. [10.3390/11120968]

Hyperbranched Molecular Structures with Potential Antiviral Activity: Derivatives of 5,6-Dihydroxyindole-2-Carboxylic Acid

SECHI, Mario;CAMPESI, Ilaria;MARIANI, Alberto
2006-01-01

Abstract

In the search of new HIV-1 integrase (IN) inhibitors, we synthesized a series of multimeric 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives. Preliminary results indicate that hyperbranched architectures could represent a peculiar molecular requisite for the development of new antiviral lead compounds
2006
In the search of new HIV-1 integrase (IN) inhibitors, we synthesized a series of multimeric 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives. Preliminary results indicate that hyperbranched architectures could represent a peculiar molecular requisite for the development of new antiviral lead compounds.
Hyperbranched Molecular Structures with Potential Antiviral Activity: Derivatives of 5,6-Dihydroxyindole-2-Carboxylic Acid / Sechi, Mario; Casu, F; Campesi, Ilaria; Fiori, S; Mariani, Alberto. - In: MOLECULES. - ISSN 1420-3049. - 11:12(2006), pp. 968-977. [10.3390/11120968]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/46961
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