IRIS
PASCALE, Rosa Maria
 Distribuzione geografica
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Continente #
NA - Nord America 7.047
AS - Asia 4.537
EU - Europa 2.609
SA - Sud America 2.304
AF - Africa 160
OC - Oceania 16
Continente sconosciuto - Info sul continente non disponibili 13
Totale 16.686
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Nazione #
US - Stati Uniti d'America 6.867
BR - Brasile 2.063
SG - Singapore 1.822
CN - Cina 1.426
UA - Ucraina 828
DE - Germania 372
HK - Hong Kong 317
SE - Svezia 301
VN - Vietnam 301
FR - Francia 251
IT - Italia 247
GB - Regno Unito 165
FI - Finlandia 153
TR - Turchia 134
IN - India 84
IQ - Iraq 80
CA - Canada 74
AR - Argentina 71
MX - Messico 56
CZ - Repubblica Ceca 52
ZA - Sudafrica 50
BD - Bangladesh 49
RU - Federazione Russa 49
UZ - Uzbekistan 42
PK - Pakistan 41
BE - Belgio 40
VE - Venezuela 38
EC - Ecuador 35
ID - Indonesia 32
MA - Marocco 30
JP - Giappone 28
AT - Austria 26
CO - Colombia 26
ES - Italia 22
KR - Corea 21
PL - Polonia 21
PY - Paraguay 21
IR - Iran 20
AE - Emirati Arabi Uniti 19
JO - Giordania 18
LT - Lituania 15
SA - Arabia Saudita 15
TN - Tunisia 15
AU - Australia 14
UY - Uruguay 14
CL - Cile 13
AZ - Azerbaigian 12
NL - Olanda 12
PE - Perù 12
SN - Senegal 12
EU - Europa 11
KE - Kenya 11
NP - Nepal 11
PA - Panama 11
BO - Bolivia 9
DZ - Algeria 9
JM - Giamaica 9
BG - Bulgaria 8
HN - Honduras 8
IL - Israele 7
OM - Oman 7
PH - Filippine 7
RO - Romania 7
EG - Egitto 6
KZ - Kazakistan 6
CI - Costa d'Avorio 5
DO - Repubblica Dominicana 5
ET - Etiopia 5
MY - Malesia 5
SY - Repubblica araba siriana 5
AO - Angola 4
EE - Estonia 4
KG - Kirghizistan 4
NG - Nigeria 4
NI - Nicaragua 4
PS - Palestinian Territory 4
RS - Serbia 4
AL - Albania 3
AM - Armenia 3
BA - Bosnia-Erzegovina 3
CG - Congo 3
CH - Svizzera 3
CR - Costa Rica 3
DK - Danimarca 3
LB - Libano 3
PT - Portogallo 3
QA - Qatar 3
SV - El Salvador 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BH - Bahrain 2
BN - Brunei Darussalam 2
BW - Botswana 2
BY - Bielorussia 2
GE - Georgia 2
HU - Ungheria 2
IE - Irlanda 2
LV - Lettonia 2
MD - Moldavia 2
ML - Mali 2
NZ - Nuova Zelanda 2
Totale 16.663
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Città #
Dallas 2.026
Singapore 1.038
Chandler 955
Jacksonville 489
San Jose 423
Hong Kong 312
Ashburn 296
Beijing 282
Princeton 272
Dearborn 200
Nanjing 198
Ann Arbor 165
São Paulo 151
Wilmington 137
Sassari 128
Lauterbourg 126
Ho Chi Minh City 109
Nanchang 101
Los Angeles 95
Shanghai 95
Boardman 90
Rio de Janeiro 83
Hanoi 77
Izmir 76
Santa Clara 68
Tianjin 56
Changsha 53
Woodbridge 53
Shenyang 52
New York 51
Council Bluffs 48
Belo Horizonte 46
Brno 45
Munich 41
Brussels 40
The Dalles 40
Tashkent 39
Hebei 38
Jinan 38
Baghdad 36
Columbus 35
Toronto 35
Orem 34
Brasília 33
Jiaxing 32
Norwalk 30
Falls Church 29
London 28
Campinas 27
Helsinki 27
Tokyo 27
Zhengzhou 27
Porto Alegre 26
Hangzhou 25
Guangzhou 24
Johannesburg 24
Ningbo 24
Chennai 22
Mountain View 22
Nuremberg 22
Buffalo 21
Curitiba 21
Ribeirão Preto 21
Boston 20
San Francisco 20
Seoul 20
Warsaw 20
Andover 19
Brooklyn 19
Denver 19
Augusta 18
Goiânia 18
Kunming 18
Stockholm 18
Amman 17
Frankfurt am Main 17
Guarulhos 17
Salvador 17
San Mateo 17
Leawood 16
Montreal 16
Atlanta 15
Fortaleza 15
Praia Grande 15
Santo André 15
Ardabil 14
Houston 14
Mexico City 14
Ankara 13
Chicago 13
Dhaka 13
Guayaquil 13
Mumbai 13
Taizhou 13
Aracaju 12
Baku 12
Casablanca 12
Da Nang 12
Erbil 12
Istanbul 12
Totale 9.862
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Nome #
A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis 343
Alterations of methionine metabolism in hepatocarcinogenesis: the emergent role of glycine N-methyltransferase in liver injury 230
An expression signature of phenotipic resistance to hepatocellular carcinoma identified by cross-species gene expression analysis 215
1-5-formyltetrahydrofolate and 1-5-methyltetrahydrofolate rescue in L-1210 leukemia treated with high methotrexate doses 214
5' Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon tetrachloride intoxication 202
Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans 190
Chemoprevention of rat liver carcinogenesis by S-adenosyl-L-methionine: a long-term study. 186
Cell cycle deregulation in liver lesions of rats with and without genetic predisposition to hepatocarcinogenesis 184
. Chemoprevention by S-adenosyl-L-methionine of rat liver carcinogenesis initiated by 1,2-dimethylhydrazine and promoted by orotic acid. 182
Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease 179
Correlation of c-myc overexpression and amplification with progression of preneoplastic liver lesions to malignancy in the poorly susceptible Wistar rat strain 179
Jagged 1 is a major Notch ligand along cholangiocarcinoma development in mice and humans 177
Analysis of loss of heterozygosity in neoplastic nodules induced by diethylnitrosomine in the resistant BFF1 rat strain 176
c-myc amplification in pre-malignant and malignant lesions induced in rat liver by the resistant hepatocyte model 175
Chemopreventive N-(4-hydroxyphenyl)retinamide (fenretinide) targets deregulated NF-kappa B and Mat1A genes in the early stages of rat liver carcinogenesis 174
Chemoprevention of hepatocarcinogenesis: S.adenosyl-L-methionine 170
An infernal cross-talk between oncogenic β-catenin and c-Met in hepatocellular carcinoma: Evidence from mouse modeling 169
INHIBITION OF 3-HYDROXY-3-METHYLGLUTARY-COA REDUCTASE ACTIVITY AND GENE EXPRESSION BY DEHYDROEPIANDROSTERONE IN PRENEOPLASTIC LIVER NODULES 168
Benzo(a)pyrene metabolism by lymphocytes from normal individuals and individuals carrying the Mediterranean variant of glucose-6-phosphate dehydrogenase. 163
Amplification of c-myc oncogene in preneoplastic e neoplastic lesions induced in rat liver by the resistant hepatocyte protocol 160
Activation of v-Myb avian myeloblastosis viral oncogene homolog-like2 (MYBL2)-LIN9 complex contributes to human hepatocarcinogenesis and identifies a subset of hepatocellular carcinoma with mutant p53 157
Experimental models to define the genetic predisposition to liver cancer 157
Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis 156
Dependence of benzo(a)pyrene metabolism on NADPH pool in normal and glucose-6-phosphate dehydrogenase deficient human fibroblasts. 155
Comparative effects of L-methionine, S-adenosyl-L-methionine and 5'-methylthioadenosine on the growth of preneoplastic lesions and DNA methylation in rat liver during the early stages of hepatocarcinogenesis 152
Chemopreventive N-(4-hidroxyphenyl)retinamide targets NF-kB and Mat1A genes in early stages of rat liver carcinogenesis. 151
MicroRNA-203 impacts on the growth, aggressiveness and prognosis of hepatocellular carcinoma by targeting MAT2A and MAT2B genes 151
Role of HSP90,CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer 150
Deregulation of methionine metabolism as determinant of progression and prognosis of hepatocellular carcinoma 150
Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells 147
Dual-Specific Phosphatase 1 Ubiquitination in Extracellular Signal-Regulated Kinase-Mediated control of Grawth in Human Hepatocellular Carcinoma 145
Alterations of ornithine decarboxylase gene during the progression of rat liver carcinogenesis. 145
Inhibition of promotion and persistent nodule growth by S-adenosyl-L-methionine in rat liver carcinogenesis: role of remodeling and apoptosis 143
Effect of S-adenosyl-L-methionine on the development of preneoplastic foci and the activity of some carbohydrate metabolizing enzymes in the liver, during experimental hepatocarcinogenesis. 143
SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis 141
Combined CDK4/6 and pan-mTOR inhibition is synergistic against intrahepatic cholangiocarcinoma 140
New insights on the role of epigenetic alterations in hepatocellular carcinoma 139
Correlation between S-adenosyl-L-methionine content and production of c-myc, c-Ha-ras, and c-Ki-ras mRNA transcripts in the early stages of rat liver carcinogenesis. 138
Implication of Bcl 2 family genes in basal and D amphetamine induced apoptosis in preneoplastic and neoplastic rat liver lesions 138
Inhibition by dehydroepiandrosterone of growth and progression of persistent liver nodules in experimental rat liver carcinogenesis 137
Identification and chromosome mapping of loci predisposing to colorectal cancer that control Wnt/b-catenin pathway and progression of early lesions in the rat 136
Role of transcriptional and postttranscriptional regulation of methionine adenosyltransferases in liver cancer progression. 136
Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans 136
Chromosome mapping of multiple loci affecting the genetic predisposition to rat liver carcinogenesis 134
Laboratory test alterations in patients with COVID-19 and non COVID-19 interstitial pneumonia: a preliminary report 132
Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines in vitro and AKT-driven hepatocarcinogenesis in mice 131
Alterations of methionine metabolism as potential targets for the prevention and therapy of hepatocellular carcinoma 131
Oncogene-dependent addiction to carbohydrate-responsive element binding protein in hepatocellular carcinoma 130
Blood cell count indexes of systemic inflammation in carotid artery disease: current evidence and future perspectives 130
ROLE OF YAP SIGNALLING DEREGULATION IN THE GENETIC SUSCEPTIBILITY TO HEPATOCARCINOGENESIS, AND STEMNESS AND AGGRESSIVITY OF LIVER CANCER 129
Deregulation of DNA-dependent protein kinase catalytic subunit contributes to human hepatocarcinogenesis development and has a putative prognostic value 128
The degradation of cell cycle regulators by SKP2/CKS1 ubiquitin ligase is genetically controlled in rodent liver cancer and contributes to determine the susceptibility to the disease. 127
Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice 126
Stearoyl-CoA desaturase 1 (Scd1) gene overexpression is associated with genetic predisposition to hepatocarcinogenesis in mice and rats 126
S-adenosyl methionine regulates ubiquitin-conjugating enzyme 9 protein expression and sumoylation in murine liver and human cancers 126
S-Adenosylmethionine Regulates Apurinic/Apyrimidinic Endonuclease 1 Stability: Implication in Hepatocarcinogenesis 125
Differential effects of dehydroepiandrosterone and deoxyribonucleosides on DNA synthesis and de novo cholesterogenesis in hepatocarcinogenesis in rats. 125
Protooncogene methylation and expression in regenerating liver and preneoplastic liver nodules induced in the rat by diethylnitrosamine: effect of variations of S-adenosylmethionine:S-adenosylhomocysteine ratio. 124
THE BN RAT STRAIN CARRIES DOMINANT HEPATOCARCINOGEN RESISTANCE LOCI 124
Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC 123
Long-term dehydroepiandrosterone and 16alfa-fluoro-5-androsten-17-one administration enhances DNA synthesis and induces expression of c-fos and c-Ha-ras in a selected population of preneoplastic lesions in liver of diethylnitrosamine-initiated rats 120
Identification of genetic loci controlling hepatocarcinogenesis on rat chromosomes 7 and 10 119
Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease 119
SNAI1 promotes the cholangiocellular phenotype, but not epithelial-mesenchymal transition, in a murine hepatocellular carcinoma model 119
Inhibition by dehydroepiandrosterone of liver preneoplastic foci formation in rats after initiation-selection in experimental carcinogenesis. 119
DNA-PKcs: A promising therapeutic target in human hepatocellular carcinoma? 118
Persistent chemopreventive effect of S-adenosyl-L-methionine on the development of liver putative preneoplastic lesions induced by thiobenzamide in diethylnitrosamine-initiated rats 117
The mTORC2-Akt1 Cascade Is Crucial for c-Myc to Promote Hepatocarcinogenesis in Mice and Humans 117
Genetic Control of Resistance to Hepatocarcinogenesis by the Mouse Hpcr3 Locus 116
Control of glucose-6-phosphate dehydrogenase deficiency on the formation of mutagenic and carcinogenic metabolites derived from benzo(a)pyrene. 116
Phenotypic reversion of rat neoplastic liver nodules is under genetic control 115
Modulatory effect of glucose-6-phosphate dehydrogenase deficiency on benzo(a)pyrene toxicity and transforming activity for in vitro-cultured human skin fibroblasts. 114
Regulation of Amphiregulin Gene Expression by β-Catenin Signaling in Human Hepatocellular Carcinoma Cells: A Novel Crosstalk between FGF19 and the EGFR System 113
Polygenic control of hepatocarcinogenesis in Copenhagen x F344 rats 112
S-adenosylmethionine regulates dual-specificity mitogen-activated protein kinase phosphatase expression in mouse and human hepatocytes. 109
GENETIC AND EPIGENETIC CONTROL OF MOLECULAR ALTERATIONS IN HEPATOCELLULAR CARCINOMA 108
Multifocal hepatocellular carcinoma: intrahepatic metastasis or multicentric carcinogenesis? 107
Mybl2 expression is under genetic control and contributes to determine a hepatocellular carcinoma susceptible phenotype 107
Epigenetics of liver cancer progression: Role of transcriptional and post-transcriptional regulation of methionine adenosyltransferases in liver cancer progression. 106
The warburg effect 97 years after its discovery 106
Sulfatase 1: A new Jekyll and Hyde in hepatocellular carcinoma? 106
The post-transcriptional dysregulation of methionine adenosyl-transferases is crucial for the progression of rat and human liver cancer. 47° Annual Meeting of the European Association for Study of the Liver (EASL) Aprile 18-22, 2012 105
Inhibition of 3-hydroxy-3- methylglutaryl-CoA reductase activity and gene expression by dehydroepiandrosterone in preneolastic liver nodules 103
Reversal by ribo- and deoxyribonucleosides of dehydroepiandrosterone-induced inhibition of enzyme altered foci in the liver of rats subjected to the initiation--selection process of experimental carcinogenesis. 103
New putative prognostic markers and therapeutic targets for the molecular approach to treatment of hepatocellular carcinoma 103
Decreased stimulation by 12-O-tetradecanoylphorbol-13-acetate of superoxide radical production by polymorphonuclear leukocytes carrying the Mediterranean variant of glucose-6-phosphate dehydrogenase. 102
Effect of the variations of S-adenosyl-L-methionine liver content on fat accumulation and ethanol metabolism in ethanol-intoxicated rats 101
the role of S-adenosylmethionine in the regulation of glutathione pool and acetaldehyde production in acute ethanolintoxication 101
Variations of ornithine decarboxylase activity and S-adenosyl-L-methionine and 5'-methylthioadenosine contents during the development of diethylnitrosamine-induced liver hyperplastic nodules and hepatocellular carcinoma. 100
Ruolo di HSP90, CDC37 e CRM1 come modulatori dell’attività di p16 INK4A nella cancerogenesi epatica di ratto e nel carcinoma epatocellulare umano 98
Modulation of P16INK4 activity by HSP90, Cdc37 and CRM1 influences the progression of preneoplastico lesions in rats with different predisposition to liver cancer and the prognosis of human hepatocellular carcinoma 98
Reversal by 5-azacytidine of the S-adenosyl-L-methionine-induced inhibition of the development of putative preneoplastic foci in rat liver carcinogenesis 98
Connective tissue growth factor autocriny in human hepatocellular carcinoma: oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation. 97
Focal loss of long non-coding RNA-PRAL, as determinant of cell function and phenotype of hepatocellular carcinoma 97
Ras-driven proliferation and apoptosis signaling during rat liver carcinogenesis is under genetic control 94
Instabilità genomica nel carcinoma mammario 94
Role of Dehydroepiandrosterone in Experimental and Human Carcinogenesis 94
Role of phosphatidylethanolamine methylation in the synthesis of phosphatidylcholine by hepatocytes isolated from choline-deficient rats. 93
INTERACTION OF MAJOR GENES PREDISPOSING TO HEPATOCELLULAR CARCINOMA WITH GENES ENCODING SIGNAL TRANSDUCTION PATHWAYS INFLUENCES TUMOR PHENOTYPE AND PROGNOSIS 93
Mapping a sex-hormone sensitive gene determining female resistance to liver carcinogenesis in a congenic F344 BN-Hcs4 rat. 92
Totale 13.599
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Categoria #
all - tutte 66.239
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 66.239
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021363 0 0 0 0 0 0 0 0 0 180 148 35
2021/2022784 116 8 6 11 24 33 45 46 73 42 84 296
2022/20231.658 179 147 43 293 152 279 0 189 278 6 57 35
2023/2024390 89 27 13 16 54 15 0 14 0 3 53 106
2024/20254.323 30 39 223 120 204 149 323 745 1.433 686 258 113
2025/20266.022 314 1.541 951 767 554 380 790 187 261 277 0 0
Totale 16.826