IRIS
PASCALE, Rosa Maria
 Distribuzione geografica
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Continente #
NA - Nord America 3.459
EU - Europa 2.100
AS - Asia 1.744
SA - Sud America 18
OC - Oceania 16
Continente sconosciuto - Info sul continente non disponibili 13
Totale 7.350
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Nazione #
US - Stati Uniti d'America 3.422
CN - Cina 919
UA - Ucraina 810
SG - Singapore 429
DE - Germania 311
SE - Svezia 285
HK - Hong Kong 229
IT - Italia 228
FI - Finlandia 140
FR - Francia 113
GB - Regno Unito 85
TR - Turchia 83
CZ - Repubblica Ceca 49
BE - Belgio 39
CA - Canada 36
IR - Iran 18
IN - India 17
ID - Indonesia 16
KR - Corea 16
BR - Brasile 15
AU - Australia 14
EU - Europa 11
LT - Lituania 7
RO - Romania 6
AT - Austria 4
BD - Bangladesh 4
CH - Svizzera 3
EE - Estonia 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AE - Emirati Arabi Uniti 2
ES - Italia 2
IE - Irlanda 2
IQ - Iraq 2
JP - Giappone 2
NL - Olanda 2
NZ - Nuova Zelanda 2
PK - Pakistan 2
RU - Federazione Russa 2
SA - Arabia Saudita 2
AR - Argentina 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
CO - Colombia 1
DK - Danimarca 1
HU - Ungheria 1
IL - Israele 1
LU - Lussemburgo 1
LV - Lettonia 1
MM - Myanmar 1
MT - Malta 1
NP - Nepal 1
PA - Panama 1
PE - Perù 1
PL - Polonia 1
SI - Slovenia 1
Totale 7.350
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Città #
Chandler 955
Jacksonville 488
Singapore 347
Princeton 272
Hong Kong 228
Dearborn 200
Nanjing 198
Ann Arbor 165
Wilmington 137
Sassari 127
Nanchang 101
Shanghai 92
Boardman 87
Beijing 75
Izmir 74
Woodbridge 53
Changsha 52
Shenyang 51
Tianjin 48
Brno 45
Brussels 39
Hebei 38
Jinan 37
Jiaxing 32
Norwalk 30
Santa Clara 30
Falls Church 29
Ashburn 27
Helsinki 27
Toronto 26
Zhengzhou 26
Hangzhou 24
Ningbo 24
Guangzhou 22
Mountain View 22
Munich 20
Andover 19
Augusta 17
Kunming 17
San Mateo 17
Leawood 16
Dallas 15
Seoul 15
Ardabil 14
New York 13
Taizhou 13
Monmouth Junction 12
London 11
San Francisco 11
Los Angeles 10
Frankfurt am Main 9
Lanzhou 9
Changchun 8
Melbourne 8
Cagliari 7
Hefei 7
Tappahannock 7
Ottawa 6
Haikou 5
Messina 5
Auburn Hills 4
Berlin 4
Olomouc 4
San Jose 4
Vienna 4
Canberra 3
Chicago 3
Edinburgh 3
Grézieu-la-varenne 3
Milan 3
Mumbai 3
Perugia 3
Romola 3
Tallinn 3
Torino 3
Washington 3
Alghero 2
Almè 2
Beinasco 2
Cedar Knolls 2
Città Di Castello 2
Cortoghiana 2
Dublin 2
Falkenstein 2
Fuzhou 2
Houston 2
Orange 2
Pompei 2
Redwood City 2
Rome 2
Sogliano al Rubicone 2
Stockholm 2
São Paulo 2
Wuppertal 2
Xi'an 2
Adliswil 1
Auckland 1
Baghdad 1
Bahía Blanca 1
Barueri 1
Totale 4.615
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Nome #
INHIBITION OF 3-HYDROXY-3-METHYLGLUTARY-COA REDUCTASE ACTIVITY AND GENE EXPRESSION BY DEHYDROEPIANDROSTERONE IN PRENEOPLASTIC LIVER NODULES 98
1-5-formyltetrahydrofolate and 1-5-methyltetrahydrofolate rescue in L-1210 leukemia treated with high methotrexate doses 93
Correlation of c-myc overexpression and amplification with progression of preneoplastic liver lesions to malignancy in the poorly susceptible Wistar rat strain 92
Chemopreventive N-(4-hydroxyphenyl)retinamide (fenretinide) targets deregulated NF-kappa B and Mat1A genes in the early stages of rat liver carcinogenesis 87
New insights on the role of epigenetic alterations in hepatocellular carcinoma 85
Jagged 1 is a major Notch ligand along cholangiocarcinoma development in mice and humans 82
Alterations of methionine metabolism in hepatocarcinogenesis: the emergent role of glycine N-methyltransferase in liver injury 82
Role of HSP90,CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer 81
Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells 80
Polygenic control of hepatocarcinogenesis in Copenhagen x F344 rats 78
Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans 74
Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis 73
Chemoprevention of hepatocarcinogenesis: S.adenosyl-L-methionine 73
Analysis of loss of heterozygosity in neoplastic nodules induced by diethylnitrosomine in the resistant BFF1 rat strain 71
ROLE OF YAP SIGNALLING DEREGULATION IN THE GENETIC SUSCEPTIBILITY TO HEPATOCARCINOGENESIS, AND STEMNESS AND AGGRESSIVITY OF LIVER CANCER 70
Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease 69
Decreased stimulation by 12-O-tetradecanoylphorbol-13-acetate of superoxide radical production by polymorphonuclear leukocytes carrying the Mediterranean variant of glucose-6-phosphate dehydrogenase. 68
Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans 68
S-adenosyl methionine regulates ubiquitin-conjugating enzyme 9 protein expression and sumoylation in murine liver and human cancers 68
Experimental models to define the genetic predisposition to liver cancer 68
Deregulation of methionine metabolism as determinant of progression and prognosis of hepatocellular carcinoma 67
Chemoprevention of rat liver carcinogenesis by S-adenosyl-L-methionine: a long-term study. 66
Dependence of benzo(a)pyrene metabolism on NADPH pool in normal and glucose-6-phosphate dehydrogenase deficient human fibroblasts. 66
Implication of Bcl 2 family genes in basal and D amphetamine induced apoptosis in preneoplastic and neoplastic rat liver lesions 65
The mTORC2-Akt1 Cascade Is Crucial for c-Myc to Promote Hepatocarcinogenesis in Mice and Humans 65
Control of glucose-6-phosphate dehydrogenase deficiency on the formation of mutagenic and carcinogenic metabolites derived from benzo(a)pyrene. 65
MicroRNA-203 impacts on the growth, aggressiveness and prognosis of hepatocellular carcinoma by targeting MAT2A and MAT2B genes 65
A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis 64
Effect of S-adenosyl-L-methionine on the development of preneoplastic foci and the activity of some carbohydrate metabolizing enzymes in the liver, during experimental hepatocarcinogenesis. 64
Inhibition of promotion and persistent nodule growth by S-adenosyl-L-methionine in rat liver carcinogenesis: role of remodeling and apoptosis 63
Modulatory effect of glucose-6-phosphate dehydrogenase deficiency on benzo(a)pyrene toxicity and transforming activity for in vitro-cultured human skin fibroblasts. 63
5' Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon tetrachloride intoxication 63
Identification and chromosome mapping of loci predisposing to colorectal cancer that control Wnt/b-catenin pathway and progression of early lesions in the rat 62
Protooncogene methylation and expression in regenerating liver and preneoplastic liver nodules induced in the rat by diethylnitrosamine: effect of variations of S-adenosylmethionine:S-adenosylhomocysteine ratio. 61
Phenotypic reversion of rat neoplastic liver nodules is under genetic control 61
THE BN RAT STRAIN CARRIES DOMINANT HEPATOCARCINOGEN RESISTANCE LOCI 61
Chromosome mapping of multiple loci affecting the genetic predisposition to rat liver carcinogenesis 61
Reversal by ribo- and deoxyribonucleosides of dehydroepiandrosterone-induced inhibition of enzyme altered foci in the liver of rats subjected to the initiation--selection process of experimental carcinogenesis. 61
Regulation of Amphiregulin Gene Expression by β-Catenin Signaling in Human Hepatocellular Carcinoma Cells: A Novel Crosstalk between FGF19 and the EGFR System 61
Cell cycle deregulation in liver lesions of rats with and without genetic predisposition to hepatocarcinogenesis 61
Dual-Specific Phosphatase 1 Ubiquitination in Extracellular Signal-Regulated Kinase-Mediated control of Grawth in Human Hepatocellular Carcinoma 61
Role of phosphatidylethanolamine methylation in the synthesis of phosphatidylcholine by hepatocytes isolated from choline-deficient rats. 60
Identification of genetic loci controlling hepatocarcinogenesis on rat chromosomes 7 and 10 60
Inhibition by dehydroepiandrosterone of growth and progression of persistent liver nodules in experimental rat liver carcinogenesis 60
Prognostic markers and putative therapeutic targets for hepatocellular carcinoma. 60
Role of transcriptional and postttranscriptional regulation of methionine adenosyltransferases in liver cancer progression. 60
c-myc amplification in pre-malignant and malignant lesions induced in rat liver by the resistant hepatocyte model 60
. Chemoprevention by S-adenosyl-L-methionine of rat liver carcinogenesis initiated by 1,2-dimethylhydrazine and promoted by orotic acid. 60
An infernal cross-talk between oncogenic β-catenin and c-Met in hepatocellular carcinoma: Evidence from mouse modeling 60
Comparative effects of L-methionine, S-adenosyl-L-methionine and 5'-methylthioadenosine on the growth of preneoplastic lesions and DNA methylation in rat liver during the early stages of hepatocarcinogenesis 59
SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis 59
Benzo(a)pyrene metabolism by lymphocytes from normal individuals and individuals carrying the Mediterranean variant of glucose-6-phosphate dehydrogenase. 59
Amplification of c-myc oncogene in preneoplastic e neoplastic lesions induced in rat liver by the resistant hepatocyte protocol 58
Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease 58
Persistent chemopreventive effect of S-adenosyl-L-methionine on the development of liver putative preneoplastic lesions induced by thiobenzamide in diethylnitrosamine-initiated rats 58
Combined CDK4/6 and pan-mTOR inhibition is synergistic against intrahepatic cholangiocarcinoma 58
Alterations of ornithine decarboxylase gene during the progression of rat liver carcinogenesis. 58
INTERACTION OF MAJOR GENES PREDISPOSING TO HEPATOCELLULAR CARCINOMA WITH GENES ENCODING SIGNAL TRANSDUCTION PATHWAYS INFLUENCES TUMOR PHENOTYPE AND PROGNOSIS 58
S-Adenosylmethionine Regulates Apurinic/Apyrimidinic Endonuclease 1 Stability: Implication in Hepatocarcinogenesis 57
Chemopreventive N-(4-hidroxyphenyl)retinamide targets NF-kB and Mat1A genes in early stages of rat liver carcinogenesis. 57
Correlation between S-adenosyl-L-methionine content and production of c-myc, c-Ha-ras, and c-Ki-ras mRNA transcripts in the early stages of rat liver carcinogenesis. 57
Differential effects of dehydroepiandrosterone and deoxyribonucleosides on DNA synthesis and de novo cholesterogenesis in hepatocarcinogenesis in rats. 57
GENETIC AND EPIGENETIC CONTROL OF MOLECULAR ALTERATIONS IN HEPATOCELLULAR CARCINOMA 56
Transferrin and transferrin receptor gene expression in benign and malignant rat liver lesions. 56
Role of Dehydroepiandrosterone in Experimental and Human Carcinogenesis 56
Construction of a phylogenetic tree for inbred strains of rat by arbitrarily primed polymerase chain reaction (AP-PCR). 55
Variations of ornithine decarboxylase activity and S-adenosyl-L-methionine and 5'-methylthioadenosine contents during the development of diethylnitrosamine-induced liver hyperplastic nodules and hepatocellular carcinoma. 55
New putative prognostic markers and therapeutic targets for the molecular approach to treatment of hepatocellular carcinoma 55
An expression signature of phenotipic resistance to hepatocellular carcinoma identified by cross-species gene expression analysis 55
Inhibition by dehydroepiandrosterone of liver preneoplastic foci formation in rats after initiation-selection in experimental carcinogenesis. 55
Long-term dehydroepiandrosterone and 16alfa-fluoro-5-androsten-17-one administration enhances DNA synthesis and induces expression of c-fos and c-Ha-ras in a selected population of preneoplastic lesions in liver of diethylnitrosamine-initiated rats 55
Expression of N-acetylglucosaminyltransferase III in hepatic nodules generated by different models of rat liver carcinogenesis. 54
Deregulation of DNA-dependent protein kinase catalytic subunit contributes to human hepatocarcinogenesis development and has a putative prognostic value 53
Genetic Control of Resistance to Hepatocarcinogenesis by the Mouse Hpcr3 Locus 53
Effect of the variations of S-adenosyl-L-methionine liver content on fat accumulation and ethanol metabolism in ethanol-intoxicated rats 53
Epigenetics of liver cancer progression: Role of transcriptional and post-transcriptional regulation of methionine adenosyltransferases in liver cancer progression. 53
Mapping a sex-hormone sensitive gene determining female resistance to liver carcinogenesis in a congenic F344 BN-Hcs4 rat. 53
The post-transcriptional dysregulation of methionine adenosyl-transferases is crucial for the progression of rat and human liver cancer. 47° Annual Meeting of the European Association for Study of the Liver (EASL) Aprile 18-22, 2012 52
Ruolo di HSP90, CDC37 e CRM1 come modulatori dell’attività di p16 INK4A nella cancerogenesi epatica di ratto e nel carcinoma epatocellulare umano 52
Multifocal hepatocellular carcinoma: intrahepatic metastasis or multicentric carcinogenesis? 52
Ras-driven proliferation and apoptosis signaling during rat liver carcinogenesis is under genetic control 51
the role of S-adenosylmethionine in the regulation of glutathione pool and acetaldehyde production in acute ethanolintoxication 51
Early stimulation of polyamine biosynthesis during promotion by phenobarbital of diethylnitrosamine-induced rat liver carcinogenesis. The effects of variations of the S-adenosyl-L-methionine cellular pooL 51
Sulfatase 1: A new Jekyll and Hyde in hepatocellular carcinoma? 51
Genetic alterations in liver carcinogenesis: implication for new preventive therapeutic strategies 50
Deregulation of signalling pathways in prognostic subtypes of hepatocellular carcinoma: Novel insights from interspecies comparison 50
Reversal by 5-azacytidine of the S-adenosyl-L-methionine-induced inhibition of the development of putative preneoplastic foci in rat liver carcinogenesis 50
Inhibition by ethanol of rat liver plasma membrane (Na+,K+)ATPase: protective effect of S-adenosyl-L-methionine, L-methionine, and N-acetylcysteine. 50
Stearoyl-CoA desaturase 1 (Scd1) gene overexpression is associated with genetic predisposition to hepatocarcinogenesis in mice and rats 50
DNA-PKcs: A promising therapeutic target in human hepatocellular carcinoma? 49
Laboratory test alterations in patients with COVID-19 and non COVID-19 interstitial pneumonia: a preliminary report 49
SNAI1 promotes the cholangiocellular phenotype, but not epithelial-mesenchymal transition, in a murine hepatocellular carcinoma model 49
Focal loss of long non-coding RNA-PRAL, as determinant of cell function and phenotype of hepatocellular carcinoma 49
The role of phosphatidylethanolamine methylation in the synthesis of phosphatidylcholinein acute ethanol intoxication. 49
Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice 48
Modulatory mechanisms of chemical carcinogenesis: the role of the NADPH pool in the benzo(a)pyrene activation. 47
The degradation of cell cycle regulators by SKP2/CKS1 ubiquitin ligase is genetically controlled in rodent liver cancer and contributes to determine the susceptibility to the disease. 47
Connective tissue growth factor autocriny in human hepatocellular carcinoma: oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation. 47
TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma 47
Mybl2 expression is under genetic control and contributes to determine a hepatocellular carcinoma susceptible phenotype 47
Totale 6.074
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Categoria #
all - tutte 41.287
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.287
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020689 0 0 0 0 0 0 303 33 146 55 142 10
2020/20211.249 133 6 188 13 135 72 143 8 188 180 148 35
2021/2022784 116 8 6 11 24 33 45 46 73 42 84 296
2022/20231.658 179 147 43 293 152 279 0 189 278 6 57 35
2023/2024390 89 27 13 16 54 15 0 14 0 3 53 106
2024/20251.004 30 39 223 120 204 149 239 0 0 0 0 0
Totale 7.485