lncRNA-PRAL down-regulation may be responsible for p53 inactivation in p53-wild type HCC. Indeed apoptosis is absent in p53-deficient (Hep3B) or p53-mutant (Huh7) cells cultured in presence of lncRNA-PRAL.
Focal loss of long non-coding RNA-PRAL, as determinant of cell function and phenotype of hepatocellular carcinoma / Feo, Francesco; Simile, Maria Maddalena; Pascale, Rosa Maria. - In: ANNALS OF TRANSLATIONAL MEDICINE. - ISSN 2305-5839. - 4:9(2016), p. 183. [10.21037/atm.2016.03.47]
Focal loss of long non-coding RNA-PRAL, as determinant of cell function and phenotype of hepatocellular carcinoma
FEO, Francesco;SIMILE, Maria Maddalena;PASCALE, Rosa Maria
2016-01-01
Abstract
lncRNA-PRAL down-regulation may be responsible for p53 inactivation in p53-wild type HCC. Indeed apoptosis is absent in p53-deficient (Hep3B) or p53-mutant (Huh7) cells cultured in presence of lncRNA-PRAL.File in questo prodotto:
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