SIMILE, Maria Maddalena
SIMILE, Maria Maddalena
MEDICINA, CHIRURGIA E FARMACIA
. Chemoprevention by S-adenosyl-L-methionine of rat liver carcinogenesis initiated by 1,2-dimethylhydrazine and promoted by orotic acid.
1995-01-01 Pascale, Rosa Maria; Simile, Maria Maddalena; DE MIGLIO, Maria Rosaria; Nufris, A; Daino, L; Seddaiu, Maria Antonietta; Rao, Pm; Rajalakshmi, S; Sarma, Ds; Feo, F.
1-5-formyltetrahydrofolate and 1-5-methyltetrahydrofolate rescue in L-1210 leukemia treated with high methotrexate doses
1993-01-01 Simile, Maria Maddalena; DE MIGLIO, Maria Rosaria; Nufris, A; Pascale, Rosa Maria; Muroni, Maria Rosaria; Feo, F.
5' Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon tetrachloride intoxication
2001-01-01 Simile, Maria Maddalena; Banni, S; Angioni, E; Carta, G; DE MIGLIO, Maria Rosaria; Muroni, Maria Rosaria; Calvisi, Diego Francesco; Carru, A; Pascale, Rosa Maria; Feo, F.
Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease
2008-01-01 Calvisi, Diego Francesco; Pinna, F.; Ladu, S.; Pellegrino, R.; Muroni, Maria Rosaria; Simile, Maria Maddalena; Frau, M.; Tomasi, M. L.; DE MIGLIO, Maria Rosaria; Seddaiu, Maria Antonietta; Daino, L.; Sanna, V.; Feo, F.; Pascale, Rosa Maria
Activation of v-Myb avian myeloblastosis viral oncogene homolog-like2 (MYBL2)-LIN9 complex contributes to human hepatocarcinogenesis and identifies a subset of hepatocellular carcinoma with mutant p53
2011-01-01 Calvisi, Diego Francesco; Simile, Maria Maddalena; Ladu, S; Frau, M; Evert, M; Tomasi, Ml; Demartis, Maria Ilaria; Daino, L; Seddaiu, Maria Antonietta; Brozzetti, S; Feo, F; Pascale, Rosa Maria
Alterations of methionine metabolism as potential targets for the prevention and therapy of hepatocellular carcinoma
2019-01-01 Pascale, R. M.; Peitta, G.; Simile, M. M.; Feo, F.
Alterations of methionine metabolism in hepatocarcinogenesis: the emergent role of glycine N-methyltransferase in liver injury
2018-01-01 Simile, Maria M.; Latte, Gavinella; Feo, Claudio F.; Feo, Francesco; Calvisi, Diego F.; Pascale, Rosa M.
Alterations of ornithine decarboxylase gene during the progression of rat liver carcinogenesis.
1993-01-01 Pascale, Rosa Maria; Simile, Maria Maddalena; Gaspa, Leonardo; Daino, L; Seddaiu, Maria Antonietta; Pinna, G; Carta, M; Zolo, P; Feo, F.
Altered methionine metabolism and global DNA methylation in liver cancer: Relationship with genomic instability and prognosis
2007-01-01 Calvisi, Diego Francesco; Simile, Maria Maddalena; Ladu, S; Pellegrino, R; DE MURTAS, V; Pinna, F; Tomasi, Ml; Frau, M; Virdis, P; DE MIGLIO, Maria Rosaria; Muroni, Maria Rosaria; Pascale, Rosa Maria; Feo, F.
Amplification of c-myc oncogene in preneoplastic e neoplastic lesions induced in rat liver by the resistant hepatocyte protocol
1996-01-01 DE MIGLIO, Maria Rosaria; Muroni, Maria Rosaria; Nufris, A; Simile, Maria Maddalena; Gaspa, L; Deiana, L; Pascale, Rosa Maria; Feo, F.
An expression signature of phenotipic resistance to hepatocellular carcinoma identified by cross-species gene expression analysis
2012-01-01 Frau, Maddalena; Simile, Maria Maddalena; Tomasi, Maria L.; Demartis, Maria Ilaria; Daino, Lucia; Seddaiu, Maria Antonietta; Brozzetti, Stefania; Feo, Claudio; Massarelli, Giovannino; Solinas, Maria Giuliana; Feo, Francesco; Lee, Ju Seog; Pascale, Rosa Maria
c-myc amplification in pre-malignant and malignant lesions induced in rat liver by the resistant hepatocyte model
1996-01-01 Pascale, R. M.; DE MIGLIO, Maria Rosaria; Muroni, M. R.; Nufris, A.; Simile, M. M.; Daino, L.; Seddaiu, M. A.; Gaspa, L.; Deiana, L.; And, Feo
Cell cycle deregulation in liver lesions of rats with and without genetic predisposition to hepatocarcinogenesis
2002-01-01 Pascale, Rosa Maria; Simile, Maria Maddalena; DE MIGLIO, Maria Rosaria; Muroni, Maria Rosaria; Calvisi, Diego Francesco; Asara, G; Casabona, D; Frau, M; Seddaiu, Maria Antonietta; Feo, F.
Chemoprevention of hepatocarcinogenesis: S.adenosyl-L-methionine
2002-01-01 Pascale, Rosa Maria; Simile, Maria Maddalena; DE MIGLIO, Maria Rosaria; Feo, F.
Chemoprevention of rat liver carcinogenesis by S-adenosyl-L-methionine: a long-term study.
1992-01-01 Pascale, Rosa Maria; Marras, V; Simile, Maria Maddalena; Daino, L; Pinna, G; Bennati, S; Carta, M; Seddaiu, Maria Antonietta; Massarelli, Giovannino; Feo, F.
Chemopreventive N-(4-hidroxyphenyl)retinamide targets NF-kB and Mat1A genes in early stages of rat liver carcinogenesis.
2004-01-01 Simile, Maria Maddalena; Pagnan, G; DE MIGLIO, Maria Rosaria; Muroni, Maria Rosaria; Asara, G; Frau, M; Seddaiu, Ma; Feo, F; Ponzoni, M; Pascale, Rosa Maria
Chemopreventive N-(4-hydroxyphenyl)retinamide (fenretinide) targets deregulated NF-kappa B and Mat1A genes in the early stages of rat liver carcinogenesis
2005-01-01 Simile, Maria Maddalena; Pagnan, G.; Pastorino, F.; Brignole, C.; DE MIGLIO, Maria Rosaria; Muroni, Maria Rosaria; Asara, G.; Frau, M.; Seddaiu, Maria Antonietta; Calvisi, Diego Francesco; Feo, F.; Ponzoni, M.; Pascale, Rosa Maria
Chromosome mapping of multiple loci affecting the genetic predisposition to rat liver carcinogenesis
2002-01-01 DE MIGLIO, Maria Rosaria; Pascale, Rosa Maria; Simile, Maria Maddalena; Muroni, Maria Rosaria; Calvisi, Diego Francesco; Virdis, P; Bosinco, Gm; Frau, M; Seddaiu, Maria Antonietta; Ladu, S; Feo, F.
Comparative effects of L-methionine, S-adenosyl-L-methionine and 5'-methylthioadenosine on the growth of preneoplastic lesions and DNA methylation in rat liver during the early stages of hepatocarcinogenesis
1991-01-01 Pascale, Rosa Maria; Simile, Maria Maddalena; Satta, G; Seddaiu, Maria Antonietta; Daino, L; Pinna, G; Vinci, Ma; Gaspa, Leonardo; Feo, F.
Correlation between S-adenosyl-L-methionine content and production of c-myc, c-Ha-ras, and c-Ki-ras mRNA transcripts in the early stages of rat liver carcinogenesis.
1994-01-01 Simile, Maria Maddalena; Pascale, Rosa Maria; DE MIGLIO, Maria Rosaria; Nufris, A; Daino, L; Seddaiu, Maria Antonietta; Gaspa, Leonardo; Feo, F.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| . Chemoprevention by S-adenosyl-L-methionine of rat liver carcinogenesis initiated by 1,2-dimethylhydrazine and promoted by orotic acid. | 1-gen-1995 | Pascale, Rosa Maria; Simile, Maria Maddalena; DE MIGLIO, Maria Rosaria; Nufris, A; Daino, L; Seddaiu, Maria Antonietta; Rao, Pm; Rajalakshmi, S; Sarma, Ds; Feo, F. | |
| 1-5-formyltetrahydrofolate and 1-5-methyltetrahydrofolate rescue in L-1210 leukemia treated with high methotrexate doses | 1-gen-1993 | Simile, Maria Maddalena; DE MIGLIO, Maria Rosaria; Nufris, A; Pascale, Rosa Maria; Muroni, Maria Rosaria; Feo, F. | |
| 5' Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon tetrachloride intoxication | 1-gen-2001 | Simile, Maria Maddalena; Banni, S; Angioni, E; Carta, G; DE MIGLIO, Maria Rosaria; Muroni, Maria Rosaria; Calvisi, Diego Francesco; Carru, A; Pascale, Rosa Maria; Feo, F. | |
| Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease | 1-gen-2008 | Calvisi, Diego Francesco; Pinna, F.; Ladu, S.; Pellegrino, R.; Muroni, Maria Rosaria; Simile, Maria Maddalena; Frau, M.; Tomasi, M. L.; DE MIGLIO, Maria Rosaria; Seddaiu, Maria Antonietta; Daino, L.; Sanna, V.; Feo, F.; Pascale, Rosa Maria | |
| Activation of v-Myb avian myeloblastosis viral oncogene homolog-like2 (MYBL2)-LIN9 complex contributes to human hepatocarcinogenesis and identifies a subset of hepatocellular carcinoma with mutant p53 | 1-gen-2011 | Calvisi, Diego Francesco; Simile, Maria Maddalena; Ladu, S; Frau, M; Evert, M; Tomasi, Ml; Demartis, Maria Ilaria; Daino, L; Seddaiu, Maria Antonietta; Brozzetti, S; Feo, F; Pascale, Rosa Maria | |
| Alterations of methionine metabolism as potential targets for the prevention and therapy of hepatocellular carcinoma | 1-gen-2019 | Pascale, R. M.; Peitta, G.; Simile, M. M.; Feo, F. | |
| Alterations of methionine metabolism in hepatocarcinogenesis: the emergent role of glycine N-methyltransferase in liver injury | 1-gen-2018 | Simile, Maria M.; Latte, Gavinella; Feo, Claudio F.; Feo, Francesco; Calvisi, Diego F.; Pascale, Rosa M. | |
| Alterations of ornithine decarboxylase gene during the progression of rat liver carcinogenesis. | 1-gen-1993 | Pascale, Rosa Maria; Simile, Maria Maddalena; Gaspa, Leonardo; Daino, L; Seddaiu, Maria Antonietta; Pinna, G; Carta, M; Zolo, P; Feo, F. | |
| Altered methionine metabolism and global DNA methylation in liver cancer: Relationship with genomic instability and prognosis | 1-gen-2007 | Calvisi, Diego Francesco; Simile, Maria Maddalena; Ladu, S; Pellegrino, R; DE MURTAS, V; Pinna, F; Tomasi, Ml; Frau, M; Virdis, P; DE MIGLIO, Maria Rosaria; Muroni, Maria Rosaria; Pascale, Rosa Maria; Feo, F. | |
| Amplification of c-myc oncogene in preneoplastic e neoplastic lesions induced in rat liver by the resistant hepatocyte protocol | 1-gen-1996 | DE MIGLIO, Maria Rosaria; Muroni, Maria Rosaria; Nufris, A; Simile, Maria Maddalena; Gaspa, L; Deiana, L; Pascale, Rosa Maria; Feo, F. | |
| An expression signature of phenotipic resistance to hepatocellular carcinoma identified by cross-species gene expression analysis | 1-gen-2012 | Frau, Maddalena; Simile, Maria Maddalena; Tomasi, Maria L.; Demartis, Maria Ilaria; Daino, Lucia; Seddaiu, Maria Antonietta; Brozzetti, Stefania; Feo, Claudio; Massarelli, Giovannino; Solinas, Maria Giuliana; Feo, Francesco; Lee, Ju Seog; Pascale, Rosa Maria | |
| c-myc amplification in pre-malignant and malignant lesions induced in rat liver by the resistant hepatocyte model | 1-gen-1996 | Pascale, R. M.; DE MIGLIO, Maria Rosaria; Muroni, M. R.; Nufris, A.; Simile, M. M.; Daino, L.; Seddaiu, M. A.; Gaspa, L.; Deiana, L.; And, Feo | |
| Cell cycle deregulation in liver lesions of rats with and without genetic predisposition to hepatocarcinogenesis | 1-gen-2002 | Pascale, Rosa Maria; Simile, Maria Maddalena; DE MIGLIO, Maria Rosaria; Muroni, Maria Rosaria; Calvisi, Diego Francesco; Asara, G; Casabona, D; Frau, M; Seddaiu, Maria Antonietta; Feo, F. | |
| Chemoprevention of hepatocarcinogenesis: S.adenosyl-L-methionine | 1-gen-2002 | Pascale, Rosa Maria; Simile, Maria Maddalena; DE MIGLIO, Maria Rosaria; Feo, F. | |
| Chemoprevention of rat liver carcinogenesis by S-adenosyl-L-methionine: a long-term study. | 1-gen-1992 | Pascale, Rosa Maria; Marras, V; Simile, Maria Maddalena; Daino, L; Pinna, G; Bennati, S; Carta, M; Seddaiu, Maria Antonietta; Massarelli, Giovannino; Feo, F. | |
| Chemopreventive N-(4-hidroxyphenyl)retinamide targets NF-kB and Mat1A genes in early stages of rat liver carcinogenesis. | 1-gen-2004 | Simile, Maria Maddalena; Pagnan, G; DE MIGLIO, Maria Rosaria; Muroni, Maria Rosaria; Asara, G; Frau, M; Seddaiu, Ma; Feo, F; Ponzoni, M; Pascale, Rosa Maria | |
| Chemopreventive N-(4-hydroxyphenyl)retinamide (fenretinide) targets deregulated NF-kappa B and Mat1A genes in the early stages of rat liver carcinogenesis | 1-gen-2005 | Simile, Maria Maddalena; Pagnan, G.; Pastorino, F.; Brignole, C.; DE MIGLIO, Maria Rosaria; Muroni, Maria Rosaria; Asara, G.; Frau, M.; Seddaiu, Maria Antonietta; Calvisi, Diego Francesco; Feo, F.; Ponzoni, M.; Pascale, Rosa Maria | |
| Chromosome mapping of multiple loci affecting the genetic predisposition to rat liver carcinogenesis | 1-gen-2002 | DE MIGLIO, Maria Rosaria; Pascale, Rosa Maria; Simile, Maria Maddalena; Muroni, Maria Rosaria; Calvisi, Diego Francesco; Virdis, P; Bosinco, Gm; Frau, M; Seddaiu, Maria Antonietta; Ladu, S; Feo, F. | |
| Comparative effects of L-methionine, S-adenosyl-L-methionine and 5'-methylthioadenosine on the growth of preneoplastic lesions and DNA methylation in rat liver during the early stages of hepatocarcinogenesis | 1-gen-1991 | Pascale, Rosa Maria; Simile, Maria Maddalena; Satta, G; Seddaiu, Maria Antonietta; Daino, L; Pinna, G; Vinci, Ma; Gaspa, Leonardo; Feo, F. | |
| Correlation between S-adenosyl-L-methionine content and production of c-myc, c-Ha-ras, and c-Ki-ras mRNA transcripts in the early stages of rat liver carcinogenesis. | 1-gen-1994 | Simile, Maria Maddalena; Pascale, Rosa Maria; DE MIGLIO, Maria Rosaria; Nufris, A; Daino, L; Seddaiu, Maria Antonietta; Gaspa, Leonardo; Feo, F. |