IRIS
SESTITO, Simona
 Distribuzione geografica
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Continente #
NA - Nord America 2.282
AS - Asia 1.226
SA - Sud America 855
EU - Europa 449
AF - Africa 44
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 2
Totale 4.865
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Nazione #
US - Stati Uniti d'America 2.235
BR - Brasile 754
SG - Singapore 671
CN - Cina 190
HK - Hong Kong 126
DE - Germania 114
UA - Ucraina 114
IT - Italia 52
AR - Argentina 42
VN - Vietnam 35
GB - Regno Unito 32
TR - Turchia 29
IN - India 25
IQ - Iraq 23
FR - Francia 22
RU - Federazione Russa 21
CA - Canada 20
BD - Bangladesh 17
KR - Corea 17
BE - Belgio 15
MX - Messico 14
SE - Svezia 14
UZ - Uzbekistan 14
PL - Polonia 13
VE - Venezuela 13
PK - Pakistan 12
ZA - Sudafrica 12
EC - Ecuador 11
FI - Finlandia 11
JP - Giappone 11
ID - Indonesia 10
CO - Colombia 9
ES - Italia 8
EG - Egitto 7
NL - Olanda 7
PY - Paraguay 7
AE - Emirati Arabi Uniti 6
KE - Kenya 6
UY - Uruguay 6
DZ - Algeria 5
MA - Marocco 5
PE - Perù 5
TN - Tunisia 5
AT - Austria 4
CL - Cile 4
EU - Europa 4
IL - Israele 4
JO - Giordania 4
CZ - Repubblica Ceca 3
GE - Georgia 3
HN - Honduras 3
KG - Kirghizistan 3
NP - Nepal 3
RO - Romania 3
RS - Serbia 3
AU - Australia 2
BA - Bosnia-Erzegovina 2
BG - Bulgaria 2
BN - Brunei Darussalam 2
BO - Bolivia 2
BY - Bielorussia 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
GA - Gabon 2
IR - Iran 2
JM - Giamaica 2
KW - Kuwait 2
KZ - Kazakistan 2
LB - Libano 2
OM - Oman 2
PA - Panama 2
PS - Palestinian Territory 2
XK - ???statistics.table.value.countryCode.XK??? 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
AZ - Azerbaigian 1
BH - Bahrain 1
CI - Costa d'Avorio 1
CR - Costa Rica 1
GR - Grecia 1
GT - Guatemala 1
GY - Guiana 1
KH - Cambogia 1
LT - Lituania 1
MK - Macedonia 1
MM - Myanmar 1
MN - Mongolia 1
NG - Nigeria 1
NI - Nicaragua 1
NO - Norvegia 1
PR - Porto Rico 1
QA - Qatar 1
SA - Arabia Saudita 1
SR - Suriname 1
SY - Repubblica araba siriana 1
TJ - Tagikistan 1
Totale 4.865
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Città #
Dallas 700
Chandler 462
Singapore 425
Hong Kong 124
Ashburn 102
New York 96
Beijing 80
Princeton 80
São Paulo 54
Ann Arbor 48
Wilmington 41
Jacksonville 32
Shanghai 29
Belo Horizonte 26
The Dalles 26
Columbus 23
Los Angeles 23
Council Bluffs 20
Rio de Janeiro 20
Boardman 18
Seoul 17
Brasília 16
Falls Church 16
Santa Clara 16
Ho Chi Minh City 15
Mountain View 14
Tashkent 14
Baghdad 13
Brussels 13
San Francisco 13
Warsaw 13
Curitiba 12
Porto Alegre 12
Düsseldorf 11
Munich 11
Sassari 11
Tokyo 11
Ankara 10
Jakarta 10
West Jordan 10
Hanoi 9
Phoenix 9
Poplar 9
Recife 9
San Jose 9
Campinas 8
London 8
Norwalk 8
Brooklyn 7
Buenos Aires 7
Cagliari 7
Denver 7
Montreal 7
Orem 7
Presidente Prudente 7
Salvador 7
São Gonçalo 7
Alvorada 6
Boston 6
Buffalo 6
Cairo 6
Fortaleza 6
Franca 6
Helsinki 6
Indaiatuba 6
Istanbul 6
Mumbai 6
Toronto 6
Asunción 5
Atlanta 5
Chennai 5
Duque de Caxias 5
Frankfurt am Main 5
Guarulhos 5
Johannesburg 5
Medellín 5
Montevideo 5
Nairobi 5
Praia Grande 5
Ribeirão Preto 5
Romola 5
Santa Maria 5
São José do Rio Preto 5
Amman 4
Amsterdam 4
Balneário Camboriú 4
Bragança Paulista 4
Cabo Frio 4
Canoas 4
Cape Town 4
Caraguatatuba 4
Contagem 4
Dhaka 4
Erbil 4
Lahore 4
Lima 4
Manaus 4
Maringá 4
Moscow 4
Osasco 4
Totale 3.028
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Nome #
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs) 183
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) 178
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DI PDK1 177
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DUALI DI PDK1/AurA” 167
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA 164
H2S-BASED THERAPEUTIC AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES 158
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease? 149
Design, Synthesis, and Antiviral Activities of New Benzotriazole-Based Derivatives 145
Design, synthesis, and biological screening of a series of 4′-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) 143
A patent update on PDK1 inhibitors (2015-present) 142
Antibiotics and Carbohydrate-Containing Drugs Targeting Bacterial Cell Envelopes: An Overview 135
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 135
Inhibition of Enterovirus A71 by a Novel 2-Phenyl-Benzimidazole Derivative 133
ACE2 in the Era of SARS-CoV-2: Controversies and Novel Perspectives 121
Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics 119
Synthesis and pharmacological characterization of mitochondrial KATP channel openers with enhanced mitochondriotropic effects 119
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis 113
Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease 110
3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome? 109
Areca catechu—From farm to food and biomedical applications 108
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 105
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 104
Endogenous 3-iodothyronamine (T1Am) and synthetic thyronamine-like analog SG-2 act as novel pleiotropic neuroprotective agents through the modulation of SIRT6 96
Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D‐Like CYP24A1 Inhibitors 94
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids 88
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold 87
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 86
Potential role of two novel agonists of thyroid hormone receptor-β on liver regeneration 85
Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment 84
Hit-to-lead optimization of mouse Trace Amine Associated Receptor 1 (mTAAR1) agonists with a diphenylmethane-scaffold: Design, Synthesis, and biological study 83
Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation 79
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 78
Discovery of pyridoquinoxaline-based new P-gp inhibitors as coadjutant against Multi Drug Resistance in cancer 77
Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications 77
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease 76
Selective Thyroid Hormone Receptor-Beta (TRβ) Agonists: New Perspectives for the Treatment of Metabolic and Neurodegenerative Disorders 76
New Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective 75
Multi-targeted ChEI-copper chelating molecules as neuroprotective agents 74
Hydrogen sulfide: A worthwhile tool in the design of new multitarget drugs 74
Symbiotic approach applied to the synthesis of new agents for the treatment of Alzheimer’s disease 72
Epibatidine: A Promising Natural Alkaloid in Health 71
Memantine prodrug as a new agent for alzheimer’s disease 70
New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection 68
Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease 66
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. 66
Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer 63
Multi-Target Mechanisms of Phytochemicals in Alzheimer's Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation 51
Totale 4.933
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Categoria #
all - tutte 21.112
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.112
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021154 0 0 0 0 0 2 41 0 43 44 8 16
2021/2022297 24 10 2 9 11 17 5 13 32 18 25 131
2022/2023675 69 81 85 102 38 105 0 71 88 9 17 10
2023/2024231 34 12 6 3 87 17 0 8 0 10 27 27
2024/20251.727 12 19 94 44 91 56 148 335 566 229 91 42
2025/20261.723 146 554 278 306 306 133 0 0 0 0 0 0
Totale 4.933