IRIS
SESTITO, Simona
 Distribuzione geografica
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Continente #
NA - Nord America 2.755
AS - Asia 1.471
SA - Sud America 874
EU - Europa 544
Continente sconosciuto - Info sul continente non disponibili 76
AF - Africa 50
OC - Oceania 3
Totale 5.773
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Nazione #
US - Stati Uniti d'America 2.696
BR - Brasile 762
SG - Singapore 755
CN - Cina 237
HK - Hong Kong 144
DE - Germania 123
UA - Ucraina 115
VN - Vietnam 90
IT - Italia 76
FR - Francia 61
AR - Argentina 43
GB - Regno Unito 40
TR - Turchia 31
IN - India 29
BD - Bangladesh 24
IQ - Iraq 24
CA - Canada 23
RU - Federazione Russa 21
KR - Corea 19
BE - Belgio 18
UZ - Uzbekistan 17
VE - Venezuela 17
JP - Giappone 16
PK - Pakistan 16
MX - Messico 15
SE - Svezia 15
ZA - Sudafrica 14
PL - Polonia 13
EC - Ecuador 12
FI - Finlandia 11
NL - Olanda 11
CO - Colombia 10
ES - Italia 10
ID - Indonesia 10
EG - Egitto 8
PY - Paraguay 7
UY - Uruguay 7
AE - Emirati Arabi Uniti 6
JO - Giordania 6
KE - Kenya 6
PE - Perù 6
TN - Tunisia 6
CL - Cile 5
DZ - Algeria 5
MA - Marocco 5
AT - Austria 4
EU - Europa 4
HN - Honduras 4
IL - Israele 4
JM - Giamaica 4
LB - Libano 4
NP - Nepal 4
AU - Australia 3
BO - Bolivia 3
CZ - Repubblica Ceca 3
DO - Repubblica Dominicana 3
GE - Georgia 3
KG - Kirghizistan 3
MY - Malesia 3
OM - Oman 3
PT - Portogallo 3
RO - Romania 3
RS - Serbia 3
SA - Arabia Saudita 3
BA - Bosnia-Erzegovina 2
BG - Bulgaria 2
BN - Brunei Darussalam 2
BY - Bielorussia 2
CR - Costa Rica 2
DK - Danimarca 2
GA - Gabon 2
IR - Iran 2
KW - Kuwait 2
KZ - Kazakistan 2
PA - Panama 2
PR - Porto Rico 2
PS - Palestinian Territory 2
XK - ???statistics.table.value.countryCode.XK??? 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
AZ - Azerbaigian 1
BH - Bahrain 1
CG - Congo 1
CH - Svizzera 1
CI - Costa d'Avorio 1
GR - Grecia 1
GT - Guatemala 1
GY - Guiana 1
HT - Haiti 1
KH - Cambogia 1
LT - Lituania 1
MK - Macedonia 1
MM - Myanmar 1
MN - Mongolia 1
MU - Mauritius 1
NG - Nigeria 1
NI - Nicaragua 1
NO - Norvegia 1
QA - Qatar 1
SR - Suriname 1
Totale 5.699
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Città #
Dallas 705
Singapore 496
Chandler 462
San Jose 227
Ashburn 155
Hong Kong 141
Beijing 99
New York 98
Princeton 80
Council Bluffs 73
Columbus 70
São Paulo 55
Ann Arbor 48
Wilmington 41
Lauterbourg 37
Jacksonville 32
Santa Clara 31
Ho Chi Minh City 29
Shanghai 29
Belo Horizonte 26
Los Angeles 26
The Dalles 26
Hanoi 25
Rio de Janeiro 20
Boardman 18
Seoul 17
Brasília 16
Brussels 16
Falls Church 16
Tashkent 16
Tokyo 16
San Francisco 15
Mountain View 14
Orem 14
Baghdad 13
Warsaw 13
Curitiba 12
Porto Alegre 12
Düsseldorf 11
Frankfurt am Main 11
London 11
Munich 11
Phoenix 11
Sassari 11
Ankara 10
Jakarta 10
West Jordan 10
Poplar 9
Recife 9
Atlanta 8
Campinas 8
Istanbul 8
Norwalk 8
Amsterdam 7
Boston 7
Brooklyn 7
Buenos Aires 7
Buffalo 7
Cagliari 7
Denver 7
Montreal 7
Presidente Prudente 7
Salvador 7
São Gonçalo 7
Toronto 7
Alvorada 6
Cairo 6
Chennai 6
Fortaleza 6
Franca 6
Helsinki 6
Indaiatuba 6
Montevideo 6
Mumbai 6
Verona 6
Amman 5
Antonimina 5
Asunción 5
Balneário Camboriú 5
Cape Town 5
Caracas 5
Duque de Caxias 5
Guarulhos 5
Johannesburg 5
Lima 5
Medellín 5
Nairobi 5
Praia Grande 5
Ribeirão Preto 5
Romola 5
Santa Maria 5
São José do Rio Preto 5
Bragança Paulista 4
Cabo Frio 4
Canoas 4
Caraguatatuba 4
Contagem 4
Dhaka 4
Erbil 4
Islamabad 4
Totale 3.646
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Nome #
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DI PDK1 202
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs) 200
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) 196
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DUALI DI PDK1/AurA” 186
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA 186
H2S-BASED THERAPEUTIC AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES 178
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease? 172
Design, Synthesis, and Antiviral Activities of New Benzotriazole-Based Derivatives 171
Design, synthesis, and biological screening of a series of 4′-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) 166
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 157
Antibiotics and Carbohydrate-Containing Drugs Targeting Bacterial Cell Envelopes: An Overview 155
A patent update on PDK1 inhibitors (2015-present) 155
Inhibition of Enterovirus A71 by a Novel 2-Phenyl-Benzimidazole Derivative 155
ACE2 in the Era of SARS-CoV-2: Controversies and Novel Perspectives 137
Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics 134
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 134
3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome? 133
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis 132
Synthesis and pharmacological characterization of mitochondrial KATP channel openers with enhanced mitochondriotropic effects 129
Areca catechu—From farm to food and biomedical applications 125
Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease 121
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 120
Endogenous 3-iodothyronamine (T1Am) and synthetic thyronamine-like analog SG-2 act as novel pleiotropic neuroprotective agents through the modulation of SIRT6 112
Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D‐Like CYP24A1 Inhibitors 109
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 109
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold 106
Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation 100
Discovery of pyridoquinoxaline-based new P-gp inhibitors as coadjutant against Multi Drug Resistance in cancer 99
Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications 99
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids 97
Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment 96
Potential role of two novel agonists of thyroid hormone receptor-β on liver regeneration 96
Hit-to-lead optimization of mouse Trace Amine Associated Receptor 1 (mTAAR1) agonists with a diphenylmethane-scaffold: Design, Synthesis, and biological study 95
Selective Thyroid Hormone Receptor-Beta (TRβ) Agonists: New Perspectives for the Treatment of Metabolic and Neurodegenerative Disorders 94
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 94
New Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective 93
Epibatidine: A Promising Natural Alkaloid in Health 91
Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease 88
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease 87
Multi-targeted ChEI-copper chelating molecules as neuroprotective agents 85
New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection 85
Symbiotic approach applied to the synthesis of new agents for the treatment of Alzheimer’s disease 85
Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer 84
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. 84
Hydrogen sulfide: A worthwhile tool in the design of new multitarget drugs 83
Memantine prodrug as a new agent for alzheimer’s disease 80
Multi-Target Mechanisms of Phytochemicals in Alzheimer's Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation 61
Anticancer potential of decursin, decursinol angelate, and decursinol from Angelica gigas Nakai: A comprehensive review and future therapeutic prospects 17
Totale 5.773
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Categoria #
all - tutte 24.738
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.738
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022273 0 10 2 9 11 17 5 13 32 18 25 131
2022/2023675 69 81 85 102 38 105 0 71 88 9 17 10
2023/2024231 34 12 6 3 87 17 0 8 0 10 27 27
2024/20251.727 12 19 94 44 91 56 148 335 566 229 91 42
2025/20262.411 146 554 278 306 306 135 334 58 100 120 60 14
2026/2027152 28 124 0 0 0 0 0 0 0 0 0 0
Totale 5.773