IRIS
SESTITO, Simona
 Distribuzione geografica
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Continente #
NA - Nord America 1.096
EU - Europa 265
AS - Asia 15
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 2
SA - Sud America 1
Totale 1.384
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Nazione #
US - Stati Uniti d'America 1.093
UA - Ucraina 104
DE - Germania 83
IT - Italia 23
BE - Belgio 14
FR - Francia 12
SE - Svezia 11
IN - India 7
EU - Europa 4
FI - Finlandia 4
CA - Canada 3
RU - Federazione Russa 3
AU - Australia 2
GB - Regno Unito 2
IR - Iran 2
RO - Romania 2
TR - Turchia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BG - Bulgaria 1
BR - Brasile 1
DK - Danimarca 1
ES - Italia 1
GR - Grecia 1
HK - Hong Kong 1
KH - Cambogia 1
MN - Mongolia 1
NL - Olanda 1
NO - Norvegia 1
PK - Pakistan 1
RS - Serbia 1
Totale 1.384
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Città #
Chandler 463
New York 80
Princeton 80
Ann Arbor 48
Wilmington 41
Jacksonville 32
Ashburn 17
Falls Church 16
Mountain View 15
Brussels 12
West Jordan 10
Norwalk 8
San Francisco 7
Sassari 7
Helsinki 4
Mumbai 4
Seattle 3
Washington 3
Frankfurt am Main 2
Leuven 2
Pittsburgh 2
Rome 2
Serra 2
Toronto 2
Barcelona 1
Belgrade 1
Brisbane 1
Central 1
Chelyabinsk 1
Frankenthal 1
Geelong 1
Hanover 1
Huizen 1
Islamabad 1
London 1
Moncalieri 1
Montecatini Terme 1
Montemarciano 1
Napoli 1
New Delhi 1
Nuoro 1
Oslo 1
Paris 1
Phnom Penh 1
Redwood City 1
Rockville 1
Saratov 1
Sofia 1
Thessaloníki 1
Ulaanbaatar 1
Verona 1
Totale 889
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Nome #
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) 56
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA 50
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DI PDK1 50
H2S-BASED THERAPEUTIC AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES 48
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DUALI DI PDK1/AurA” 47
Inhibition of Enterovirus A71 by a Novel 2-Phenyl-Benzimidazole Derivative 47
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 47
Synthesis and pharmacological characterization of mitochondrial KATP channel openers with enhanced mitochondriotropic effects 45
A patent update on PDK1 inhibitors (2015-present) 44
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 39
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 38
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis 38
Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D‐Like CYP24A1 Inhibitors 37
New Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective 37
Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease 36
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs) 35
New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection 33
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease 33
Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications 33
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold 32
Symbiotic approach applied to the synthesis of new agents for the treatment of Alzheimer’s disease 32
Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation 32
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease? 31
Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease 31
Hit-to-lead optimization of mouse Trace Amine Associated Receptor 1 (mTAAR1) agonists with a diphenylmethane-scaffold: Design, Synthesis, and biological study 31
Potential role of two novel agonists of thyroid hormone receptor-β on liver regeneration 30
Multi-targeted ChEI-copper chelating molecules as neuroprotective agents 30
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 30
Endogenous 3-iodothyronamine (T1Am) and synthetic thyronamine-like analog SG-2 act as novel pleiotropic neuroprotective agents through the modulation of SIRT6 30
Hydrogen sulfide: A worthwhile tool in the design of new multitarget drugs 30
Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer 29
3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome? 28
Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics 27
ACE2 in the Era of SARS-CoV-2: Controversies and Novel Perspectives 27
Areca catechu—From farm to food and biomedical applications 27
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 26
Epibatidine: A Promising Natural Alkaloid in Health 24
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. 23
Selective Thyroid Hormone Receptor-Beta (TRβ) Agonists: New Perspectives for the Treatment of Metabolic and Neurodegenerative Disorders 20
Design, synthesis, and biological screening of a series of 4′-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) 18
Memantine prodrug as a new agent for alzheimer’s disease 14
Design, synthesis, and biological screening of a series of 4 '-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) 13
Design, Synthesis, and Antiviral Activities of New Benzotriazole-Based Derivatives 12
Antibiotics and Carbohydrate-Containing Drugs Targeting Bacterial Cell Envelopes: An Overview 11
Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment 9
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids 6
Multi-Target Mechanisms of Phytochemicals in Alzheimer's Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation 1
Totale 1.447
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Categoria #
all - tutte 7.927
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 7.927
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021280 0 0 82 3 41 2 41 0 43 44 8 16
2021/2022297 24 10 2 9 11 17 5 13 32 18 25 131
2022/2023684 69 81 85 106 38 106 1 73 88 9 18 10
2023/2024186 34 12 8 3 91 19 0 9 0 10 0 0
Totale 1.447