IRIS
SESTITO, Simona
 Distribuzione geografica
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Continente #
NA - Nord America 1.111
EU - Europa 269
AS - Asia 44
Continente sconosciuto - Info sul continente non disponibili 5
OC - Oceania 2
SA - Sud America 1
Totale 1.432
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Nazione #
US - Stati Uniti d'America 1.108
UA - Ucraina 104
DE - Germania 84
IT - Italia 25
SG - Singapore 15
BE - Belgio 14
KR - Corea 14
FR - Francia 12
SE - Svezia 11
IN - India 7
EU - Europa 4
FI - Finlandia 4
CA - Canada 3
RU - Federazione Russa 3
AU - Australia 2
CZ - Repubblica Ceca 2
GB - Regno Unito 2
IR - Iran 2
RO - Romania 2
TR - Turchia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BG - Bulgaria 1
BR - Brasile 1
DK - Danimarca 1
GR - Grecia 1
HK - Hong Kong 1
KH - Cambogia 1
MN - Mongolia 1
NL - Olanda 1
NO - Norvegia 1
PK - Pakistan 1
RS - Serbia 1
Totale 1.432
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Città #
Chandler 462
Princeton 80
New York 76
Ann Arbor 48
Wilmington 41
Jacksonville 32
Boardman 18
Ashburn 17
Falls Church 16
Mountain View 14
Seoul 14
Brussels 12
Singapore 12
Sassari 11
West Jordan 10
Norwalk 8
San Francisco 7
Helsinki 4
Mumbai 4
Washington 3
Brno 2
Leuven 2
Munich 2
Pittsburgh 2
Seattle 2
Serra 2
Toronto 2
Belgrade 1
Brisbane 1
Central 1
Chelyabinsk 1
Council Bluffs 1
Forest City 1
Frankenthal 1
Frankfurt am Main 1
Geelong 1
Hanover 1
Huizen 1
Islamabad 1
London 1
Moncalieri 1
Montecatini Terme 1
Montemarciano 1
Napoli 1
New Delhi 1
Oslo 1
Paris 1
Phnom Penh 1
Redwood City 1
Rockville 1
Saratov 1
Sofia 1
Thessaloníki 1
Ulaanbaatar 1
Verona 1
Totale 931
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Nome #
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) 58
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DI PDK1 54
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA 53
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 50
H2S-BASED THERAPEUTIC AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES 50
Inhibition of Enterovirus A71 by a Novel 2-Phenyl-Benzimidazole Derivative 49
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DUALI DI PDK1/AurA” 48
A patent update on PDK1 inhibitors (2015-present) 47
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 45
Synthesis and pharmacological characterization of mitochondrial KATP channel openers with enhanced mitochondriotropic effects 45
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 40
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis 40
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs) 39
Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D‐Like CYP24A1 Inhibitors 38
New Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective 37
Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease 36
Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications 34
New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection 33
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease 33
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold 32
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease? 32
Symbiotic approach applied to the synthesis of new agents for the treatment of Alzheimer’s disease 32
Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation 32
Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease 31
Hit-to-lead optimization of mouse Trace Amine Associated Receptor 1 (mTAAR1) agonists with a diphenylmethane-scaffold: Design, Synthesis, and biological study 31
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 31
Endogenous 3-iodothyronamine (T1Am) and synthetic thyronamine-like analog SG-2 act as novel pleiotropic neuroprotective agents through the modulation of SIRT6 31
Potential role of two novel agonists of thyroid hormone receptor-β on liver regeneration 30
Multi-targeted ChEI-copper chelating molecules as neuroprotective agents 30
ACE2 in the Era of SARS-CoV-2: Controversies and Novel Perspectives 30
Hydrogen sulfide: A worthwhile tool in the design of new multitarget drugs 30
Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics 29
Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer 29
3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome? 29
Areca catechu—From farm to food and biomedical applications 28
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 27
Epibatidine: A Promising Natural Alkaloid in Health 24
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. 23
Selective Thyroid Hormone Receptor-Beta (TRβ) Agonists: New Perspectives for the Treatment of Metabolic and Neurodegenerative Disorders 20
Design, Synthesis, and Antiviral Activities of New Benzotriazole-Based Derivatives 17
Antibiotics and Carbohydrate-Containing Drugs Targeting Bacterial Cell Envelopes: An Overview 16
Design, synthesis, and biological screening of a series of 4′-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) 16
Memantine prodrug as a new agent for alzheimer’s disease 14
Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment 11
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids 9
Multi-Target Mechanisms of Phytochemicals in Alzheimer's Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation 2
Totale 1.495
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Categoria #
all - tutte 9.485
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 9.485
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021280 0 0 82 3 41 2 41 0 43 44 8 16
2021/2022297 24 10 2 9 11 17 5 13 32 18 25 131
2022/2023675 69 81 85 102 38 105 0 71 88 9 17 10
2023/2024231 34 12 6 3 87 17 0 8 0 10 27 27
2024/202512 12 0 0 0 0 0 0 0 0 0 0 0
Totale 1.495