IRIS
SESTITO, Simona
 Distribuzione geografica
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Continente #
NA - Nord America 2.238
AS - Asia 1.189
SA - Sud America 844
EU - Europa 441
AF - Africa 42
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 2
Totale 4.763
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Nazione #
US - Stati Uniti d'America 2.195
BR - Brasile 745
SG - Singapore 652
CN - Cina 188
HK - Hong Kong 126
DE - Germania 114
UA - Ucraina 114
IT - Italia 52
AR - Argentina 41
GB - Regno Unito 31
TR - Turchia 28
VN - Vietnam 25
IN - India 24
FR - Francia 22
IQ - Iraq 22
RU - Federazione Russa 21
CA - Canada 19
KR - Corea 17
BD - Bangladesh 16
BE - Belgio 15
UZ - Uzbekistan 14
SE - Svezia 13
VE - Venezuela 13
PK - Pakistan 12
EC - Ecuador 11
FI - Finlandia 11
MX - Messico 11
ID - Indonesia 10
PL - Polonia 10
ZA - Sudafrica 10
JP - Giappone 9
CO - Colombia 8
EG - Egitto 7
NL - Olanda 7
PY - Paraguay 7
AE - Emirati Arabi Uniti 6
ES - Italia 6
KE - Kenya 6
UY - Uruguay 6
DZ - Algeria 5
MA - Marocco 5
PE - Perù 5
TN - Tunisia 5
CL - Cile 4
EU - Europa 4
IL - Israele 4
JO - Giordania 4
AT - Austria 3
CZ - Repubblica Ceca 3
GE - Georgia 3
HN - Honduras 3
KG - Kirghizistan 3
NP - Nepal 3
RO - Romania 3
RS - Serbia 3
AU - Australia 2
BA - Bosnia-Erzegovina 2
BG - Bulgaria 2
BN - Brunei Darussalam 2
BO - Bolivia 2
BY - Bielorussia 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
GA - Gabon 2
IR - Iran 2
JM - Giamaica 2
KW - Kuwait 2
KZ - Kazakistan 2
LB - Libano 2
OM - Oman 2
PA - Panama 2
PS - Palestinian Territory 2
XK - ???statistics.table.value.countryCode.XK??? 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
AZ - Azerbaigian 1
BH - Bahrain 1
CI - Costa d'Avorio 1
CR - Costa Rica 1
GR - Grecia 1
GT - Guatemala 1
GY - Guiana 1
KH - Cambogia 1
LT - Lituania 1
MK - Macedonia 1
MM - Myanmar 1
MN - Mongolia 1
NG - Nigeria 1
NI - Nicaragua 1
NO - Norvegia 1
PR - Porto Rico 1
QA - Qatar 1
SA - Arabia Saudita 1
SR - Suriname 1
SY - Repubblica araba siriana 1
TJ - Tagikistan 1
Totale 4.763
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Città #
Dallas 699
Chandler 462
Singapore 406
Hong Kong 124
New York 93
Ashburn 92
Beijing 80
Princeton 80
São Paulo 51
Ann Arbor 48
Wilmington 41
Jacksonville 32
Shanghai 29
Belo Horizonte 26
The Dalles 26
Columbus 23
Los Angeles 23
Council Bluffs 20
Rio de Janeiro 20
Boardman 18
Seoul 17
Brasília 16
Falls Church 16
Santa Clara 15
Mountain View 14
Tashkent 14
Brussels 13
San Francisco 13
Baghdad 12
Curitiba 12
Porto Alegre 12
Düsseldorf 11
Munich 11
Sassari 11
Jakarta 10
Warsaw 10
West Jordan 10
Ankara 9
Ho Chi Minh City 9
Poplar 9
Tokyo 9
Campinas 8
Norwalk 8
Phoenix 8
Recife 8
Brooklyn 7
Buenos Aires 7
Cagliari 7
Denver 7
Hanoi 7
London 7
Montreal 7
Presidente Prudente 7
Salvador 7
São Gonçalo 7
Alvorada 6
Boston 6
Buffalo 6
Cairo 6
Fortaleza 6
Franca 6
Helsinki 6
Indaiatuba 6
Istanbul 6
Mumbai 6
Asunción 5
Duque de Caxias 5
Frankfurt am Main 5
Guarulhos 5
Montevideo 5
Nairobi 5
Praia Grande 5
Ribeirão Preto 5
Romola 5
Santa Maria 5
São José do Rio Preto 5
Toronto 5
Amman 4
Amsterdam 4
Atlanta 4
Balneário Camboriú 4
Bragança Paulista 4
Cabo Frio 4
Canoas 4
Cape Town 4
Caraguatatuba 4
Chennai 4
Contagem 4
Dhaka 4
Erbil 4
Lahore 4
Lima 4
Manaus 4
Maringá 4
Medellín 4
Moscow 4
Osasco 4
Quito 4
Santo André 4
Sumaré 4
Totale 2.960
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Nome #
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs) 178
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) 176
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DI PDK1 175
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DUALI DI PDK1/AurA” 164
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA 159
H2S-BASED THERAPEUTIC AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES 155
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease? 147
Design, Synthesis, and Antiviral Activities of New Benzotriazole-Based Derivatives 143
Design, synthesis, and biological screening of a series of 4′-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) 140
A patent update on PDK1 inhibitors (2015-present) 139
Antibiotics and Carbohydrate-Containing Drugs Targeting Bacterial Cell Envelopes: An Overview 132
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 131
Inhibition of Enterovirus A71 by a Novel 2-Phenyl-Benzimidazole Derivative 129
ACE2 in the Era of SARS-CoV-2: Controversies and Novel Perspectives 118
Synthesis and pharmacological characterization of mitochondrial KATP channel openers with enhanced mitochondriotropic effects 118
Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics 116
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis 110
3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome? 107
Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease 107
Areca catechu—From farm to food and biomedical applications 105
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 103
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 102
Endogenous 3-iodothyronamine (T1Am) and synthetic thyronamine-like analog SG-2 act as novel pleiotropic neuroprotective agents through the modulation of SIRT6 94
Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D‐Like CYP24A1 Inhibitors 93
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids 87
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold 85
Potential role of two novel agonists of thyroid hormone receptor-β on liver regeneration 83
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 83
Hit-to-lead optimization of mouse Trace Amine Associated Receptor 1 (mTAAR1) agonists with a diphenylmethane-scaffold: Design, Synthesis, and biological study 82
Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment 81
Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation 77
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 76
Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications 76
Discovery of pyridoquinoxaline-based new P-gp inhibitors as coadjutant against Multi Drug Resistance in cancer 75
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease 75
Selective Thyroid Hormone Receptor-Beta (TRβ) Agonists: New Perspectives for the Treatment of Metabolic and Neurodegenerative Disorders 75
Hydrogen sulfide: A worthwhile tool in the design of new multitarget drugs 74
New Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective 73
Multi-targeted ChEI-copper chelating molecules as neuroprotective agents 72
Memantine prodrug as a new agent for alzheimer’s disease 70
Symbiotic approach applied to the synthesis of new agents for the treatment of Alzheimer’s disease 70
Epibatidine: A Promising Natural Alkaloid in Health 70
Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease 65
New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection 65
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. 65
Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer 61
Multi-Target Mechanisms of Phytochemicals in Alzheimer's Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation 50
Totale 4.831
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Categoria #
all - tutte 20.780
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.780
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021154 0 0 0 0 0 2 41 0 43 44 8 16
2021/2022297 24 10 2 9 11 17 5 13 32 18 25 131
2022/2023675 69 81 85 102 38 105 0 71 88 9 17 10
2023/2024231 34 12 6 3 87 17 0 8 0 10 27 27
2024/20251.727 12 19 94 44 91 56 148 335 566 229 91 42
2025/20261.621 146 554 278 306 306 31 0 0 0 0 0 0
Totale 4.831