IRIS
SESTITO, Simona
 Distribuzione geografica
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Continente #
NA - Nord America 1.138
EU - Europa 287
AS - Asia 223
Continente sconosciuto - Info sul continente non disponibili 5
SA - Sud America 4
OC - Oceania 2
Totale 1.659
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Nazione #
US - Stati Uniti d'America 1.135
SG - Singapore 155
UA - Ucraina 104
DE - Germania 87
CN - Cina 39
IT - Italia 39
BE - Belgio 14
KR - Corea 14
FR - Francia 12
SE - Svezia 11
IN - India 7
FI - Finlandia 5
BR - Brasile 4
EU - Europa 4
CA - Canada 3
RU - Federazione Russa 3
AU - Australia 2
CZ - Repubblica Ceca 2
GB - Regno Unito 2
IR - Iran 2
RO - Romania 2
TR - Turchia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BG - Bulgaria 1
DK - Danimarca 1
GR - Grecia 1
HK - Hong Kong 1
KH - Cambogia 1
MN - Mongolia 1
NL - Olanda 1
NO - Norvegia 1
PK - Pakistan 1
RS - Serbia 1
Totale 1.659
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Città #
Chandler 462
Singapore 125
Princeton 80
New York 76
Ann Arbor 48
Wilmington 41
Jacksonville 32
Boardman 18
Ashburn 17
Falls Church 16
Mountain View 14
Seoul 14
Brussels 12
Sassari 11
West Jordan 10
Beijing 8
Norwalk 8
San Francisco 7
Santa Clara 7
Dallas 5
Helsinki 5
Munich 5
Romola 5
Shanghai 5
Mumbai 4
Guangzhou 3
Washington 3
Brno 2
Jiaxing 2
Leuven 2
Pittsburgh 2
Seattle 2
Serra 2
Toronto 2
Altamira 1
Belgrade 1
Brasília 1
Brisbane 1
Central 1
Chelyabinsk 1
Contagem 1
Council Bluffs 1
Forest City 1
Frankenthal 1
Frankfurt am Main 1
Fuzhou 1
Geelong 1
Haining 1
Hanover 1
Huizen 1
Islamabad 1
London 1
Moncalieri 1
Montecatini Terme 1
Montemarciano 1
Napoli 1
New Delhi 1
Oslo 1
Paris 1
Phnom Penh 1
Quanzhou 1
Redwood City 1
Rockville 1
Saratov 1
Sofia 1
Thessaloníki 1
Ulaanbaatar 1
Verona 1
Wuhan 1
Totale 1.090
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Nome #
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) 69
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DI PDK1 64
H2S-BASED THERAPEUTIC AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES 59
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA 58
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DUALI DI PDK1/AurA” 56
Inhibition of Enterovirus A71 by a Novel 2-Phenyl-Benzimidazole Derivative 53
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 53
A patent update on PDK1 inhibitors (2015-present) 51
Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications 49
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 48
Synthesis and pharmacological characterization of mitochondrial KATP channel openers with enhanced mitochondriotropic effects 47
ACE2 in the Era of SARS-CoV-2: Controversies and Novel Perspectives 46
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs) 43
Areca catechu—From farm to food and biomedical applications 43
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis 43
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 41
Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease 41
Hit-to-lead optimization of mouse Trace Amine Associated Receptor 1 (mTAAR1) agonists with a diphenylmethane-scaffold: Design, Synthesis, and biological study 41
Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D‐Like CYP24A1 Inhibitors 38
New Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective 38
Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation 37
Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics 36
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease? 36
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold 35
New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection 35
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease 35
Hydrogen sulfide: A worthwhile tool in the design of new multitarget drugs 35
Multi-targeted ChEI-copper chelating molecules as neuroprotective agents 34
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 34
Potential role of two novel agonists of thyroid hormone receptor-β on liver regeneration 33
3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome? 33
Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease 33
Symbiotic approach applied to the synthesis of new agents for the treatment of Alzheimer’s disease 33
Endogenous 3-iodothyronamine (T1Am) and synthetic thyronamine-like analog SG-2 act as novel pleiotropic neuroprotective agents through the modulation of SIRT6 33
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 31
Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer 30
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. 27
Epibatidine: A Promising Natural Alkaloid in Health 27
Antibiotics and Carbohydrate-Containing Drugs Targeting Bacterial Cell Envelopes: An Overview 25
Selective Thyroid Hormone Receptor-Beta (TRβ) Agonists: New Perspectives for the Treatment of Metabolic and Neurodegenerative Disorders 25
Design, Synthesis, and Antiviral Activities of New Benzotriazole-Based Derivatives 21
Design, synthesis, and biological screening of a series of 4′-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) 21
Memantine prodrug as a new agent for alzheimer’s disease 15
Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment 13
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids 13
Multi-Target Mechanisms of Phytochemicals in Alzheimer's Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation 9
Discovery of pyridoquinoxaline-based new P-gp inhibitors as coadjutant against Multi Drug Resistance in cancer 3
Totale 1.723
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Categoria #
all - tutte 12.167
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 12.167
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021280 0 0 82 3 41 2 41 0 43 44 8 16
2021/2022297 24 10 2 9 11 17 5 13 32 18 25 131
2022/2023675 69 81 85 102 38 105 0 71 88 9 17 10
2023/2024231 34 12 6 3 87 17 0 8 0 10 27 27
2024/2025240 12 19 94 44 71 0 0 0 0 0 0 0
Totale 1.723