SESTITO, Simona

SESTITO, Simona  

SCIENZE CHIMICHE, FISICHE, MATEMATICHE E NATURALI  

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Titolo Data di pubblicazione Autore(i) File
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA 1-gen-2017 Sestito, S; Daniele, S; Martini, C; Rapposelli, S; Puricelli, G.
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) 1-gen-2018 Sestito, Simona; Daniele, Simona; Martini, Claudia; Rapposelli, Simona; Puricelli, Guido
3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome? 1-gen-2020 Rutigliano, Grazia; Bandini, Lavinia; Sestito, Simona; Chiellini, Grazia
ACE2 in the Era of SARS-CoV-2: Controversies and Novel Perspectives 1-gen-2020 Saponaro, F.; Rutigliano, G.; Sestito, S.; Bandini, L.; Storti, B.; Bizzarri, R.; Zucchi, R.
Areca catechu—From farm to food and biomedical applications 1-gen-2020 Salehi, B.; Konovalov, D. A.; Fru, P.; Kapewangolo, P.; Peron, G.; Ksenija, M. S.; Cardoso, S. M.; Pereira, O. R.; Nigam, M.; Nicola, S.; Pignata, G.; Rapposelli, S.; Sestito, S.; Anil Kumar, N. V.; de la Luz Cadiz-Gurrea, M.; Segura-Carretero, A.; P. Mishra, A.; Sharifi-Rad, M.; C. Cho, W.; Taheri, Y.; Setzer, W. N.; Sharifi-Rad, J.
Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics 1-gen-2020 Runfola, M.; Sestito, S.; Gul, S.; Chiellini, G.; Rapposelli, S.
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 1-gen-2015 Daniele, Simona; Costa, Barbara; Zappelli, Elisa; DA POZZO, Eleonora; Sestito, Simona; Nesi, Giulia; Campiglia, Pietro; Marinelli, Luciana; Novellino, Ettore; Rapposelli, Simona; Martini, Claudia
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DUALI DI PDK1/AurA” 1-gen-2016 Sestito, Simona; Daniele, Simona; Martini, Claudia; Rapposelli, Simona; Guido, Puricelli
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DI PDK1 1-gen-2015 Sestito, S.; Daniele, S.; Martini, C.; Rapposelli, S.; Puricelli, G.
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs) 1-gen-2021 Riu, F.; Sanna, L.; Ibba, R.; Piras, S.; Bordoni, V.; Scorciapino, M. A.; Lai, M.; Sestito, S.; Bagella, L.; Carta, A.
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 1-gen-2015 Sestito, Simona; Nesi, Giulia; Daniele, Simona; Martelli, Alma; Digiacomo, Maria; Borghini, Alice; Pietra, Daniele; Calderone, Vincenzo; Lapucci, Annalina; Falasca, Marco; Parrella, Paola; Notarangelo, Angelantonio; Breschi, MARIA CRISTINA; Macchia, Marco; Martini, Claudia; Rapposelli, Simona
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease? 1-gen-2019 Sestito, S.; Pruccoli, L.; Runfola, M.; Citi, V.; Martelli, A.; Saccomanni, G.; Calderone, V.; Tarozzi, A.; Rapposelli, S.
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis 1-gen-2020 Runfola, Massimiliano; Sestito, Simona; Bellusci, Lorenza; La Pietra, Valeria; D'Amore, Vincenzo Maria; Kowalik, Marta Anna; Chiellini, Grazia; Gul, Sheraz; Perra, Andrea; Columbano, Amedeo; Marinelli, Luciana; Novellino, Ettore; Rapposelli, Simona
Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease 1-gen-2017 Chen, Ziwei; Digiacomo, Maria; Tu, Yalin; Gu, Qiong; Wang, Shengnan; Yang, Xiaohong; Chu, Jiaqi; Chen, Qiuhe; Han, Yifan; Chen, Jingkao; Nesi, Giulia; Sestito, Simona; Macchia, Marco; Rapposelli, Simona; Pi, Rongbiao
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 1-gen-2017 Daniele, Simona; Sestito, Simona; Pietrobono, Deborah; Giacomelli, Chiara; Chiellini, Grazia; Di Maio, Danilo; Marinelli, Luciana; Novellino, Ettore; Martini, Claudia; Rapposelli, Simona
Dual PDK1/aurora kinase a inhibitors reduce pancreatic cancer cell proliferation and colony formation 1-gen-2019 Casari, I.; Domenichini, A.; Sestito, S.; Capone, E.; Sala, G.; Rapposelli, S.; Falasca, M.
Endogenous 3-iodothyronamine (T1Am) and synthetic thyronamine-like analog SG-2 act as novel pleiotropic neuroprotective agents through the modulation of SIRT6 1-gen-2020 Bellusci, L.; Runfola, M.; Carnicelli, V.; Sestito, S.; Fulceri, F.; Santucci, F.; Lenzi, P.; Fornai, F.; Rapposelli, S.; Origlia, N.; Zucchi, R.; Chiellini, G.
Epibatidine: A Promising Natural Alkaloid in Health 1-gen-2019 Salehi, Bahare; Sestito, Simona; Rapposelli, Simona; Peron, Gregorio; Calina, Daniela; Sharifi-Rad, Mehdi; Sharopov, Farukh; Martins, Natália; Sharifi-Rad, Javad
H2S-BASED THERAPEUTIC AGENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES 1-gen-2019 Calderone, Vincenzo; Puricelli, Guido; Rapposelli, Simona; Sestito, Simona
Hit-to-lead optimization of mouse Trace Amine Associated Receptor 1 (mTAAR1) agonists with a diphenylmethane-scaffold: Design, Synthesis, and biological study 1-gen-2016 Chiellini, Grazia; Nesi, Giulia; Sestito, Simona; Chiarugi, S; Runfola, M; Espinoza, S; Sabatini, Martina; Bellusci, L; Laurino, A; Cichero, E; Gainetdinov, Rr; Fossa, P; Raimondi, L; Zucchi, Riccardo; Rapposelli, Simona