SESTITO, Simona
SESTITO, Simona
SCIENZE CHIMICHE, FISICHE, MATEMATICHE E NATURALI
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA
2017-01-01 Sestito, S; Daniele, S; Martini, C; Rapposelli, S; Puricelli, G.
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018)
2018-01-01 Sestito, Simona; Daniele, Simona; Martini, Claudia; Rapposelli, Simona; Puricelli, Guido
3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome?
2020-01-01 Rutigliano, Grazia; Bandini, Lavinia; Sestito, Simona; Chiellini, Grazia
A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs)
2021-01-01 Riu, F.; Sanna, L.; Ibba, R.; Piras, S.; Bordoni, V.; Scorciapino, M. A.; Lai, M.; Sestito, S.; Bagella, L.; Carta, A.
A patent update on PDK1 inhibitors (2015-present)
2019-01-01 Sestito, S.; Rapposelli, S.
ACE2 in the Era of SARS-CoV-2: Controversies and Novel Perspectives
2020-01-01 Saponaro, F.; Rutigliano, G.; Sestito, S.; Bandini, L.; Storti, B.; Bizzarri, R.; Zucchi, R.
Antibiotics and Carbohydrate-Containing Drugs Targeting Bacterial Cell Envelopes: An Overview
2022-01-01 Riu, Federico; Ruda, Alessandro; Ibba, Roberta; Sestito, Simona; Lupinu, Ilenia; Piras, Sandra; Widmalm, Göran; Carta, Antonio
Areca catechu—From farm to food and biomedical applications
2020-01-01 Salehi, B.; Konovalov, D. A.; Fru, P.; Kapewangolo, P.; Peron, G.; Ksenija, M. S.; Cardoso, S. M.; Pereira, O. R.; Nigam, M.; Nicola, S.; Pignata, G.; Rapposelli, S.; Sestito, S.; Anil Kumar, N. V.; de la Luz Cadiz-Gurrea, M.; Segura-Carretero, A.; P. Mishra, A.; Sharifi-Rad, M.; C. Cho, W.; Taheri, Y.; Setzer, W. N.; Sharifi-Rad, J.
Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment
2021-01-01 Sharifi-Rad, Javad; Quispe, Cristina; Butnariu, Monica; Rotariu, Lia Sanda; Sytar, Oksana; Sestito, Simona; Rapposelli, Simona; Akram, Muhammad; Iqbal, Mehwish; Krishna, Akash; Kumar, Nanjangud Venkatesh Anil; Braga, Susana S; Cardoso, Susana M; Jafernik, Karolina; Ekiert, Halina; Cruz-Martins, Natália; Szopa, Agnieszka; Villagran, Marcelo; Mardones, Lorena; Martorell, Miquel; Docea, Anca Oana; Calina, Daniela
Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics
2020-01-01 Runfola, M.; Sestito, S.; Gul, S.; Chiellini, G.; Rapposelli, S.
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells
2015-01-01 Daniele, Simona; Costa, Barbara; Zappelli, Elisa; DA POZZO, Eleonora; Sestito, Simona; Nesi, Giulia; Campiglia, Pietro; Marinelli, Luciana; Novellino, Ettore; Rapposelli, Simona; Martini, Claudia
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DUALI DI PDK1/AurA”
2016-01-01 Sestito, Simona; Daniele, Simona; Martini, Claudia; Rapposelli, Simona; Guido, Puricelli
COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DI PDK1
2015-01-01 Sestito, S.; Daniele, S.; Martini, C.; Rapposelli, S.; Puricelli, G.
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme
2015-01-01 Sestito, Simona; Nesi, Giulia; Daniele, Simona; Martelli, Alma; Digiacomo, Maria; Borghini, Alice; Pietra, Daniele; Calderone, Vincenzo; Lapucci, Annalina; Falasca, Marco; Parrella, Paola; Notarangelo, Angelantonio; Breschi, MARIA CRISTINA; Macchia, Marco; Martini, Claudia; Rapposelli, Simona
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease?
2019-01-01 Sestito, S.; Pruccoli, L.; Runfola, M.; Citi, V.; Martelli, A.; Saccomanni, G.; Calderone, V.; Tarozzi, A.; Rapposelli, S.
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis
2020-01-01 Runfola, Massimiliano; Sestito, Simona; Bellusci, Lorenza; La Pietra, Valeria; D'Amore, Vincenzo Maria; Kowalik, Marta Anna; Chiellini, Grazia; Gul, Sheraz; Perra, Andrea; Columbano, Amedeo; Marinelli, Luciana; Novellino, Ettore; Rapposelli, Simona
Design, Synthesis, and Antiviral Activities of New Benzotriazole-Based Derivatives
2023-01-01 Ibba, Roberta; Corona, Paola; Nonne, Francesca; Caria, Paola; Serreli, Gabriele; Palmas, Vanessa; Riu, Federico; Sestito, Simona; Nieddu, Maria; Loddo, Roberta; Sanna, Giuseppina; Piras, Sandra; Carta, Antonio
Design, synthesis, and biological screening of a series of 4′-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs)
2022-01-01 Riu, F; Ibba, R; Zoroddu, S; Sestito, S; Lai, M; Piras, S; Sanna, L; Bordoni, V; Bagella, L; Carta, A
Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids
2022-01-01 Bacci, Andrea; Corsi, Francesca; Runfola, Massimiliano; Sestito, Simona; Piano, Ilaria; Manera, Clementina; Saccomanni, Giuseppe; Gargini, Claudia; Rapposelli, Simona
Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease
2017-01-01 Chen, Ziwei; Digiacomo, Maria; Tu, Yalin; Gu, Qiong; Wang, Shengnan; Yang, Xiaohong; Chu, Jiaqi; Chen, Qiuhe; Han, Yifan; Chen, Jingkao; Nesi, Giulia; Sestito, Simona; Macchia, Marco; Rapposelli, Simona; Pi, Rongbiao
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA | 1-gen-2017 | Sestito, S; Daniele, S; Martini, C; Rapposelli, S; Puricelli, G. | |
| 2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) | 1-gen-2018 | Sestito, Simona; Daniele, Simona; Martini, Claudia; Rapposelli, Simona; Puricelli, Guido | |
| 3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome? | 1-gen-2020 | Rutigliano, Grazia; Bandini, Lavinia; Sestito, Simona; Chiellini, Grazia | |
| A comprehensive assessment of a new series of 5′,6′-difluorobenzotriazole-acrylonitrile derivatives as microtubule targeting agents (MTAs) | 1-gen-2021 | Riu, F.; Sanna, L.; Ibba, R.; Piras, S.; Bordoni, V.; Scorciapino, M. A.; Lai, M.; Sestito, S.; Bagella, L.; Carta, A. | |
| A patent update on PDK1 inhibitors (2015-present) | 1-gen-2019 | Sestito, S.; Rapposelli, S. | |
| ACE2 in the Era of SARS-CoV-2: Controversies and Novel Perspectives | 1-gen-2020 | Saponaro, F.; Rutigliano, G.; Sestito, S.; Bandini, L.; Storti, B.; Bizzarri, R.; Zucchi, R. | |
| Antibiotics and Carbohydrate-Containing Drugs Targeting Bacterial Cell Envelopes: An Overview | 1-gen-2022 | Riu, Federico; Ruda, Alessandro; Ibba, Roberta; Sestito, Simona; Lupinu, Ilenia; Piras, Sandra; Widmalm, Göran; Carta, Antonio | |
| Areca catechu—From farm to food and biomedical applications | 1-gen-2020 | Salehi, B.; Konovalov, D. A.; Fru, P.; Kapewangolo, P.; Peron, G.; Ksenija, M. S.; Cardoso, S. M.; Pereira, O. R.; Nigam, M.; Nicola, S.; Pignata, G.; Rapposelli, S.; Sestito, S.; Anil Kumar, N. V.; de la Luz Cadiz-Gurrea, M.; Segura-Carretero, A.; P. Mishra, A.; Sharifi-Rad, M.; C. Cho, W.; Taheri, Y.; Setzer, W. N.; Sharifi-Rad, J. | |
| Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment | 1-gen-2021 | Sharifi-Rad, Javad; Quispe, Cristina; Butnariu, Monica; Rotariu, Lia Sanda; Sytar, Oksana; Sestito, Simona; Rapposelli, Simona; Akram, Muhammad; Iqbal, Mehwish; Krishna, Akash; Kumar, Nanjangud Venkatesh Anil; Braga, Susana S; Cardoso, Susana M; Jafernik, Karolina; Ekiert, Halina; Cruz-Martins, Natália; Szopa, Agnieszka; Villagran, Marcelo; Mardones, Lorena; Martorell, Miquel; Docea, Anca Oana; Calina, Daniela | |
| Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics | 1-gen-2020 | Runfola, M.; Sestito, S.; Gul, S.; Chiellini, G.; Rapposelli, S. | |
| Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells | 1-gen-2015 | Daniele, Simona; Costa, Barbara; Zappelli, Elisa; DA POZZO, Eleonora; Sestito, Simona; Nesi, Giulia; Campiglia, Pietro; Marinelli, Luciana; Novellino, Ettore; Rapposelli, Simona; Martini, Claudia | |
| COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DUALI DI PDK1/AurA” | 1-gen-2016 | Sestito, Simona; Daniele, Simona; Martini, Claudia; Rapposelli, Simona; Guido, Puricelli | |
| COMPOSTI 2-OXO-1,2-DIIDROPIRIDIN-3-CARBOSSAMMIDE E LORO USO COME INIBITORI DI PDK1 | 1-gen-2015 | Sestito, S.; Daniele, S.; Martini, C.; Rapposelli, S.; Puricelli, G. | |
| Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme | 1-gen-2015 | Sestito, Simona; Nesi, Giulia; Daniele, Simona; Martelli, Alma; Digiacomo, Maria; Borghini, Alice; Pietra, Daniele; Calderone, Vincenzo; Lapucci, Annalina; Falasca, Marco; Parrella, Paola; Notarangelo, Angelantonio; Breschi, MARIA CRISTINA; Macchia, Marco; Martini, Claudia; Rapposelli, Simona | |
| Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease? | 1-gen-2019 | Sestito, S.; Pruccoli, L.; Runfola, M.; Citi, V.; Martelli, A.; Saccomanni, G.; Calderone, V.; Tarozzi, A.; Rapposelli, S. | |
| Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis | 1-gen-2020 | Runfola, Massimiliano; Sestito, Simona; Bellusci, Lorenza; La Pietra, Valeria; D'Amore, Vincenzo Maria; Kowalik, Marta Anna; Chiellini, Grazia; Gul, Sheraz; Perra, Andrea; Columbano, Amedeo; Marinelli, Luciana; Novellino, Ettore; Rapposelli, Simona | |
| Design, Synthesis, and Antiviral Activities of New Benzotriazole-Based Derivatives | 1-gen-2023 | Ibba, Roberta; Corona, Paola; Nonne, Francesca; Caria, Paola; Serreli, Gabriele; Palmas, Vanessa; Riu, Federico; Sestito, Simona; Nieddu, Maria; Loddo, Roberta; Sanna, Giuseppina; Piras, Sandra; Carta, Antonio | |
| Design, synthesis, and biological screening of a series of 4′-fluoro-benzotriazole-acrylonitrile derivatives as microtubule-destabilising agents (MDAs) | 1-gen-2022 | Riu, F; Ibba, R; Zoroddu, S; Sestito, S; Lai, M; Piras, S; Sanna, L; Bordoni, V; Bagella, L; Carta, A | |
| Design, Synthesis, and In Vitro Evaluation of Novel 8-Amino-Quinoline Combined with Natural Antioxidant Acids | 1-gen-2022 | Bacci, Andrea; Corsi, Francesca; Runfola, Massimiliano; Sestito, Simona; Piano, Ilaria; Manera, Clementina; Saccomanni, Giuseppe; Gargini, Claudia; Rapposelli, Simona | |
| Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease | 1-gen-2017 | Chen, Ziwei; Digiacomo, Maria; Tu, Yalin; Gu, Qiong; Wang, Shengnan; Yang, Xiaohong; Chu, Jiaqi; Chen, Qiuhe; Han, Yifan; Chen, Jingkao; Nesi, Giulia; Sestito, Simona; Macchia, Marco; Rapposelli, Simona; Pi, Rongbiao |