Human endogenous retroviruses-K/W seem play a role in fostering and exacerbation of some neurological diseases, including amyotrophic lateral sclerosis (ALS). Given these findings, we investigated the immunity response against HERV-K and HERV-W envelope surface (env-su) glycoprotein antigens in serum and cerebrospinal fluid (CSF) of ALS, multiple sclerosis (MS) and Alzheimer's disease (AD) patients, and in healthy controls (HCs).
Humoral immunity response to HERV-K/W differentiates between amyotrophic lateral sclerosis and other neurological diseases / Arru, Giannina; Mameli, Giuseppe; Deiana, Giovanni Andrea; Rassu, Anna Laura; Piredda, Rosanna; Sechi, Elia; Caggiu, Elisa; Bo, Marco; Nako, Enri; Urso, Daniele; Mariotto, Sara; Ferrari, Sergio; Zanusso, Gianluigi; Monaco, Salvatore; Sechi, Gianpietro; Sechi, Leonardo A. - In: EUROPEAN JOURNAL OF NEUROLOGY. - ISSN 1351-5101. - 25:8(2018), pp. 1076-1085. [10.1111/ene.13648]
Humoral immunity response to HERV-K/W differentiates between amyotrophic lateral sclerosis and other neurological diseases
Arru, Giannina;Deiana, Giovanni Andrea;Rassu, Anna Laura;Piredda, Rosanna;Sechi, Elia;Caggiu, Elisa;Bo, Marco;NAKO, Enri;Urso, Daniele;Sechi, GianPietro;Sechi, Leonardo A
2018-01-01
Abstract
Human endogenous retroviruses-K/W seem play a role in fostering and exacerbation of some neurological diseases, including amyotrophic lateral sclerosis (ALS). Given these findings, we investigated the immunity response against HERV-K and HERV-W envelope surface (env-su) glycoprotein antigens in serum and cerebrospinal fluid (CSF) of ALS, multiple sclerosis (MS) and Alzheimer's disease (AD) patients, and in healthy controls (HCs).| File | Dimensione | Formato | |
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