Human endogenous retroviruses-K/W seem play a role in fostering and exacerbation of some neurological diseases, including amyotrophic lateral sclerosis (ALS). Given these findings, we investigated the immunity response against HERV-K and HERV-W envelope surface (env-su) glycoprotein antigens in serum and cerebrospinal fluid (CSF) of ALS, multiple sclerosis (MS) and Alzheimer's disease (AD) patients, and in healthy controls (HCs).

Humoral immunity response to HERV-K/W differentiates between amyotrophic lateral sclerosis and other neurological diseases / Arru, Giannina; Mameli, Giuseppe; Deiana, Giovanni Andrea; Rassu, Anna Laura; Piredda, Rosanna; Sechi, Elia; Caggiu, Elisa; Bo, Marco; Nako, Enri; Urso, Daniele; Mariotto, Sara; Ferrari, Sergio; Zanusso, Gianluigi; Monaco, Salvatore; Sechi, Gianpietro; Sechi, Leonardo A. - In: EUROPEAN JOURNAL OF NEUROLOGY. - ISSN 1351-5101. - 25:8(2018), pp. 1076-1085. [10.1111/ene.13648]

Humoral immunity response to HERV-K/W differentiates between amyotrophic lateral sclerosis and other neurological diseases

Arru, Giannina;Deiana, Giovanni Andrea;Rassu, Anna Laura;Piredda, Rosanna;Sechi, Elia;Caggiu, Elisa;Bo, Marco;NAKO, Enri;Urso, Daniele;Sechi, GianPietro;Sechi, Leonardo A
2018

Abstract

Human endogenous retroviruses-K/W seem play a role in fostering and exacerbation of some neurological diseases, including amyotrophic lateral sclerosis (ALS). Given these findings, we investigated the immunity response against HERV-K and HERV-W envelope surface (env-su) glycoprotein antigens in serum and cerebrospinal fluid (CSF) of ALS, multiple sclerosis (MS) and Alzheimer's disease (AD) patients, and in healthy controls (HCs).
Humoral immunity response to HERV-K/W differentiates between amyotrophic lateral sclerosis and other neurological diseases / Arru, Giannina; Mameli, Giuseppe; Deiana, Giovanni Andrea; Rassu, Anna Laura; Piredda, Rosanna; Sechi, Elia; Caggiu, Elisa; Bo, Marco; Nako, Enri; Urso, Daniele; Mariotto, Sara; Ferrari, Sergio; Zanusso, Gianluigi; Monaco, Salvatore; Sechi, Gianpietro; Sechi, Leonardo A. - In: EUROPEAN JOURNAL OF NEUROLOGY. - ISSN 1351-5101. - 25:8(2018), pp. 1076-1085. [10.1111/ene.13648]
File in questo prodotto:
File Dimensione Formato  
Arru et al Europ journ of neurol.pdf

accesso aperto

Tipologia: Documento in Post-print (versione referata ma senza layout editoriale)
Licenza: DRM non definito
Dimensione 1.37 MB
Formato Adobe PDF
1.37 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11388/205521
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 23
  • ???jsp.display-item.citation.isi??? 24
social impact