The clinical history of patients with myelodysplastic syndromes (MDS) is characterised by bone marrow insufficiency as well as by the possible evolution into acute leukaemia. However a number of reports highlight the frequent occurrence of autoimmune manifestations involving different sites and organs. The present review will first describe the clinical pictures most often observed in MDS patients. The actual burden of autoimmunity will be then addressed by focusing on the few available registry studies. Finally, the potential collateral impact of specific treatments for MDS on the evolution of autoimmune disorders will be considered.

The burden of autoimmunity in myelodysplastic syndromes / Fozza, Claudio. - In: HEMATOLOGICAL ONCOLOGY. - ISSN 0278-0232. - (2017). [10.1002/hon.2423]

The burden of autoimmunity in myelodysplastic syndromes

FOZZA, Claudio
2017

Abstract

The clinical history of patients with myelodysplastic syndromes (MDS) is characterised by bone marrow insufficiency as well as by the possible evolution into acute leukaemia. However a number of reports highlight the frequent occurrence of autoimmune manifestations involving different sites and organs. The present review will first describe the clinical pictures most often observed in MDS patients. The actual burden of autoimmunity will be then addressed by focusing on the few available registry studies. Finally, the potential collateral impact of specific treatments for MDS on the evolution of autoimmune disorders will be considered.
The burden of autoimmunity in myelodysplastic syndromes / Fozza, Claudio. - In: HEMATOLOGICAL ONCOLOGY. - ISSN 0278-0232. - (2017). [10.1002/hon.2423]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/175593
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