In a 61-year-old man with glucose-6-phosphate dehydrogenase (G6PD) deficiency and poorly controlled non-insulin-dependent; diabetes mellitus, an episode of acute haemolysis occurred after the administration of glyburide (glibenclamide). Erythrocyte fragmentation, with haemoglobin condensation zones next to clear zones, was observed on peripheral blood smears. Since autoimmune haemolysis was excluded on the basis of laboratory data, acute haemolysis was ascribed to G6PD deficiency.
Glyburide-induced acute haemolysis in a G6PD-deficient patient with NIDDM / Meloni, Gianfranco; Meloni, T.. - In: BRITISH JOURNAL OF HAEMATOLOGY. - ISSN 0007-1048. - 92:1(1996), pp. 159-160. [10.1046/j.1365-2141.1996.275810.x]
Glyburide-induced acute haemolysis in a G6PD-deficient patient with NIDDM
MELONI, Gianfranco;
1996-01-01
Abstract
In a 61-year-old man with glucose-6-phosphate dehydrogenase (G6PD) deficiency and poorly controlled non-insulin-dependent; diabetes mellitus, an episode of acute haemolysis occurred after the administration of glyburide (glibenclamide). Erythrocyte fragmentation, with haemoglobin condensation zones next to clear zones, was observed on peripheral blood smears. Since autoimmune haemolysis was excluded on the basis of laboratory data, acute haemolysis was ascribed to G6PD deficiency.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
