The effect of clonidine on stress-induced cortisol secretion was studied in 10 patients undergoing general anesthesia for surgery; six other patients served as a control group and none of them was given clonidine. Central and peripheral alpha 2 stimulation by clonidine (average dose:0.45 mg over 60 minutes) was able to completely suppress cortisol release during surgery.
Effect of clonidine on stress-induced cortisol release in man during surgery / Masala, Antonio Giovanni Emilio; Satta, G; Alagna, S; Anania, Vittorio Domenico; Frassetto, Ga; Rovasio, Pp; Semiani, A.. - In: PHARMACOLOGICAL RESEARCH COMMUNICATIONS. - ISSN 0031-6989. - (1985), pp. 293-298.
Effect of clonidine on stress-induced cortisol release in man during surgery
MASALA, Antonio Giovanni Emilio;ANANIA, Vittorio Domenico;
1985-01-01
Abstract
The effect of clonidine on stress-induced cortisol secretion was studied in 10 patients undergoing general anesthesia for surgery; six other patients served as a control group and none of them was given clonidine. Central and peripheral alpha 2 stimulation by clonidine (average dose:0.45 mg over 60 minutes) was able to completely suppress cortisol release during surgery.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
