We studied a patient affected with idiopathic Parkinson's disease and levodopa-induced dyskinesias. Fatal hyperpyrexia followed simultaneous levodopa withdrawal and a decrease in the dosage of diphenhydramine. The clinical features were those of the neuroleptic malignant syndrome. The rapid decrease in dopaminergic activity may have been important in causing the syndrome.
Fatal hyperpyrexia after withdrawal of levodopa / Sechi, Gianpietro; Tanda, Francesco; Mutani, R.. - In: NEUROLOGY. - ISSN 0028-3878. - 34:2(1984), pp. 249-251.
Fatal hyperpyrexia after withdrawal of levodopa
SECHI, Gianpietro;TANDA, Francesco;
1984-01-01
Abstract
We studied a patient affected with idiopathic Parkinson's disease and levodopa-induced dyskinesias. Fatal hyperpyrexia followed simultaneous levodopa withdrawal and a decrease in the dosage of diphenhydramine. The clinical features were those of the neuroleptic malignant syndrome. The rapid decrease in dopaminergic activity may have been important in causing the syndrome.File in questo prodotto:
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