Here we present a dataset generated using formalin-fixed paraffin-embedded archival samples from two rare lung neuroendocrine tumor subtypes (namely, two atypical carcinoids, ACs, and two large-cell neuroendocrine carcinomas, LCNECs). Samples were subjected to a shotgun proteomics pipeline, comprising full-length protein extraction, SDS removal through spin columns, in solution trypsin digestion, long gradient liquid chromatography peptide separation and LTQ-Orbitrap mass spectrometry analysis. A total of 1260 and 2436 proteins were identified in the AC and LCNEC samples, respectively, with FDR <1%. MS data are available in the PeptideAtlas repository at http://www.peptideatlas.org/PASS/PASS00375.
Atypical carcinoid and large cell neuroendocrine carcinoma of the lung: a proteomic dataset from formalin-fixed archival samples / Tanca, A; Addis, Maria Filippa; Pisanu, Salvatore; Abbondio, Marcello; Pagnozzi, D; Eccher, A; Rindi, G; COSSU ROCCA, Paolo Alessandro; Uzzau, Sergio; Fanciulli, Giuseppe. - In: DATA IN BRIEF. - ISSN 2352-3409. - 7:(2016), pp. 529-531. [10.1016/j.dib.2016.02.083]