The geographical distribution of 49 mtDNA sequences from 22 localities in Southern Tuscany, Italy, was studied by molecular analysis of variance, by a new spatial autocorrelation statistic specifically designed for sequence data and by reconstructing genealogies of haplotypes. All these methods indicated a high homogeneity of populations. Nevertheless, genetic variability showed significant departure from equilibrium expectations, in agreement with the predicted effects of a population expansion. We suggest that a past population expansion that was probably associated with a migrational wave and with local gene flow between localities prevented spatial structuring in Southern Tuscany.
Geographic homogeneity and non-equilibrium patterns of mtDNA sequences in Tuscany, Italy / Bertorelle, G; Calafell, F; Francalacci, Paolo; Bertranpetit, J; Barbujani, G.. - In: HUMAN GENETICS. - ISSN 0340-6717. - 98:2(1996), pp. 145-150. [10.1007/s004390050178]
Geographic homogeneity and non-equilibrium patterns of mtDNA sequences in Tuscany, Italy
FRANCALACCI, Paolo;
1996-01-01
Abstract
The geographical distribution of 49 mtDNA sequences from 22 localities in Southern Tuscany, Italy, was studied by molecular analysis of variance, by a new spatial autocorrelation statistic specifically designed for sequence data and by reconstructing genealogies of haplotypes. All these methods indicated a high homogeneity of populations. Nevertheless, genetic variability showed significant departure from equilibrium expectations, in agreement with the predicted effects of a population expansion. We suggest that a past population expansion that was probably associated with a migrational wave and with local gene flow between localities prevented spatial structuring in Southern Tuscany.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
