we have described the isolation of the first CNN pincer osmium complexes [OsX(CNN)P2] to display high catalytic activity and productivity in the reduction of ketones by either TH or HY (TOFand TON up to 106 h1 and 105, respectively). A high enantioselectivity (up to 98% ee) is possible in both reactions with a remarkably low catalyst loading (0.005–0.002 mol%). To the best of our knowledge, this is the first example of an osmium complex that catalyzes the asymmetric HY of ketones. Evidence for an Os-OR vs. Os-H equilibrium suggests that both these species are involved in the catalytic pathways.
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|Titolo:||Osmium(II) CNN Pincer Complexes as Efficient Catalysts for both Asymmetric Transfer and H2 Hydrogenation of Ketones|
|Data di pubblicazione:||2008|
|Appare nelle tipologie:||1.1 Articolo in rivista|