A fatality due to the ingestion of solution containing phenol and o-cresol is described.The pathological findings were typical of acute substantial poisoning. Blood, urine and stomach content were obtained during post mortem examinations. Phenol and o-cresol were identified using GC/MS.The extractions from autopsy materials were obtained as follows: by gel permeation with cyclohexane/dichloromethane from stomach content, by solid phase extraction (SPE) from urine and by deproteinization with acetonitrile from blood. The phenol ando-cresol concentrations inthe samples werefound, respectively, asfollows: 115.0and 5.0mg/g in the stomach contents, 58.3 and 1.9mg/ml in the blood, 3.3 and 20.5mg/ml in the urine. Distributions of phenol in fatal poisonings havebeenreported[J.ForensicSci.27(1982)729;ForensicSci.Int.19(1982)177], but,usually, colorimetry was used as the analytical method and it cannot exclude the interference ofotherphenolic compounds.
Determination of phenol and o-cresol by GC/MS in a fatal poisoning case / Boatto, Gianpiero; Nieddu, M; Carta, Antonio; Pau, Amedeo; Lorenzoni, S; Manconi, P; Serra, D.. - In: FORENSIC SCIENCE INTERNATIONAL. - ISSN 0379-0738. - 139:2 −3(2004), pp. 191-194. [10.1016/j.forsciint.2003.10.023]
Determination of phenol and o-cresol by GC/MS in a fatal poisoning case
BOATTO, Gianpiero;CARTA, Antonio;PAU, Amedeo;
2004
Abstract
A fatality due to the ingestion of solution containing phenol and o-cresol is described.The pathological findings were typical of acute substantial poisoning. Blood, urine and stomach content were obtained during post mortem examinations. Phenol and o-cresol were identified using GC/MS.The extractions from autopsy materials were obtained as follows: by gel permeation with cyclohexane/dichloromethane from stomach content, by solid phase extraction (SPE) from urine and by deproteinization with acetonitrile from blood. The phenol ando-cresol concentrations inthe samples werefound, respectively, asfollows: 115.0and 5.0mg/g in the stomach contents, 58.3 and 1.9mg/ml in the blood, 3.3 and 20.5mg/ml in the urine. Distributions of phenol in fatal poisonings havebeenreported[J.ForensicSci.27(1982)729;ForensicSci.Int.19(1982)177], but,usually, colorimetry was used as the analytical method and it cannot exclude the interference ofotherphenolic compounds.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
