Amperometric polymer/enzyme composite (PEC) biosensors, incorporating a poly(o-phenylenediamine) ultra-thin permselective barrier, possess a variety of characteristics that make them suitable for monitoring brain energy and neurotransmitter dynamics in vivo. This review highlights PEC sensitivity and selectivity parameters, which allow development of the basic design in a systematic way in order to improve their performance and to diversify the analyte range of these novel probes of brain function
Designing sensitive and selective polymer/enzyme composite biosensors for brain monitoring in vivo / Oneill, R; Rocchitta, Gaia Giovanna Maria; Mcmahon, Cp; Serra, Pier Andrea; Lowry, J. P.. - In: TRAC. TRENDS IN ANALYTICAL CHEMISTRY. - ISSN 0165-9936. - 1:(2008), pp. 78-88.
Designing sensitive and selective polymer/enzyme composite biosensors for brain monitoring in vivo
ROCCHITTA, Gaia Giovanna Maria;SERRA, Pier Andrea;
2008-01-01
Abstract
Amperometric polymer/enzyme composite (PEC) biosensors, incorporating a poly(o-phenylenediamine) ultra-thin permselective barrier, possess a variety of characteristics that make them suitable for monitoring brain energy and neurotransmitter dynamics in vivo. This review highlights PEC sensitivity and selectivity parameters, which allow development of the basic design in a systematic way in order to improve their performance and to diversify the analyte range of these novel probes of brain functionI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
