The interactions between a few representative gold-based drugs and hen egg white lysozyme were studied by X-ray crystallography. High resolution crystal structures solved for three metallodrug–protein adducts provide valuable insight into the molecular mechanism of these promising metal compounds and the inherent protein metalation processes.
The mode of action of anticancer gold-based drugs: a structural perspective / Messori, L; Scaletti, F; Massai, L; Cinellu, Maria Agostina; Gabbiani, C; Vergara, A; Merlino, A.. - In: CHEMICAL COMMUNICATIONS. - ISSN 1359-7345. - 49:(2013), pp. 10100-10102.
The mode of action of anticancer gold-based drugs: a structural perspective.
CINELLU, Maria Agostina;
2013-01-01
Abstract
The interactions between a few representative gold-based drugs and hen egg white lysozyme were studied by X-ray crystallography. High resolution crystal structures solved for three metallodrug–protein adducts provide valuable insight into the molecular mechanism of these promising metal compounds and the inherent protein metalation processes.File in questo prodotto:
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