Purpose: To discuss the possible physiopathologic conditions responsible for these uncommon MR findings on the basis of our experience and a review of literature. Methods and Materials: In 6 patients, who underwent CT and MR examinations were incidentally detected focal nonhemorrhagic lesions of the splenium of the corpus callosum. They were suspected for encephalitis (2), dural sinus thrombosis(1), Multiple Sclerosis(3). MR examinations have been repeated after 4-8 and 12 weeks and in two cases after 6 and 9 months also. MRI and medical records were reviewed retrospectively with respect to the patients' clinical history, medication and laboratory findings to define the etiology of the lesions. Results: In all patients the detected lesions revealed to be isolated, with no contrast enhancement and reversible. In 4 patients the lesion disappeared after complete recovery of the underlying desease while in 2 patients the lesions persisted until to 6 and 9 months. Conclusion: To our knowledge and according to other authors experiences, being these lesions detected in a relatively wide number of conditions with heterogeneous etiopathogenetic factors, it leads to suppose a common underlying physiopatologic mechanism, that considering signal characteristic, reversibility and white matter location, could be represented by vasogenic edema.
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|Titolo:||Transient focal lesion in the splenium of the corpus callosum: MR imaging with an attempt to clinical - physiopathological explanation and review of the literature Le lesioni focali transitorie dello splenio del corpo calloso: imaging RM ed ipotesi eziopatogenetiche|
|Data di pubblicazione:||2007|
|Appare nelle tipologie:||1.1 Articolo in rivista|