A series of variously substituted quinoxalin-3-ones bearing an ethoxycarbonyl or carboxy group in the C-2 position has been prepared and their structures proved by 1H NMR spectroscopy. The obtained compounds were investigated in vitro for antimicrobial and anticancer activities. Preliminary results showed a moderate activity against a few strains of bacteria but no significant anticancer and anti-HIV activity.

Synthesis of substituted 2-ethoxycarbonyl- and 2-carboxyquinoxalin-3- ones for evaluation of antimicrobial and anticancer activity / Sanna, P; Carta, Antonio; Loriga, M; Zanetti, S; Sechi, Leonardo Antonio. - In: IL FARMACO. - ISSN 0014-827X. - 53:(1998), pp. 455-461.

Synthesis of substituted 2-ethoxycarbonyl- and 2-carboxyquinoxalin-3- ones for evaluation of antimicrobial and anticancer activity

CARTA, Antonio;SECHI, Leonardo Antonio
1998-01-01

Abstract

A series of variously substituted quinoxalin-3-ones bearing an ethoxycarbonyl or carboxy group in the C-2 position has been prepared and their structures proved by 1H NMR spectroscopy. The obtained compounds were investigated in vitro for antimicrobial and anticancer activities. Preliminary results showed a moderate activity against a few strains of bacteria but no significant anticancer and anti-HIV activity.
1998
Synthesis of substituted 2-ethoxycarbonyl- and 2-carboxyquinoxalin-3- ones for evaluation of antimicrobial and anticancer activity / Sanna, P; Carta, Antonio; Loriga, M; Zanetti, S; Sechi, Leonardo Antonio. - In: IL FARMACO. - ISSN 0014-827X. - 53:(1998), pp. 455-461.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/47948
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 50
  • ???jsp.display-item.citation.isi??? 46
social impact