A series of variously substituted quinoxalin-3-ones bearing an ethoxycarbonyl or carboxy group in the C-2 position has been prepared and their structures proved by 1H NMR spectroscopy. The obtained compounds were investigated in vitro for antimicrobial and anticancer activities. Preliminary results showed a moderate activity against a few strains of bacteria but no significant anticancer and anti-HIV activity.
Synthesis of substituted 2-ethoxycarbonyl- and 2-carboxyquinoxalin-3- ones for evaluation of antimicrobial and anticancer activity / Sanna, P; Carta, Antonio; Loriga, M; Zanetti, S; Sechi, Leonardo Antonio. - In: IL FARMACO. - ISSN 0014-827X. - 53:(1998), pp. 455-461.
Synthesis of substituted 2-ethoxycarbonyl- and 2-carboxyquinoxalin-3- ones for evaluation of antimicrobial and anticancer activity
CARTA, Antonio;SECHI, Leonardo Antonio
1998-01-01
Abstract
A series of variously substituted quinoxalin-3-ones bearing an ethoxycarbonyl or carboxy group in the C-2 position has been prepared and their structures proved by 1H NMR spectroscopy. The obtained compounds were investigated in vitro for antimicrobial and anticancer activities. Preliminary results showed a moderate activity against a few strains of bacteria but no significant anticancer and anti-HIV activity.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
