A genetic perspective of human history in Europe was derived from 22 binary markers of the nonrecombining Y chromosome (NRY). Ten lineages account for >95% of the 1007 European Y chromosomes studied. Geographic distribution and age estimates of alleles are compatible with two Paleolithic and one Neolithic migratory episode that have contributed to the modern European gene pool. A significant correlation between the NRY haplotype data and principal components based on 95 protein markers was observed, indicating the effectiveness of NRY binary polymorphisms in the characterization of human population composition and history.

The genetic legacy of paleolithic Homo sapiens sapiens in extant Europeans: A Y chromosome perspective / Semino, O; Passarino, G; Oefner, Pj; Lin, Aa; Arbuzova, S; Beckman, Le; De Benedictis, G; Francalacci, Paolo; Kouvatsi, A; Limborska, S; Marcikiae, M; Mika, A; Mika, B; Primorac, D; Santachiara Benerecetti, As; Cavalli Sforza, Ll; Underhill, Pa. - In: SCIENCE. - ISSN 0036-8075. - 290:5494(2000), pp. 1155-1159. [10.1126/science.290.5494.1155]

The genetic legacy of paleolithic Homo sapiens sapiens in extant Europeans: A Y chromosome perspective

FRANCALACCI, Paolo;
2000-01-01

Abstract

A genetic perspective of human history in Europe was derived from 22 binary markers of the nonrecombining Y chromosome (NRY). Ten lineages account for >95% of the 1007 European Y chromosomes studied. Geographic distribution and age estimates of alleles are compatible with two Paleolithic and one Neolithic migratory episode that have contributed to the modern European gene pool. A significant correlation between the NRY haplotype data and principal components based on 95 protein markers was observed, indicating the effectiveness of NRY binary polymorphisms in the characterization of human population composition and history.
2000
The genetic legacy of paleolithic Homo sapiens sapiens in extant Europeans: A Y chromosome perspective / Semino, O; Passarino, G; Oefner, Pj; Lin, Aa; Arbuzova, S; Beckman, Le; De Benedictis, G; Francalacci, Paolo; Kouvatsi, A; Limborska, S; Marcikiae, M; Mika, A; Mika, B; Primorac, D; Santachiara Benerecetti, As; Cavalli Sforza, Ll; Underhill, Pa. - In: SCIENCE. - ISSN 0036-8075. - 290:5494(2000), pp. 1155-1159. [10.1126/science.290.5494.1155]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/47260
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 649
  • ???jsp.display-item.citation.isi??? 607
social impact