In recent years, a number of newer designer drugs have entered the illicit drug market. The methylenedioxy-derivates of amphetamine represent the largest group of designer drugs. This paper describes a method for screening for and quantification of ten 2,5-methylenedioxyderivates of amphetamine and phenylethylamine in human urine, using capillary electrophoresis coupled to electrospray ionisation–mass spectrometry(CE–ESI–MS).PriortoCE–MSanalysis,asimplesolid-phaseextraction(SPE)wasusedforsamplecleanup.Themethodwas validates according to international guidelines.

Determination amphetamine-derived designer drugs in human urine by SPE extraction and capillary electrophoresis with mass spectrometry detection / Boatto, Gianpiero; Nieddu, M; Carta, Antonio; Pau, ; Palomba, M; Asproni, Battistina; Cerri, R.. - In: JOURNAL OF CHROMATOGRAPHY. B. - ISSN 1570-0232. - 814:1(2005), pp. 93-98. [10.1016/j.jchromb.2004.10.010]

Determination amphetamine-derived designer drugs in human urine by SPE extraction and capillary electrophoresis with mass spectrometry detection

BOATTO, Gianpiero;CARTA, Antonio;PALOMBA M;ASPRONI, Battistina;
2005

Abstract

In recent years, a number of newer designer drugs have entered the illicit drug market. The methylenedioxy-derivates of amphetamine represent the largest group of designer drugs. This paper describes a method for screening for and quantification of ten 2,5-methylenedioxyderivates of amphetamine and phenylethylamine in human urine, using capillary electrophoresis coupled to electrospray ionisation–mass spectrometry(CE–ESI–MS).PriortoCE–MSanalysis,asimplesolid-phaseextraction(SPE)wasusedforsamplecleanup.Themethodwas validates according to international guidelines.
Determination amphetamine-derived designer drugs in human urine by SPE extraction and capillary electrophoresis with mass spectrometry detection / Boatto, Gianpiero; Nieddu, M; Carta, Antonio; Pau, ; Palomba, M; Asproni, Battistina; Cerri, R.. - In: JOURNAL OF CHROMATOGRAPHY. B. - ISSN 1570-0232. - 814:1(2005), pp. 93-98. [10.1016/j.jchromb.2004.10.010]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/44715
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