The interaction of [VIVO(acac)2], acac = acetylacetonato, with H-chain ferritin has been studied. After dissociation and partial oxidation, [VIVO(acac)2] forms a mixed-valence [V15O36(Cl)]6− ion, which non-covalently binds with the protein nanocage. This polyoxidovanadate is formed at alkaline pH, showing that proteins can favor the formation and stabilization of species hardly isolable in solution.
Spherical mixed-valence pentadecavanadate binding to human H-chain ferritin / Lucignano, Rosanna; Tito, Gabriella; Ferraro, Giarita; Picone, Delia; Pisanu, Federico; Garribba, Eugenio; Merlino, Antonello. - In: INORGANIC CHEMISTRY FRONTIERS. - ISSN 2052-1553. - 12:21(2025), pp. 6870-6875. [10.1039/d5qi01694k]
Spherical mixed-valence pentadecavanadate binding to human H-chain ferritin
Pisanu, Federico;Garribba, Eugenio;Merlino, Antonello
2025-01-01
Abstract
The interaction of [VIVO(acac)2], acac = acetylacetonato, with H-chain ferritin has been studied. After dissociation and partial oxidation, [VIVO(acac)2] forms a mixed-valence [V15O36(Cl)]6− ion, which non-covalently binds with the protein nanocage. This polyoxidovanadate is formed at alkaline pH, showing that proteins can favor the formation and stabilization of species hardly isolable in solution.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
