Age-related macular degeneration (AMD) is a leading cause of significant vision impairment in individuals aged 50 and older, primarily impacting central vision. This study seeks to investigate potential associations between periodontal disease and age-related maculopathy in the analyzed clinical case. A male subject of 66 years old, with age-related degenerative maculopathy and severe periodontal disease, was evaluated and treated. After an initial phase of non-surgical causal periodontal therapy, the periodontal indices were re-evaluated. In addition, the extraction of hopeless teeth replaced by dental implants was performed. A retinal topography was used to assess possible regression of the pathology, and proper anti-VEGF therapy was administered. The results showed a regression of periodontal disease and an improvement of the degenerative maculopathy. These preliminary results, even if encouraging, should be supported by larger prospective trials.

Periodontal Disease and Age-Related Maculopathy: A Case Report / Ceruso, Francesco Mattia; Leon, Stephany Gabriela Zambrano; Fiorillo, Luca; Cervino, Gabriele; Cicciù, Marco; Heboyan, Artak; Pernice, Francesco; Meloni, Silvio; Tallarico, Marco. - In: CLINICAL MEDICINE INSIGHTS. CASE REPORTS. - ISSN 1179-5476. - 18:(2025). [10.1177/11795476251333251]

Periodontal Disease and Age-Related Maculopathy: A Case Report

Meloni, Silvio;Tallarico, Marco
2025-01-01

Abstract

Age-related macular degeneration (AMD) is a leading cause of significant vision impairment in individuals aged 50 and older, primarily impacting central vision. This study seeks to investigate potential associations between periodontal disease and age-related maculopathy in the analyzed clinical case. A male subject of 66 years old, with age-related degenerative maculopathy and severe periodontal disease, was evaluated and treated. After an initial phase of non-surgical causal periodontal therapy, the periodontal indices were re-evaluated. In addition, the extraction of hopeless teeth replaced by dental implants was performed. A retinal topography was used to assess possible regression of the pathology, and proper anti-VEGF therapy was administered. The results showed a regression of periodontal disease and an improvement of the degenerative maculopathy. These preliminary results, even if encouraging, should be supported by larger prospective trials.
2025
Periodontal Disease and Age-Related Maculopathy: A Case Report / Ceruso, Francesco Mattia; Leon, Stephany Gabriela Zambrano; Fiorillo, Luca; Cervino, Gabriele; Cicciù, Marco; Heboyan, Artak; Pernice, Francesco; Meloni, Silvio; Tallarico, Marco. - In: CLINICAL MEDICINE INSIGHTS. CASE REPORTS. - ISSN 1179-5476. - 18:(2025). [10.1177/11795476251333251]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/368409
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