INTRODUCTION: the aim of this study was to analyze the currently available literature on the use of autologous serum (AS) eye drops for the management of ocular surface disorders. EVIDENCE ACQUISITION: MEDLINE/PubMed and ISI Web of Sciences searches were performed according to MOOSE guidelines. Studies were considered eligible if: 1) they reported on AS eye drops for the management of ocular surface disorders/diseases; and 2) had been published in peer-reviewed journals. EVIDENCE SYNTHESIS: Initially, 144 records were identified from databases. Of these, 66 were excluded after the first screening, because they were irrelevant for this systematic review. Seventy-eight reports on AS eye drops in ocular surface disorders were sought for retrieval. Seventy-eight reports were assessed for eligibility; 11 of them were excluded, because they contained insufficient information for the purpose of this study. In total, 67 (86%) of the 78 initially identi- fied studies, published between 1984 and 2024, met selection criteria and were finally included in the review. A great heterogeneity in the preparation methods of AS eye drops, their final concentration, and the frequency and duration of use exists in the published literature. CONCLUSIONS: Although AS-based eye drops may be beneficial in the management of ocular surface disorders, con- clusions are limited due to the absence of controlled trials.

Autologous serum eye drops in the management of ocular surface disorders: a systematic review / Pinna, Antonio; Serra, Rita; Sacchi, Matteo; Dore, Stefano. - In: MINERVA OPHTHALMOLOGY. - ISSN 2785-1265. - 66:3-4(2024), pp. 61-72. [10.23736/s2785-1265.24.01887-1]

Autologous serum eye drops in the management of ocular surface disorders: a systematic review

PINNA, Antonio
;
SERRA, Rita;SACCHI, Matteo;DORE, Stefano
2024-01-01

Abstract

INTRODUCTION: the aim of this study was to analyze the currently available literature on the use of autologous serum (AS) eye drops for the management of ocular surface disorders. EVIDENCE ACQUISITION: MEDLINE/PubMed and ISI Web of Sciences searches were performed according to MOOSE guidelines. Studies were considered eligible if: 1) they reported on AS eye drops for the management of ocular surface disorders/diseases; and 2) had been published in peer-reviewed journals. EVIDENCE SYNTHESIS: Initially, 144 records were identified from databases. Of these, 66 were excluded after the first screening, because they were irrelevant for this systematic review. Seventy-eight reports on AS eye drops in ocular surface disorders were sought for retrieval. Seventy-eight reports were assessed for eligibility; 11 of them were excluded, because they contained insufficient information for the purpose of this study. In total, 67 (86%) of the 78 initially identi- fied studies, published between 1984 and 2024, met selection criteria and were finally included in the review. A great heterogeneity in the preparation methods of AS eye drops, their final concentration, and the frequency and duration of use exists in the published literature. CONCLUSIONS: Although AS-based eye drops may be beneficial in the management of ocular surface disorders, con- clusions are limited due to the absence of controlled trials.
2024
Autologous serum eye drops in the management of ocular surface disorders: a systematic review / Pinna, Antonio; Serra, Rita; Sacchi, Matteo; Dore, Stefano. - In: MINERVA OPHTHALMOLOGY. - ISSN 2785-1265. - 66:3-4(2024), pp. 61-72. [10.23736/s2785-1265.24.01887-1]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/357109
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