Nasal carcinomas in dogs are locally invasive neoplasms with a low metastatic rate that pose significant treatment challenges due to their location and aggressiveness. This study evaluates the safety, feasibility, and therapeutic outcomes of computed tomography-guided radiofrequency ablation (CT-guided RFA) in 15 dogs diagnosed with nasal adenocarcinoma. All patients underwent staging and histopathological diagnosis before treatment. CT-guided RFA achieved a significant tumor volume reduction (82.8%) and improvement in clinical signs such as nasal discharge, epistaxis, and respiratory distress, without complications. Post-RFA CT examinations demonstrated a significant decrease in Hounsfield units and tumor volume. This study has shown that CT-guided RFA is an effective cytoreductive option for minimally invasive management of nasal adenocarcinomas in dogs, particularly when traditional therapies like radiation therapy or surgery are not feasible.
Computed Tomography-Guided Radiofrequency Ablation of Nasal Carcinomas in Dogs / Alférez, María Dolores; Corda, Andrea; de Blas, Ignacio; Gago, Lucas; Fernandes, Telmo; Rodríguez-Piza, Ignacio; Balañá, Beatriz; Pentcheva, Plamena; Caruncho, Javier; Barbero-Fernández, Alicia; Llinás, Jorge; Rivas, David; Escudero, Amaia; Gómez-Ochoa, Pablo. - In: ANIMALS. - ISSN 2076-2615. - 14:24(2024). [10.3390/ani14243682]
Computed Tomography-Guided Radiofrequency Ablation of Nasal Carcinomas in Dogs
Corda, Andrea
;Pentcheva, Plamena;
2024-01-01
Abstract
Nasal carcinomas in dogs are locally invasive neoplasms with a low metastatic rate that pose significant treatment challenges due to their location and aggressiveness. This study evaluates the safety, feasibility, and therapeutic outcomes of computed tomography-guided radiofrequency ablation (CT-guided RFA) in 15 dogs diagnosed with nasal adenocarcinoma. All patients underwent staging and histopathological diagnosis before treatment. CT-guided RFA achieved a significant tumor volume reduction (82.8%) and improvement in clinical signs such as nasal discharge, epistaxis, and respiratory distress, without complications. Post-RFA CT examinations demonstrated a significant decrease in Hounsfield units and tumor volume. This study has shown that CT-guided RFA is an effective cytoreductive option for minimally invasive management of nasal adenocarcinomas in dogs, particularly when traditional therapies like radiation therapy or surgery are not feasible.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
