Purpose: This review aimed to evaluate the significance of assessing radial peripheral capillary (RPC) network parameters by optical coherence tomography angiography (OCTA) in patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection confirmed by polymerase chain reaction. Methods: A literature search was conducted in the PubMed database to select high-quality reviews and original articles on the use of OCTA for visualizing the RPC network and calculating RPC parameters. Results: The study revealed that systemic hypoxia, hypercoagulable state, and inflammation affect the RPC network in patients with coronavirus disease 2019 (COVID-19). Reduced RPC parameters were observed early in the course of SARS-CoV-2 infection and after several months of follow-up. Additionally, there was a correlation between reduced RPC parameters and subsequent thinning of the retinal nerve fiber layer. Conclusions: The OCTA examination of the retina and optic disc should be considered in patients with a history of COVID-19 to assess the impact of systemic hypoxia and inflammation on ocular function. Follow-up assessment of these patients is also necessary to understand the potential consequences of ischemia affecting the optic nerve, retina, and choroid.

Characteristics of the radial peripapillary capillary network in patients with COVID-19 based on optical coherence tomography angiography: a literature review / Kal, Magdalena; Brzdęk, Michał; Karska-Basta, Izabella; Rzymski, Piotr; Pinna, Antonio; Zarębska-Michaluk, Dorota. - In: ADVANCES IN MEDICAL SCIENCES. - ISSN 1896-1126. - 69:2(2024). [10.1016/j.advms.2024.07.001]

Characteristics of the radial peripapillary capillary network in patients with COVID-19 based on optical coherence tomography angiography: a literature review

Pinna, Antonio;
2024-01-01

Abstract

Purpose: This review aimed to evaluate the significance of assessing radial peripheral capillary (RPC) network parameters by optical coherence tomography angiography (OCTA) in patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection confirmed by polymerase chain reaction. Methods: A literature search was conducted in the PubMed database to select high-quality reviews and original articles on the use of OCTA for visualizing the RPC network and calculating RPC parameters. Results: The study revealed that systemic hypoxia, hypercoagulable state, and inflammation affect the RPC network in patients with coronavirus disease 2019 (COVID-19). Reduced RPC parameters were observed early in the course of SARS-CoV-2 infection and after several months of follow-up. Additionally, there was a correlation between reduced RPC parameters and subsequent thinning of the retinal nerve fiber layer. Conclusions: The OCTA examination of the retina and optic disc should be considered in patients with a history of COVID-19 to assess the impact of systemic hypoxia and inflammation on ocular function. Follow-up assessment of these patients is also necessary to understand the potential consequences of ischemia affecting the optic nerve, retina, and choroid.
2024
Characteristics of the radial peripapillary capillary network in patients with COVID-19 based on optical coherence tomography angiography: a literature review / Kal, Magdalena; Brzdęk, Michał; Karska-Basta, Izabella; Rzymski, Piotr; Pinna, Antonio; Zarębska-Michaluk, Dorota. - In: ADVANCES IN MEDICAL SCIENCES. - ISSN 1896-1126. - 69:2(2024). [10.1016/j.advms.2024.07.001]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/336129
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