The chronic use of glaucoma medications could improve the development of an ocular comorbidity, the glaucoma therapy-related ocular surface disease. This could be related to the exposure of the conjunctiva to preservatives, but also active compounds such as prostaglandin analogues may improve the risk of ocular surface inflammation. Inflammation has a negative impact on tolerability and adherence to eyedrops and to the outcome of filtration surgery as well. A stratification of glaucoma patients based not only on visual field progression but also on glaucoma therapy-related ocular surface disease would be desirable for a strategic management. Early diagnosis, individualized treatment, and safe surgical management should be the hallmarks of glaucoma treatment. One of the main issues for the proper and successful management of patients is the right timing, effectiveness and safety for both medical and surgical treatment options leading to a precision medicine in glaucoma disease as the best modern treatment.

Ocular surface and glaucoma, a mutual relationship. Practical suggestions for classification and management / Figus, Michele; Sacchi, Matteo; Rossi, Gemma Caterina; Babighian, Silvia; Del Castillo, José Manuel Benitez; de Polo, Laura; Melchionda, Eugenio; Posarelli, Chiara. - In: EUROPEAN JOURNAL OF OPHTHALMOLOGY. - ISSN 1724-6016. - (2023). [10.1177/11206721231199157]

Ocular surface and glaucoma, a mutual relationship. Practical suggestions for classification and management

Sacchi, Matteo;
2023-01-01

Abstract

The chronic use of glaucoma medications could improve the development of an ocular comorbidity, the glaucoma therapy-related ocular surface disease. This could be related to the exposure of the conjunctiva to preservatives, but also active compounds such as prostaglandin analogues may improve the risk of ocular surface inflammation. Inflammation has a negative impact on tolerability and adherence to eyedrops and to the outcome of filtration surgery as well. A stratification of glaucoma patients based not only on visual field progression but also on glaucoma therapy-related ocular surface disease would be desirable for a strategic management. Early diagnosis, individualized treatment, and safe surgical management should be the hallmarks of glaucoma treatment. One of the main issues for the proper and successful management of patients is the right timing, effectiveness and safety for both medical and surgical treatment options leading to a precision medicine in glaucoma disease as the best modern treatment.
2023
Ocular surface and glaucoma, a mutual relationship. Practical suggestions for classification and management / Figus, Michele; Sacchi, Matteo; Rossi, Gemma Caterina; Babighian, Silvia; Del Castillo, José Manuel Benitez; de Polo, Laura; Melchionda, Eugenio; Posarelli, Chiara. - In: EUROPEAN JOURNAL OF OPHTHALMOLOGY. - ISSN 1724-6016. - (2023). [10.1177/11206721231199157]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/326856
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact