Purpose: The aim of the present study was to estimate the 1 year prevalence and recovery rate of self-reported chemosensory dysfunction in a series of subjects with previous mild-to-moderate symptomatic COVID-19. Methods: Prospective study based on the SNOT-22, item “sense of smell or taste” and additional outcomes. Results: 268/315 patients (85.1%) completing the survey at baseline also completed the follow-up interview. The 12 months prevalence of self-reported COVID-19 associated chemosensory dysfunction was 21.3% (95% CI 16.5–26.7%). Of the 187 patients who complained of COVID-19 associated chemosensory dysfunction at baseline, 130 (69.5%; 95% CI 62.4–76.0%) reported complete resolution of smell or taste impairment, 41 (21.9%) reported a decrease in the severity, and 16 (8.6%) reported the symptom was unchanged or worse 1 year after onset. The risk of persistence was higher for patients reporting a baseline SNOT-22 score ≥ 4 (OR = 3.32; 95% CI 1.32–8.36) as well as for those requiring ≥ 22 days for a negative swab (OR = 2.18; 95% CI 1.12–4.27). Conclusion: A substantial proportion of patients with previous mild-to-moderate symptomatic COVID-19 characterized by new onset of chemosensory dysfunction still complained on altered sense of smell or taste 1 year after the onset.

Self-reported smell and taste recovery in coronavirus disease 2019 patients: a one-year prospective study / Boscolo-Rizzo, P.; Guida, F.; Polesel, J.; Marcuzzo, A. V.; Antonucci, P.; Capriotti, V.; Sacchet, E.; Cragnolini, F.; D'Alessandro, A.; Zanelli, E.; Marzolino, R.; Lazzarin, C.; Tofanelli, M.; Gardenal, N.; Borsetto, D.; Hopkins, C.; Vaira, L. A.; Tirelli, G.. - In: EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY. - ISSN 0937-4477. - 279:1(2022), pp. 515-520. [10.1007/s00405-021-06839-w]

Self-reported smell and taste recovery in coronavirus disease 2019 patients: a one-year prospective study

Vaira L. A.;
2022-01-01

Abstract

Purpose: The aim of the present study was to estimate the 1 year prevalence and recovery rate of self-reported chemosensory dysfunction in a series of subjects with previous mild-to-moderate symptomatic COVID-19. Methods: Prospective study based on the SNOT-22, item “sense of smell or taste” and additional outcomes. Results: 268/315 patients (85.1%) completing the survey at baseline also completed the follow-up interview. The 12 months prevalence of self-reported COVID-19 associated chemosensory dysfunction was 21.3% (95% CI 16.5–26.7%). Of the 187 patients who complained of COVID-19 associated chemosensory dysfunction at baseline, 130 (69.5%; 95% CI 62.4–76.0%) reported complete resolution of smell or taste impairment, 41 (21.9%) reported a decrease in the severity, and 16 (8.6%) reported the symptom was unchanged or worse 1 year after onset. The risk of persistence was higher for patients reporting a baseline SNOT-22 score ≥ 4 (OR = 3.32; 95% CI 1.32–8.36) as well as for those requiring ≥ 22 days for a negative swab (OR = 2.18; 95% CI 1.12–4.27). Conclusion: A substantial proportion of patients with previous mild-to-moderate symptomatic COVID-19 characterized by new onset of chemosensory dysfunction still complained on altered sense of smell or taste 1 year after the onset.
2022
Self-reported smell and taste recovery in coronavirus disease 2019 patients: a one-year prospective study / Boscolo-Rizzo, P.; Guida, F.; Polesel, J.; Marcuzzo, A. V.; Antonucci, P.; Capriotti, V.; Sacchet, E.; Cragnolini, F.; D'Alessandro, A.; Zanelli, E.; Marzolino, R.; Lazzarin, C.; Tofanelli, M.; Gardenal, N.; Borsetto, D.; Hopkins, C.; Vaira, L. A.; Tirelli, G.. - In: EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY. - ISSN 0937-4477. - 279:1(2022), pp. 515-520. [10.1007/s00405-021-06839-w]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/313079
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