The incidence of cutaneous melanoma is increasing in Italy, in parallel with the implementation of gene panels. Therefore, a revision of national genetic assessment criteria for hereditary melanoma may be needed. The aim of this study was to identify predictors of susceptibility variants in the largest prospective cohort of Italian high-risk melanoma cases studied to date.
Predictors of germline status for hereditary melanoma: 5 years of multi-gene panel testing within the Italian Melanoma Intergroup / Bruno, W; Dalmasso, B; Barile, M; Andreotti, V; Elefanti, L; Colombino, M; Vanni, I; Allavena, E; Barbero, F; Passoni, E; Merelli, B; Pellegrini, S; Morgese, F; Danesi, R; Calò, V; Bazan, V; D'Elia, A V; Molica, C; Gensini, F; Sala, E; Uliana, V; Soma, P F; Genuardi, M; Ballestrero, A; Spagnolo, F; Tanda, E; Queirolo, P; Mandalà, M; Stanganelli, I; Palmieri, G; Menin, C; Pastorino, L; Ghiorzo, P. - In: ESMO OPEN. - ISSN 2059-7029. - 7:4(2022), p. 100525. [10.1016/j.esmoop.2022.100525]
Predictors of germline status for hereditary melanoma: 5 years of multi-gene panel testing within the Italian Melanoma Intergroup
Palmieri, GInvestigation
;
2022-01-01
Abstract
The incidence of cutaneous melanoma is increasing in Italy, in parallel with the implementation of gene panels. Therefore, a revision of national genetic assessment criteria for hereditary melanoma may be needed. The aim of this study was to identify predictors of susceptibility variants in the largest prospective cohort of Italian high-risk melanoma cases studied to date.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
