Crohn's disease, a human disease similar to paratuberculosis in animals is the most painful and devastating disease that may involve infection withM. aviumsubsp.paratuberculosis(MAP), different genetic polymorphisms and an immune dysregulation syndrome. Treatment of Crohn's disease is most commonly based on 5-aminosalicylic acid (5-ASA) compounds, corticosteroids, and immunosuppressive agents. Recently, biological therapies using monoclonal antibodies against inflammatory cytokines have shown some positive results. However, all these therapies treat the symptoms not the cause of the disease.

"In vitro" activities of antimycobacterial agents againstMycobacterium aviumsubsp.paratuberculosislinked to Crohn's disease and paratuberculosis / Sechi, Leonardo Antonio; Cannas, Sara; Ortu, Silvia; Ahmed, Niyaz; Molicotti, Paola; Zanetti, Stefania Anna Lucia. - In: ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS. - ISSN 1476-0711. - 5:27(2006), pp. 1-3. [10.1186/1476-0711-5-27]

"In vitro" activities of antimycobacterial agents againstMycobacterium aviumsubsp.paratuberculosislinked to Crohn's disease and paratuberculosis

Sechi, Leonardo Antonio;Cannas, Sara;Ortu, Silvia;Molicotti, Paola;Zanetti, Stefania Anna Lucia
2006

Abstract

Crohn's disease, a human disease similar to paratuberculosis in animals is the most painful and devastating disease that may involve infection withM. aviumsubsp.paratuberculosis(MAP), different genetic polymorphisms and an immune dysregulation syndrome. Treatment of Crohn's disease is most commonly based on 5-aminosalicylic acid (5-ASA) compounds, corticosteroids, and immunosuppressive agents. Recently, biological therapies using monoclonal antibodies against inflammatory cytokines have shown some positive results. However, all these therapies treat the symptoms not the cause of the disease.
"In vitro" activities of antimycobacterial agents againstMycobacterium aviumsubsp.paratuberculosislinked to Crohn's disease and paratuberculosis / Sechi, Leonardo Antonio; Cannas, Sara; Ortu, Silvia; Ahmed, Niyaz; Molicotti, Paola; Zanetti, Stefania Anna Lucia. - In: ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS. - ISSN 1476-0711. - 5:27(2006), pp. 1-3. [10.1186/1476-0711-5-27]
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11388/265105
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact