Isolation, characterization and pharmacological activity ofMagydaris pastinacea(Lam.) Paol.glucosides

The glycoside fraction of fresh rhizomes fromMagydaris pastinacea(Lam.) Paol. was separated from the alcoholic extract using the method of Kobayashiet al.The fraction was found to have six main constituents, the most abundant of which had previously been isolated and identified as 7-O-β-D-glucopyranosyl-8-(2',3'-dihydroxy-3-methyl-butylcoumarin). The present paper describes the separation and characterization of the other constituents, all with coumarin or furancoumarin structures. Pharmacological experiments to test these compounds as platelet antiaggregants are also reported.