In the search of new HIV-1 integrase (IN) inhibitors, we synthesized a series of multimeric 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives. Preliminary results indicate that hyperbranched architectures could represent a peculiar molecular requisite for the development of new antiviral lead compounds
Hyperbranched molecular structures with potential antiviral activity: derivatives of 5,6-dihydroxyindole-2-carboxylic acid / Sechi, Mario; Casu, Fabio; Campesi, Ilaria; Fiori, Stefano; Mariani, Alberto. - In: MOLECULES. - ISSN 1420-3049. - 11:12(2006), pp. 968-977. [10.3390/11120968]
Hyperbranched molecular structures with potential antiviral activity: derivatives of 5,6-dihydroxyindole-2-carboxylic acid
Sechi, Mario;Campesi, Ilaria;Fiori, Stefano;Mariani, Alberto
2006-01-01
Abstract
In the search of new HIV-1 integrase (IN) inhibitors, we synthesized a series of multimeric 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives. Preliminary results indicate that hyperbranched architectures could represent a peculiar molecular requisite for the development of new antiviral lead compoundsFile in questo prodotto:
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