Phytotoxic metabolites produced by Botryosphaeriaceae involved in grapevine trunk diseases

Fungi belonging to the Botryosphaeriaceae family are well known as cosmopolitan pathogens, saprophytes and endophytes and occur on a wide range of hosts including grapevine.More recently, a new species ofLasiodiplodiawas isolated from declining grapevines in Sardinia (Italy). This still undescribed species showed to produce in liquid culture several phytotoxic secondary metabolites. In this communication the chemical and biological characterization of these bioactive secondary metabolites is discussed together with their role in the pathogenesis process.