Pursuing our investigations on 7-amino-2,3-polymethyleneindole derivatives, a set of 7-(dimethylaminomethylene)-amino-2,3-polymethyleneindoles, together with some other aryl or cycloalkyl substituted formamidines, were prepared and tested for analgesic and antiinflammatory activities. Several compounds resulted endowed with one or both of these activities; the indole derivatives 1 and 2 exhibited a good degree of both of them.
Formamidines with antinociceptive and antiinflammatory activities / Boatto, Gianpiero; Pau, Amedeo; Cerri, Riccardo; Sparatore, Fabio; Carrara, Maria; Satta, Margherita; Cima, Lorenzo. - In: IL FARMACO. - ISSN 0014-827X. - 46:2(1991), pp. 369-378.
Formamidines with antinociceptive and antiinflammatory activities
Boatto, Gianpiero;Pau, Amedeo;Cerri, Riccardo;Satta, Margherita;
1991-01-01
Abstract
Pursuing our investigations on 7-amino-2,3-polymethyleneindole derivatives, a set of 7-(dimethylaminomethylene)-amino-2,3-polymethyleneindoles, together with some other aryl or cycloalkyl substituted formamidines, were prepared and tested for analgesic and antiinflammatory activities. Several compounds resulted endowed with one or both of these activities; the indole derivatives 1 and 2 exhibited a good degree of both of them.File | Dimensione | Formato | |
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