In primary squamous cell carcinoma of the larynx (LSCC), CaM2+ binding S100A2 protein underexpression was already found to be associated with poor tumour differentiation and shorter overall survival. In the present work, the role of S100A2 protein expression in the prediction of regional metastasis-free survival (MFS) was investigated to guide neck management in LSCC.

Diminished expression of S100A2, a putative tumour suppressor, is an independent predictive factor of neck node relapse in laryngeal squamous cell carcinoma / Almadori, G.; Bussu, F.; Gall, J.; Rigante, M.; Lauriola, L.; Michett, F.; Maggiano, N.; Schafer, B. W.; Heizmann, C. W.; Ranelletti, F. O.; Paludetti, G.. - In: JOURNAL OF OTOLARYNGOLOGY-HEAD AND NECK SURGERY. - ISSN 1916-0216. - 38:1(2009), pp. 16-22.

Diminished expression of S100A2, a putative tumour suppressor, is an independent predictive factor of neck node relapse in laryngeal squamous cell carcinoma

Bussu F.;
2009

Abstract

In primary squamous cell carcinoma of the larynx (LSCC), CaM2+ binding S100A2 protein underexpression was already found to be associated with poor tumour differentiation and shorter overall survival. In the present work, the role of S100A2 protein expression in the prediction of regional metastasis-free survival (MFS) was investigated to guide neck management in LSCC.
Diminished expression of S100A2, a putative tumour suppressor, is an independent predictive factor of neck node relapse in laryngeal squamous cell carcinoma / Almadori, G.; Bussu, F.; Gall, J.; Rigante, M.; Lauriola, L.; Michett, F.; Maggiano, N.; Schafer, B. W.; Heizmann, C. W.; Ranelletti, F. O.; Paludetti, G.. - In: JOURNAL OF OTOLARYNGOLOGY-HEAD AND NECK SURGERY. - ISSN 1916-0216. - 38:1(2009), pp. 16-22.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/245997
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