BACKGROUND: Benign paroxysmal positional vertigo (BPPV) has a reported recurrence ranging from 26.8 to 50%. Osteoporosis and Vitamin D deficiency seems to have an impact on recurrence of BPPV. OBJECTIVE: to evaluate the impact of osteoporosis and Vitamin D deficiency on recurrence of BPPV. METHODS: 73 consecutive patients were divided in two groups according to the presence (group 1) or absence (group 0) of a recurrent episode. BMD, femoral and lumbar T-scores and Vitamin D levels were recorded. Statistical analysis was performed to investigate correlations. RESULTS: patients in group 1 had statistically significant lower values of both femoral (-1,62±1,06 vs. -0,53±1,51; p = 0,001), lumbar T-score (-2,10±1,19 vs -0, 53±1.51, p = 0.001) and Vitamin D (19.53±15.33). The values of femoral T-score and Vitamin D could be combined in a model able to properly classify 65.8% of the cases (p = 0.002) as isolated or recurrent BPPV, with high accuracy (AUC 0.710 [0.590 -0.830]). CONCLUSION: present data show a probable correlation between osteoporosis and Vitamin D with recurrent BPPV.

Relationship between calcium metabolism and benign paroxysmal positional vertigo in north Sardinia population / Melis, A.; Rizzo, D.; Gallus, R.; Leo, M. E.; Turra, N.; Masnaghetti, D.; De Luca, L. M.; Piras, A.; Bussu, F.. - In: JOURNAL OF VESTIBULAR RESEARCH. - ISSN 0957-4271. - 30:6(2020), pp. 375-382. [10.3233/VES-200025]

Relationship between calcium metabolism and benign paroxysmal positional vertigo in north Sardinia population

Rizzo D.;Masnaghetti D.;Bussu F.
2020-01-01

Abstract

BACKGROUND: Benign paroxysmal positional vertigo (BPPV) has a reported recurrence ranging from 26.8 to 50%. Osteoporosis and Vitamin D deficiency seems to have an impact on recurrence of BPPV. OBJECTIVE: to evaluate the impact of osteoporosis and Vitamin D deficiency on recurrence of BPPV. METHODS: 73 consecutive patients were divided in two groups according to the presence (group 1) or absence (group 0) of a recurrent episode. BMD, femoral and lumbar T-scores and Vitamin D levels were recorded. Statistical analysis was performed to investigate correlations. RESULTS: patients in group 1 had statistically significant lower values of both femoral (-1,62±1,06 vs. -0,53±1,51; p = 0,001), lumbar T-score (-2,10±1,19 vs -0, 53±1.51, p = 0.001) and Vitamin D (19.53±15.33). The values of femoral T-score and Vitamin D could be combined in a model able to properly classify 65.8% of the cases (p = 0.002) as isolated or recurrent BPPV, with high accuracy (AUC 0.710 [0.590 -0.830]). CONCLUSION: present data show a probable correlation between osteoporosis and Vitamin D with recurrent BPPV.
2020
Relationship between calcium metabolism and benign paroxysmal positional vertigo in north Sardinia population / Melis, A.; Rizzo, D.; Gallus, R.; Leo, M. E.; Turra, N.; Masnaghetti, D.; De Luca, L. M.; Piras, A.; Bussu, F.. - In: JOURNAL OF VESTIBULAR RESEARCH. - ISSN 0957-4271. - 30:6(2020), pp. 375-382. [10.3233/VES-200025]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/241389
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