The neurophysiological hallmark of REM sleep behavior disorder (RBD) is loss of atonia during REM sleep. Indeed, signs and symptoms of neurodegeneration can occur after years, even decades, from its beginning. This study aimed to measure neurophysiological alterations of the brainstem that potentially correlate with the severity of atonia loss, and determining whether a prodromal neurodegenerative disorder underlines this condition when it occurs as an isolated condition (iRBD).

REM Sleep without atonia correlates with abnormal vestibular-evoked myogenic potentials in isolated REM sleep behavior disorder / Puligheddu, Monica; Figorilli, Michela; Serra, Alessandra; Laccu, Ilaria; Congiu, Patrizia; Tamburrino, Ludovica; de Natale, Edoardo Rosario; Ginatempo, Francesca; Deriu, Franca; Loi, Gianluigi; Fantini, Maria Livia; Schenck, Carlos H; Ferri, Raffaele. - In: SLEEP. - ISSN 0161-8105. - July 16(2019), pp. 1-8. [10.1093/sleep/zsz128]

REM Sleep without atonia correlates with abnormal vestibular-evoked myogenic potentials in isolated REM sleep behavior disorder

Ginatempo, Francesca;Deriu, Franca;
2019-01-01

Abstract

The neurophysiological hallmark of REM sleep behavior disorder (RBD) is loss of atonia during REM sleep. Indeed, signs and symptoms of neurodegeneration can occur after years, even decades, from its beginning. This study aimed to measure neurophysiological alterations of the brainstem that potentially correlate with the severity of atonia loss, and determining whether a prodromal neurodegenerative disorder underlines this condition when it occurs as an isolated condition (iRBD).
2019
REM Sleep without atonia correlates with abnormal vestibular-evoked myogenic potentials in isolated REM sleep behavior disorder / Puligheddu, Monica; Figorilli, Michela; Serra, Alessandra; Laccu, Ilaria; Congiu, Patrizia; Tamburrino, Ludovica; de Natale, Edoardo Rosario; Ginatempo, Francesca; Deriu, Franca; Loi, Gianluigi; Fantini, Maria Livia; Schenck, Carlos H; Ferri, Raffaele. - In: SLEEP. - ISSN 0161-8105. - July 16(2019), pp. 1-8. [10.1093/sleep/zsz128]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/227153
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