Ischemia-Reperfusion (I/R) injury is the tissue damage that results from re-oxygenation of ischemic tissues. There are many players that contribute to I/R injury. One of these factors is the family of microRNAs (miRNAs), which are currently being heavily studied. This review aims to critically summarize the latest papers that attributed roles of certain miRNAs in I/R injury, particularly in diabetic conditions and dissect their potential as novel pharmacologic targets in the treatment and management of diabetes.
MicroRNAs as Potential Pharmaco-targets in Ischemia-Reperfusion Injury Compounded by Diabetes / Dehaini, Hassan; Awada, Hussein; El-Yazbi, Ahmed; Zouein, Fouad A; Issa, Khodr; Eid, Assaad A; Ibrahim, Maryam; Badran, Adnan; Baydoun, Elias; Pintus, Gianfranco; Eid, Ali H. - In: CELLS. - ISSN 2073-4409. - 8:2(2019), p. 152. [10.3390/cells8020152]
MicroRNAs as Potential Pharmaco-targets in Ischemia-Reperfusion Injury Compounded by Diabetes
Pintus, Gianfranco
Writing – Review & Editing
;
2019-01-01
Abstract
Ischemia-Reperfusion (I/R) injury is the tissue damage that results from re-oxygenation of ischemic tissues. There are many players that contribute to I/R injury. One of these factors is the family of microRNAs (miRNAs), which are currently being heavily studied. This review aims to critically summarize the latest papers that attributed roles of certain miRNAs in I/R injury, particularly in diabetic conditions and dissect their potential as novel pharmacologic targets in the treatment and management of diabetes.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.