In this paper, we introduce a novel parameter, called Cytogenetic Identity, to describe differences and similarities between genomes. Using Whole Comparative Genomic Hybridization plus Digital Image Analysis, we present a new methodology that employs the whole genome, including highly repeated DNA sequences, to provide a general picture about the differences between individuals of the same or different species. The proposed approach has a great potential in many different fields of research, like evolution, ecology, phylogenesis, etc. In the present study, we applied Cytogenetic Identity to establish a quantitative degree of divergence between different goat breeds. Advantages as well as disadvantages of the new parameter are discussed.
Cytogenetic identity: A new parameter for estimating whole-genome differences / Nieddu, Mariella; Robledo, Renato; Mezzanotte, Roberto; Vacca, Giuseppe Massimo; Pita, Miguel. - In: GENE REPORTS. - ISSN 2452-0144. - 11:(2018), pp. 235-238. [10.1016/j.genrep.2018.04.005]
Cytogenetic identity: A new parameter for estimating whole-genome differences
Vacca, Giuseppe Massimo;
2018-01-01
Abstract
In this paper, we introduce a novel parameter, called Cytogenetic Identity, to describe differences and similarities between genomes. Using Whole Comparative Genomic Hybridization plus Digital Image Analysis, we present a new methodology that employs the whole genome, including highly repeated DNA sequences, to provide a general picture about the differences between individuals of the same or different species. The proposed approach has a great potential in many different fields of research, like evolution, ecology, phylogenesis, etc. In the present study, we applied Cytogenetic Identity to establish a quantitative degree of divergence between different goat breeds. Advantages as well as disadvantages of the new parameter are discussed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.