Hepatitis C virus (HCV) treatment with Interferon (IFN)-free direct-acting antiviral agents (DAAs) showed high rates of success, leading to substantial changes in this field. However, limited data are available about the evolution of liver disease after HCV eradication. Recently, published studies on the recurrence of hepatocellular carcinoma (HCC) after HCV treatment raised questions on the real benefit of treatment of patients with advanced fibrosis or cirrhosis. We report a case of a 45-years-old cirrhotic patient successfully treated with DAAs who developed an HCC after HCV eradication.
HEPATOCELLULAR CARCINOMA DEVELOPMENT IN A PATIENT WITH HCV INFECTION AFTER ERADICATION WITH DIRECT-ACTING ANTIVIRAL AGENTS / Fiore, Vito; Vidili, Gianpaolo; Bagella, Paola; Lobrano, Gloria; Muredda, Alberto Augusto; Caruana, Giorgia; Babudieri, Sergio; Madeddu, Giordano. - In: WORLD CANCER RESEARCH JOURNAL. - ISSN 2372-3416. - 4:1(2017), p. 1.