A novel type of metal-free oxidative cross-coupling for the synthesis of symmetrical and mixed anhydrides from aldehydes or benzylic alcohols has been developed. The aldehydes or alcohols were converted in situ into their corresponding acyl chlorides, which were then reacted with an array of carboxylic acids. The methodology has a general applicability, and was successfully employed to prepare either aromatic or aliphatic symmetrical anhydrides and mixed anhydrides, which are very unstable compounds.
Anhydrides from aldehydes or alcohols via oxidative cross-coupling / Gaspa, Silvia; Amura, Ida; Porcheddu, Andrea; DE LUCA, Lidia Vera Giovanna. - In: NEW JOURNAL OF CHEMISTRY. - ISSN 1144-0546. - 41:3(2017), pp. 931-939. [10.1039/C6NJ02625G]
Anhydrides from aldehydes or alcohols via oxidative cross-coupling
Gaspa, Silvia;DE LUCA, Lidia Vera Giovanna
2017-01-01
Abstract
A novel type of metal-free oxidative cross-coupling for the synthesis of symmetrical and mixed anhydrides from aldehydes or benzylic alcohols has been developed. The aldehydes or alcohols were converted in situ into their corresponding acyl chlorides, which were then reacted with an array of carboxylic acids. The methodology has a general applicability, and was successfully employed to prepare either aromatic or aliphatic symmetrical anhydrides and mixed anhydrides, which are very unstable compounds.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
