A prototype of proton Computed Tomography (pCT) system for hadron-therapy has been manufactured and tested in a 175. MeV proton beam with a non-homogeneous phantom designed to simulate high-contrast material. BI-SART reconstruction algorithms have been implemented with GPU parallelism, taking into account of most likely paths of protons in matter. Reconstructed tomography images with density resolutions r.m.s. down to ~1% and spatial resolutions <1. mm, achieved within processing times of ~15' for a 512×512 pixels image prove that this technique will be beneficial if used instead of X-CT in hadron-therapy.

Proton computed tomography images with algebraic reconstruction / Bruzzi, M.; Civinini, C.; Scaringella, M.; Bonanno, D.; Brianzi, M.; Carpinelli, Massimo; Cirrone, G. A. P.; Cuttone, G.; Presti, D. Lo; Maccioni, G.; Pallotta, S.; Randazzo, N.; Romano, F.; Sipala, Valeria; Talamonti, C.; Vanzi, E.. - In: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT. - ISSN 0168-9002. - 845:(2017), pp. 652-655. [10.1016/j.nima.2016.05.056]

Proton computed tomography images with algebraic reconstruction

CARPINELLI, Massimo;SIPALA, Valeria;
2017-01-01

Abstract

A prototype of proton Computed Tomography (pCT) system for hadron-therapy has been manufactured and tested in a 175. MeV proton beam with a non-homogeneous phantom designed to simulate high-contrast material. BI-SART reconstruction algorithms have been implemented with GPU parallelism, taking into account of most likely paths of protons in matter. Reconstructed tomography images with density resolutions r.m.s. down to ~1% and spatial resolutions <1. mm, achieved within processing times of ~15' for a 512×512 pixels image prove that this technique will be beneficial if used instead of X-CT in hadron-therapy.
2017
Proton computed tomography images with algebraic reconstruction / Bruzzi, M.; Civinini, C.; Scaringella, M.; Bonanno, D.; Brianzi, M.; Carpinelli, Massimo; Cirrone, G. A. P.; Cuttone, G.; Presti, D. Lo; Maccioni, G.; Pallotta, S.; Randazzo, N.; Romano, F.; Sipala, Valeria; Talamonti, C.; Vanzi, E.. - In: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT. - ISSN 0168-9002. - 845:(2017), pp. 652-655. [10.1016/j.nima.2016.05.056]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11388/167470
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