"Visceral Leishmaniasis (VL) is a zoonotic disease caused by Leishmaniainfantum in the Mediterranean area. Dogs are the main reservoir of Leishmaniainf antum parasites. Disease management represents a serious problem, since anti-Leishmania drugs have limited efficacy in both symptomatic and asymptomatic dogs, which are infective to phlebotomine vectors. In many tropical and sub-tropical countries the development of a safe and easily-available vaccine has high priority. DNA vaccines represent one of the most recent innovations in the field of immunization."
Development and Clinical Trial of a Novel DNA Vaccine as Immunotherapy during Canine Leishmaniasis / Manna, L; Piras, Im; Ciprì, V; Alberti, Alberto; Peruta, Id; Del Pizzo, Cm; Gammarano, N; Coradduzza, E; Cacciotto, Carla; Pittau, Marco; Gravino, Ae; Chessa, Bernardo. - In: JOURNAL OF VACCINES & VACCINATION. - ISSN 2157-7560. - 3:6(2012). [10.4172/2157-7560.1000155]
Development and Clinical Trial of a Novel DNA Vaccine as Immunotherapy during Canine Leishmaniasis
ALBERTI, Alberto;CACCIOTTO, Carla;PITTAU, Marco;CHESSA, Bernardo
2012-01-01
Abstract
"Visceral Leishmaniasis (VL) is a zoonotic disease caused by Leishmaniainfantum in the Mediterranean area. Dogs are the main reservoir of Leishmaniainf antum parasites. Disease management represents a serious problem, since anti-Leishmania drugs have limited efficacy in both symptomatic and asymptomatic dogs, which are infective to phlebotomine vectors. In many tropical and sub-tropical countries the development of a safe and easily-available vaccine has high priority. DNA vaccines represent one of the most recent innovations in the field of immunization."I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
