One-hundred-and-four patients, 52 with diffuse psoriasis and 52 with skin unrelated to' metabolic defects were studied. The psoriatic patients had a high prevale ce of diabetes (21.2%), ishaemic heart disease (23.1%) and hypertension (36.5%).The lipid and uric acid metabolic defects in the psoriatics were no different from those found in controls.40% psoriasi patients had high plasmare in attività and urinari aldosterone levels.It suggest that psoriatic mcroangiopathy may be' responsabile for activating the renin -angitensin-aldosterone system and that this, in turn, may determinerà the hypertension.Since a high plasma renin attività is present in manu normotensive psoriasi patients, the microangipathy could be' due to' local or generalized arteriolar constriction induce by the hyperangiotensinaemia.

Psoriasi ed ipertensione arteriosa essenziale:evidenza di una aumentata attivita' del sistema renina-renina-aldosterone nei pazienti psoriasi / Madeddu, P; Ena, Pasquale; Glorioso, N; Cerimele, D.. - In: ANNALI ITALIANI DI DERMATOLOGIA CLINICA E SPERIMENTALE. - ISSN 0365-169X. - 36:4(1982), pp. 367-376.

Psoriasi ed ipertensione arteriosa essenziale:evidenza di una aumentata attivita' del sistema renina-renina-aldosterone nei pazienti psoriasi.

ENA, Pasquale;
1982

Abstract

One-hundred-and-four patients, 52 with diffuse psoriasis and 52 with skin unrelated to' metabolic defects were studied. The psoriatic patients had a high prevale ce of diabetes (21.2%), ishaemic heart disease (23.1%) and hypertension (36.5%).The lipid and uric acid metabolic defects in the psoriatics were no different from those found in controls.40% psoriasi patients had high plasmare in attività and urinari aldosterone levels.It suggest that psoriatic mcroangiopathy may be' responsabile for activating the renin -angitensin-aldosterone system and that this, in turn, may determinerà the hypertension.Since a high plasma renin attività is present in manu normotensive psoriasi patients, the microangipathy could be' due to' local or generalized arteriolar constriction induce by the hyperangiotensinaemia.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11388/146145
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