A severe exudative-crustous and proliferous dermatitis in a 2 year old sheep caused by Dermatophilus congolensis (observed for the first time in Italy), is reported. The disease was reproduced experimentally in sheep, goats, rabbits and guinea pigs, whose skin was treated in different ways before infection. E.L.I.S.A. and Immunoblotting tests carried out in experimentally infected sheep, showed the antigenic complexity of the pathogen and the existence of cross-immunity to the protein components. Intradermoreaction tests were carried out in all animals. The development of a positive reaction only in rabbits and guinea pigs, confirmed that these animals have a cellular immunity against Dermatophilus congolensis.

Dermatophilosis in sheep: first report in Italy, experimental reproduction and evaluation of immune response / Leoni, Antonio; Fadda, Manlio; Nieddu A., M; Pittau, Marco; Sanna, E; Pirino, Salvatore; Contini, A.. - In: BOLLETTINO DELLA SOCIETA' ITALIANA DI BIOLOGIA SPERIMENTALE. - ISSN 0037-8771. - 69:12(1993), pp. 775-782.

Dermatophilosis in sheep: first report in Italy, experimental reproduction and evaluation of immune response

LEONI, Antonio;FADDA, Manlio;PITTAU, Marco;PIRINO, Salvatore;
1993

Abstract

A severe exudative-crustous and proliferous dermatitis in a 2 year old sheep caused by Dermatophilus congolensis (observed for the first time in Italy), is reported. The disease was reproduced experimentally in sheep, goats, rabbits and guinea pigs, whose skin was treated in different ways before infection. E.L.I.S.A. and Immunoblotting tests carried out in experimentally infected sheep, showed the antigenic complexity of the pathogen and the existence of cross-immunity to the protein components. Intradermoreaction tests were carried out in all animals. The development of a positive reaction only in rabbits and guinea pigs, confirmed that these animals have a cellular immunity against Dermatophilus congolensis.
Dermatophilosis in sheep: first report in Italy, experimental reproduction and evaluation of immune response / Leoni, Antonio; Fadda, Manlio; Nieddu A., M; Pittau, Marco; Sanna, E; Pirino, Salvatore; Contini, A.. - In: BOLLETTINO DELLA SOCIETA' ITALIANA DI BIOLOGIA SPERIMENTALE. - ISSN 0037-8771. - 69:12(1993), pp. 775-782.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11388/140190
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